Results 101 to 110 of about 10,759 (233)
Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor. [PDF]
Lymphocyte attachment to high endothelial venules within lymph nodes is mediated by the peripheral lymph node homing receptor (pnHR), originally defined on mouse lymphocytes by the MEL-14 mAb.
Fennie, C+4 more
core
Prenatal diagnosis of morquio disease type A using a simple fluorometric enzyme assay [PDF]
A new fluorogenic substrate, 4 methylumbelliferyl B-D-6-sulphogalactoside, was used for the assay of galactose-6-sulphate sulphatase activity in chorionic villi, cultured villus cells, and amniocytes. The fluorometric assay is much more convenient than
Diggelen, O.P. (Otto) van+6 more
core +2 more sources
ABSTRACT This paper reviews biomarkers in lysosomal disease according to their categories and definitions. There are numerous biomarkers in lysosomal diseases. Some are disease or organ‐specific, but most are not. Organ‐specific biomarkers are especially useful, but most biomarkers help with diagnosis, assessing disease severity, prognosis, and ...
Raphael Schiffmann
wiley +1 more source
A case study: Glycosaminoglycan profiles of autologous chondrocyte implantation (ACI) tissue improves as the tissue matures [PDF]
Background Autologous chondrocyte implantation (ACI) has been used to treat cartilage defects in thousands of patients worldwide with good clinical effectiveness 10–20 years after implantation.
Kuiper, NJ+3 more
core +1 more source
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
Interactions between sulfated glycosaminoglycans (GAGs) and the adhesin OmcB of Chlamydia species are explored using a surface‐based binding assay and cell assays. Increased sulfation and molecular weight enhance GAG binding and reduce bacterial attachment, with heparin exhibiting superior inhibitory effects.
Sebastian Wintgens+7 more
wiley +1 more source
Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions [PDF]
Ministero dell’Istruzione, dell’Università e della Ricerca (MIUR) is acknowl-edged for funding to EB (FFABR 2017,“Fondo per ilfinanziamento delle attività base di ricerca”).AFM thanks the support of the Spanish Ministerio de Economía y Competitividad (GrantMAT2015-65184-C2-2-R)
Emiliano Bedini+3 more
openaire +4 more sources
Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels. [PDF]
Previous work has revealed robust dorsal root ganglia neurite growth in hydrogels of chondroitin sulfate. In the current work, it was determined whether addition of a synthetic bioactive peptide could augment neurite growth in these matrices via enhanced
Beier, Brooke L+3 more
core +1 more source
Abstract Prostate cancer (PrCa) is highly prevalent in the Western world. Currently, however, there are many unmet needs in PrCa care, for example in distinguishing between clinically significant and indolent cases in early phases of the disease. ANO7 is a prostate‐specific gene associated with PrCa risk and prognosis, but its exact function in the ...
Olli Metsälä+5 more
wiley +1 more source
Evidence for the role of proteoglycans in cation-mediated gene transfer [PDF]
We report evidence that gene complexes, consisting of polycations and plasmid DNA enter cells via binding to membrane-associated proteoglycans. Treatment of HeLa cells with sodium chlorate, a potent inhibitor of proteoglycan sulfation, reduced luciferase
Baldeschwieler, John D.+1 more
core +1 more source