Results 301 to 310 of about 56,140 (348)

Dietary Phytochemicals Targeting NRF2 Against Skin Cellular Senescence: Mechanistic Insights and Potential for Functional Food Development. [PDF]

Biology (Basel)
Liu Y, Wang R, Liu H, Tu Z.
europepmc   +1 more source

Mechanisms of Bisphenol A exposure on oral squamous cell carcinoma: a multidimensional network analysis. [PDF]

BMC Pharmacol Toxicol
Huang J, Han S, Guo M, Zhang T, Zheng Y, Ma N.   +5 more
europepmc   +1 more source

Protein arginine methyltransferase 7-mediated arginine mono-methylation stabilizes SRY-box transcription factor 9 to promote non-small cell lung cancer progression. [PDF]

Mol Biomed
Zhang L, Xiang J, Feng Y, Shen G, Huang X, Fang T, Zhu Y, Ren H, Liu C.   +8 more
europepmc   +1 more source

Rationale and design for a phase IIIb trial of first-line tremelimumab plus durvalumab versus pembrolizumab, in combination with chemotherapy, in patients with non-squamous metastatic non-small-cell lung cancer and mutations or co-mutations in <i>STK11, KEAP1</i>, or <i>KRAS</i>: the TRITON study. [PDF]

Ther Adv Med Oncol
Skoulidis F, Borghaei H, Garon EB, Leal TA, Kaufman J, Liu SV, Nadler E, Patel SP, Peters S, Ricciuti B, Gautam A, Emeribe U, Luciani-Silverman L, Heymach JV.   +13 more
europepmc   +1 more source

Stress-NRF2 response axis polarizes tumor macrophages and undermines immunotherapy. [PDF]

J Immunother Cancer
Schaer DJ, Schulthess-Lutz N, Baselgia L, Kunasingam K, Humar R, Hansen K, Eschment M, Duerst E, Vallelian F.   +8 more
europepmc   +1 more source

Targeting NRF2 With Isoeugenol: A Promising Small Molecule for Neurodegenerative, Metabolic, and Chronic Inflammatory Disorders. [PDF]

Oxid Med Cell Longev
Silva A, Silva S, Rodrigues B, Simões G, Dinis I, Freitas M, Resende R, Bicker J, Fortuna A, Silva MM, Santos AE, Pinho SA, Neves B, Pereira CF, Cruz MT.   +14 more
europepmc   +1 more source

Corrigendum to “Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3β in the impairment of the NRF2 response” [Redox Biol. 76 (2024) 103339]

Arabela Sanz‐Alcázar, Marta Portillo-Carrasquer, Fabien Delaspre, Maria Pazos-Gil, Jordi Tamarit, Joaquim Ros, Elisa Cabiscol   +6 more
openalex   +1 more source

Lifetime Deletion of Skeletal Muscle Keap1 Attenuates Aging-Induced Cardiac Dysfunction via an Nrf2-Antioxidant Mechanism. [PDF]

Antioxidants (Basel)
Sharma K, Pribil Pardun S, Dhyani N, Zucker IH, Nair BG, Nair SS, Kumar V, Gao L.   +7 more
europepmc   +1 more source

KEAP1 C151 active site catalysis drives electrophilic signaling to upregulate cytoprotective enzyme expression. [PDF]

Redox Biol
Schnell MR, Zhai T, Ragwan ER, Jung H, Zhang J, Lagalante AF, Kung Y, Kraut DA, Huang Z, Eggler AL.   +9 more
europepmc   +1 more source

Structural characterization of KEAP1 variants to guide the design of KEAP1-Nrf2 peptide inhibitors

, 2020
openaire   +1 more source