Results 291 to 300 of about 56,140 (348)

Bidirectional regulation of KEAP1 BTB domain-based sensor activity. [PDF]

Redox Biol
Suzuki T, Takagi K, Iso T, Wen H, Zhang A, Hatakeyama T, Oshima H, Mizushima T, Yamamoto M.   +8 more
europepmc   +1 more source

Novel Duck Orthoreovirus Induces Ferroptosis in HD11 Cells by Hijacking Cellular Iron Metabolism and Promoting Iron Accumulation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Novel duck orthoreovirus (NDRV) infection induces severe splenic necrosis in ducks, resulting in a cascade of detrimental consequences, including immunosuppression, secondary infections, and diminished vaccine efficacy. Avian orthoreovirus (ARV) exhibits high tropism for macrophages, with splenic macrophages being identified as the primary target cells
Hongzhi Wang, Di Lei, Chenchen Jiang, Boyi Xu, Yi Tang, Rendong Fang, Zongfu Wu   +6 more
wiley   +1 more source

A novel biomimetic nanozyme orchestrates ulcerative colitis resolution by targeting KEAP1-NRF2-ARE pathway: Redox balance restoration, colonic barrier repair, immune homeostasis regulation. [PDF]

Mater Today Bio
Gong P, Wang Y, Qiu JH, Li G, Chen KW, Li Z, Wang X, Wang L.   +7 more
europepmc   +1 more source

Sappanone A Promotes Motor Function Recovery in Spinal Cord Injury Mice by Inhibiting Microglial M1 Polarization via Activation of the Keap1/Nrf2 Pathway. [PDF]

FASEB J
Ren L, Chen Y, Xia J, Song X, Tao L, Li J, Xu L, Lü H, Hu J.   +8 more
europepmc   +1 more source

Lachnospiraceae bacterium alleviates alcohol-associated liver disease by enhancing N-acetyl-glutamic acid levels and inhibiting ferroptosis through the KEAP1-NRF2 pathway

Hejiao Zhang, Qiang Hu, Yong Zhang, Lei Yang, Shanshan Tian, Xinru Zhang, Haiyuan Shen, Hang Shu, Linxi Xie, Dongqing Wu, Liangliang Zhou, Xiaoli Wei, Chen Cheng, Jiali Jiang, Hua Wang, Cailiang Shen, Derun Kong, Long Xu   +17 more
openalex   +1 more source

Chronic Psychological Stress Activates TRP/TAM/CXCL1 Signaling to Promote Breast Cancer Adipocyte Lipolysis via KEAP1 m⁶A Demethylation. [PDF]

Research (Wash D C)
Zhan D, She Y, Zhang X, Zhang J, Wang S, Hong S, Zheng Y, Wang N, Wang Z.   +8 more
europepmc   +1 more source

Petunidin alleviates diabetic nephropathy injury via the inhibition of oxidative stress and ferroptosis through the Keap1/mitoNQO1 pathway. [PDF]

Front Cell Dev Biol
Qiu Y, Chen C, Li X, Chang Y, Zou X, Yan X, Mao W, Wu G, Li S, Chen Y.   +9 more
europepmc   +1 more source

The electrophilic metabolite of kynurenine, kynurenine-CKA, targets C151 in Keap1 to derepress Nrf2

Feng J, Carreño M, Jung H, Naidu SD, Arroyo-Diaz N, Ang AD, Kulkarni B, Kisielewski D, Suzuki T, Yamamoto M, Hayes JD, Honda T, Leon-Ruiz B, Eggler AL, Vitturi DA, Dinkova-Kostova AT.   +15 more
europepmc   +1 more source

Correction: Astragaloside IV alleviates tacrolimus-induced chronic nephrotoxicity via p62-Keap1-Nrf2 pathway. [PDF]

Front Pharmacol
Gao P, Du X, Liu L, Xu H, Liu M, Guan X, Zhang C.   +6 more
europepmc   +1 more source

RNA Adenosine Deaminases Modulate Oxidative Stress-Mediated Hepatocellular Carcinoma Cell Damage via KEAP1/Nrf2 Axis

Changquan Li, Haitao Wang
openalex   +1 more source