Results 81 to 90 of about 7,235 (159)
PLoS GeneticsGrowth deficiency is a characteristic feature of both Kabuki syndrome 1 (KS1) and Kabuki syndrome 2 (KS2), Mendelian disorders of the epigenetic machinery with similar phenotypes but distinct genetic etiologies.
Christine W Gao +8 more
doaj +1 more source
System Review about Function Role of ESCC Driver Gene KDM6A by Network Biology Approach
The Scientific World Journal, 2016 Background. KDM6A (Lysine (K)-Specific Demethylase 6A) is the driver gene related to esophageal squamous cell carcinoma (ESCC). In order to provide more biological insights into KDM6A, in this paper, we treat PPI (protein-protein interaction) network ...
Jihua Ran, Hui Li, Huiwu Li
doaj +1 more source
Epigenetic regulation of CD38/CD48 by KDM6A mediates NK cell response in multiple myeloma
Nature CommunicationsAnti-CD38 monoclonal antibodies like Daratumumab (Dara) are effective in multiple myeloma (MM); however, drug resistance ultimately occurs and the mechanisms behind this are poorly understood.
Jiye Liu +21 more
doaj +1 more source
KDM6A/B Demethylases in Gut Homeostasis
Cellular and Molecular Gastroenterology and Hepatology, 2023 openaire +3 more sources