Results 91 to 100 of about 7,235 (159)

Refractory testicular germ cell tumors are highly sensitive to the targeting of polycomb pathway demethylases KDM6A and KDM6B

Cell Communication and Signaling
Testicular germ cell tumors (TGCTs) can be treated with cisplatin-based therapy. However, a clinically significant number of cisplatin-resistant patients die from progressive disease as no effective alternatives exist.
Doha Shokry, Mehwish W. Khan, Christine Powell, Samantha Johnson, Brayden C. Rennels, Raya I. Boyd, Zhengyang Sun, Zeeshan Fazal, Sarah J. Freemantle, Maryanna H. Parker, Miranda D. Vieson, Jonathan P. Samuelson, Michael J. Spinella, Ratnakar Singh   +13 more
doaj   +1 more source

Síndrome de Kabuki: presentación de un Caso y Revisión de la Literatura

Salud Uninorte, 2016
El síndrome de Kabuki ( SK ) es una patología muy rara, descrita por primera vez en 1981 por Niikawa y Kuroki en Japón. Se han publicado cerca de 400 casos a nivel mundial.
Carlos Osorio Alarcón, Diego Olaya Mantilla, Carlos Silvera Redondo, Pilar Garavito Galofre   +3 more
doaj  

Shared diagnostic biomarkers in metabolic syndrome and coronary artery disease identified by integrated bioinformatics and machine learning. [PDF]

Endocr Connect
Wang N, Hu K, Zhang S, Zhao H, Pan T, Wang T, Zhang Y, Liu X.   +7 more
europepmc   +1 more source

Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway. [PDF]

Int J Mol Med
Rong Y, Yu H, Yin H, Li S, Wang J, Shen Z, Ding X, Bu F, Dai T, Wu G, Hua Z.   +10 more
europepmc   +1 more source

Intermittent myopic visual exposure triggers myopia progression via H3K27me3. [PDF]

Genome Med
Lei Y, Lin X, Ling X, Tan Y, Yuan J, Li Y, Di M, Pan Y, Zhong L, Feng Z, Jiao F, Hu C, Deng H, Pan M, Su J, Qu J, Chen W, Zhao F, Zhou X.   +18 more
europepmc   +1 more source

Endurance training increases tmTNF-α and IL-6 levels in several vital organs in rats: relationship with hypoxia markers. [PDF]

Front Mol Biosci
Galganski L, Zoladz JA, Jarmuszkiewicz W.   +2 more
europepmc   +1 more source

PML::RARA-negative APL-mimicking AML with a novel KMT2C::CREB3L2 fusion and RARA/RXRA-mediated sensitivity to all-trans retinoic acid. [PDF]

Ann Hematol
Ma L, Wu M.
europepmc   +1 more source

Fibulin 2 Deficiency Drives Epigenetic Hypertension. [PDF]

Hypertension
Han X, Sun Z.
europepmc   +1 more source

Sex Differences and Oxidative Stress in Cardiovascular Disease. [PDF]

Physiology (Bethesda)
Okoye DO, Aboagye E, Swenson S, Ngugi S, Shay K, Ogola BO.   +5 more
europepmc   +1 more source

Highlight on Dr. Rhonda Voskuhl: a pioneer in the exploration of sex differences in the immune response. [PDF]

Biol Sex Differ
Dunn SE.
europepmc   +1 more source