Results 101 to 110 of about 3,241,173 (293)

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity

open access: yesAdvanced Science
Keratins are an integral part of cell structure and function. Here, it is shown that ectopic expression of a truncated isoform of keratin 81 (tKRT81) in breast cancer is upregulated in metastatic lesions compared to primary tumors and patient‐derived ...
Diane S. Kang   +14 more
doaj   +1 more source

The interaction between the HPV E1^E4 protein and the cell cytoskeleton.

open access: yes, 2007
Papillomaviruses are small DNA viruses, which cause benign and malignant lesions in the differentiated epithelium of mammals and birds. A small subset of human papillomaviruses (HPV's), have been identified as the etiological agent of cervical cancer ...
Laskey, P.
core  

The comparative analysis of the methods for keratin extraction from sheep wool and human hair

open access: yes, 2020
Nowadays, biopolymers such as keratins are widely used in biomedicine due to their low toxicity, biocompatibility, and biodegradability. At the molecular level, keratins differ from other structural proteins by a high content of disulfide bonds, which ...
V. Mykhaliuk, V. Havryliak
core   +1 more source

A curated catalog of canine and equine keratin genes. [PDF]

open access: yes, 2017
Keratins represent a large protein family with essential structural and functional roles in epithelial cells of skin, hair follicles, and other organs. During evolution the genes encoding keratins have undergone multiple rounds of duplication and humans ...
Kim D. Pruitt   +22 more
core   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

open access: yesAdvanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao   +6 more
wiley   +1 more source

Tandem LIM domain-containing proteins, LIMK1 and LMO1, directly bind to force-bearing keratin intermediate filaments

open access: yesCell Reports
Summary: The cytoskeleton of the cell is constantly exposed to physical forces that regulate cellular functions. Selected members of the LIM (Lin-11, Isl-1, and Mec-3) domain-containing protein family accumulate along force-bearing actin fibers, with ...
Dah Som Kim   +8 more
doaj   +1 more source

Unique gene expression profile of the proliferating Xenopus tadpole tail blastema cells deciphered by RNA-sequencing analysis.

open access: yesPLoS ONE, 2015
Organ regenerative ability depends on the animal species and the developmental stage. The molecular bases for variable organ regenerative ability, however, remain unknown.
Hiroshi Tsujioka   +4 more
doaj   +1 more source

Properties of Intermediate Filament Networks Assembled from Keratin 8 and 18 in the Presence of Mg2+

open access: yes, 2012
The mechanical properties of epithelial cells are modulated by structural changes in keratin intermediate filament networks. To investigate the relationship between network architecture and viscoelasticity, we assembled keratin filaments from recombinant
Marti, Othmar   +5 more
core   +1 more source

Interface Wettability Transition‐Driven Drug Release and Dual‐Phase Functionalization in Implant Abutment

open access: yesAdvanced Science, EarlyView.
A temporally controlled drug release coating is developed for abutments using a superhydrophobic coating self‐assembled on mesoporous silica. This surface provides sequential functionality: initial contamination resistance through non‐wetting, followed by controlled drug release via wettability transition.
Zhongchao Wang   +8 more
wiley   +1 more source

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