Results 71 to 80 of about 217 (107)
G024 Implication des canaux KATP dans le syndrome de repolarisation précoce
, 2009 La repolarisation précoce est une caractéristique électro cardiographique commune (1-5 % de la population générale). Une étude récente a montré que l’incidence de la repolarisation précoce (RP) est plus élevée chez les sujets ayant présenté une ...
Chatel, S. +25 more
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Corrigendum: A novel mutation in the KCNJ8 gene encoding the Kir6.1 subunit of an ATP‐sensitive potassium channel in a Japanese patient with Cantú syndrome [PDF]
Journal of the European Academy of Dermatology and Venereology, 2021 M. Chihara, A. Asahina, M. Itoh
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The Journal of biological chemistry, 2009 beta-Cell-type K(ATP) channels are octamers assembled from Kir6.2/KCNJ11 and SUR1/ABCC8. Adenine nucleotides play a major role in their regulation. Nucleotide binding to Kir6.2 inhibits channel activity, whereas ATP binding/hydrolysis on sulfonylurea receptor 1 (SUR1) opposes inhibition.
Marcus, Winkler +4 more
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Analysis of Two KCNJ11 Neonatal Diabetes Mutations, V59G and V59A, and the Analogous KCNJ8 I60G Substitution [PDF]
Journal of Biological Chemistry, 2009 Marcus Winkler +4 more
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, 2021 ÖZETGiriş: Erken repolarizasyon (ER), EKG'de J noktasının izoelektrik hatta göre ardışık 2derivasyonda en az 1 mm (0.1mV) yükselmesi olarak tanımlanmaktadır. Çoğunlukla yapısalkalp hastalığı bulunmayan kişilerde görülen Erken Repolarizasyon Sendromu (ERS),günümüzde Brugada Sendromu (BS) ile olan benzerlikleri nedeniyle `J Dalga Sendromları&apos ...
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The genes TRPV1, ABCC8, ABCC9, KCNJ8, KCNJ11, KCNMA1, KCNMB1-4 encode for macromolecular complexes that perform various functions in cells as subunits of ion channels and they are well known drug targets in pathological conditions.
ANTONACCI, MARINA
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, 2006 This research described in thesis was undertaken in an attempt to increase our knowledge of mechanisms by which lung cancer cells acquire the capacity to invade This is a critical step in cancer metastasis.
Pierce, Aisling
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Modeling of Cantú Syndrome in Zebrafish
, 2018 Although rare, Cantú syndrome (CS) is a debilitating syndrome without any specific therapy, caused by gain-of-function (GOF) mutations in KCNJ8 and ABCC9 genes that encode ATP-sensitive potassium (KATP) channels.
Singareddy, Soma Sekhara
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The ATP-sensitive potassium (KATP) channel directly regulates the microglia-mediated inflammatory response following CNS injury. To determine the putative role of the KATP channel in amyotrophic lateral sclerosis (ALS) pathology, we investigated whether ...
Vidal Taboada, José Manuel +5 more
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