Instant determination of the potential biomarker heparan sulfate in human plasma by a mix-and-read fluorescence assay [PDF]
arXiv, 2017 Heparan sulfate (HS) is a linear, polydisperse sulfated polysaccharide belonging to the glycosaminoglycan family. HS proteoglycans are ubiquitously found at the cell surface and extracellular matrix in animal species. HS is involved in the interaction with a wide variety of proteins and the regulation of many biological activities.
arxiv
Integration of clinical data with a genome‐scale metabolic model of the human adipocyte
Molecular Systems Biology, 2013 We evaluated the presence/absence of proteins encoded by 14 077 genes in adipocytes obtained from different tissue samples using immunohistochemistry. By combining this with previously published adipocyte‐specific proteome data, we identified proteins ...
Adil Mardinoglu +10 more
doaj +1 more source
Diagnostic Pathology, 2011 Mucopolysaccharidosis type IVA or Morquio A syndrome is characterized by the lack of N-acetylgalactosamine-6-sulfate-sulfatase and the accumulation of keratan sulfate and chondroitin-6-sulfate in the lysosomes.
Chkioua Latifa +4 more
doaj +1 more source
Glycosaminoglycans and Proteoglycans
Pharmaceuticals, 2018 In this editorial to MDPI Pharmaceuticals special issue “Glycosaminoglycans and Proteoglycans” we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan,
Vitor H. Pomin, Barbara Mulloy
doaj +1 more source
Damage due to salt crystallization in porous media [PDF]
arXiv, 2009 We investigate salt crystallization in porous media that can lead to their disintegration. For sodium sulfate we show for the first time experimentally that when anhydrous crystals are wetted with water, there is very rapid growth of the hydrated form of sulfate in clusters that nucleate on anhydrous salt micro crystals.
arxiv
Iron oxide-coupled CRISPR-nCas9-based genome editing assessment in mucopolysaccharidosis IVA mice
Molecular Therapy: Methods & Clinical Development, 2023 Mucopolysaccharidosis (MPS) IVA is a lysosomal storage disorder caused by mutations in the GALNS gene that leads to the lysosomal accumulation of keratan sulfate (KS) and chondroitin 6-sulfate, causing skeletal dysplasia and cardiopulmonary complications.
Andrés Felipe Leal +5 more
doaj
Structural Characterization and Anticoagulant Activities of a Keratan Sulfate-like Polysaccharide from the Sea Cucumber Holothuria fuscopunctata. [PDF]
Mar Drugs, 2023 Chen R +7 more
europepmc +1 more source
Large-time behavior of a two-scale semilinear reaction-diffusion system for concrete sulfatation [PDF]
arXiv, 2013 We study the large-time behavior of (weak) solutions to a two-scale reaction-diffusion system coupled with a nonlinear ordinary differential equations modeling the partly dissipative corrosion of concrete (/cement)-based materials with sulfates. We prove that as $t\to\infty$ the solution to the original two-scale system converges to the corresponding ...
arxiv
Increased Urinary Excretion of Keratan Sulfate in Fucosidosis [PDF]
, 1978 H. Greiling +3 more
openalex +1 more source
Bisphosphonate Treatment in a Patient Affected by MPS IVA with Osteoporotic Phenotype
Case Reports in Medicine, 2013 Morquio A syndrome (Mucopolysaccharidosis type IVA) (MPS IVA) is a rare inherited metabolic disorder characterized by the defective degradation of keratan sulfate and chondroitin-6-sulfate.
Albina Tummolo +7 more
doaj +1 more source