Results 11 to 20 of about 3,241,173 (293)

Glycoconjugates and keratin 18 define subsets of taste cells [PDF]

The Histochemical Journal, 1995
Sections of neonatal, normal adult and denervated adult rat tongue were examined with lectin histochemistry. Attention was focused upon intragemmal cells (cells within the taste bud) and the surrounding perigemmal cells. Informative staining patterns were observed with four of 12 lectins: Ulex europaeus (UEA-I), Bauhinia purpurea (BPA), Helix pomatia ...
Zeng, Qun, Lawton, Anne, Oakley, Bruce
openaire   +4 more sources

Keratin 18 is associated with a subset of older taste cells in the rat [PDF]

Differentiation, 1995
All or nearly all intragemmal (elongated) cells of rat taste buds were immunopositive for keratins 7, 8, and 19. In contrast, keratin 18 was detected in 19 +/- 5 cells per taste bud (mean +/- sd), or about 25% of the intragemmal cells. During taste bud development keratins 7, 8, and 19 were evident initially in polygonal cells and later in elongated ...
Zhang, Chunxiao, Cotter, Murray, Lawton, Anne, Oakley, Bruce, Wong, Lianna, Zeng, Qun   +5 more
openaire   +4 more sources

Keratin 18 is an integral part of the intermediate filament network in murine skeletal muscle.

Am J Physiol Cell Physiol, 2020
Intermediate filaments (IFs) contribute to force transmission, cellular integrity, and signaling in skeletal muscle. We previously identified keratin 19 (Krt19) as a muscle IF protein. We now report the presence of a second type I muscle keratin, Krt18.
Muriel JM, O'Neill A, Kerr JP, Kleinhans-Welte E, Lovering RM, Bloch RJ.   +5 more
europepmc   +4 more sources

Tescalcin over-expression increases Keratin 18 and 19 in K562 cells

Journal of Basic and Clinical Health Sciences, 2022
Tescalcin (TESC) has been shown to be essential in mammalian cells as a regulator of intracellular Ca2+. Ca2+ is a second messenger functioning in many metabolic pathways as well as in cell differentiation, cell size and the cell cycle. K562 cells over-expressing TESC change their morphology and adopt adherent properties.
Hande Efe, Özge Uysal Yoca, Umut Özerk Önkol, Zeynep Yuce   +3 more
openaire   +4 more sources

Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma in vitro and in vivo [PDF]

Frontiers in Cell and Developmental Biology, 2020
Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer-related death worldwide. Xanthohumol is a prenylated flavonoid isolated from hops.
Shuying Yin, Shuying Yin, Mengqiu Song, Mengqiu Song, Ran Zhao, Ran Zhao, Xuejiao Liu, Xuejiao Liu, Woo Kyu Kang, Jeong Min Lee, Young Eun Kim, Chengjuan Zhang, Jung-Hyun Shim, Kangdong Liu, Kangdong Liu, Kangdong Liu, Zigang Dong, Zigang Dong, Zigang Dong, Mee-Hyun Lee, Mee-Hyun Lee, Mee-Hyun Lee   +21 more
doaj   +2 more sources

Skeletal muscle adaptations following eccentric contractions are not mediated by keratin 18.

J Appl Physiol (1985)
The molecular processes that underlie the changes in skeletal muscle following eccentric exercise training are complex and involve multiple factors. Our findings indicate that Krt18 may not play a significant role in muscle adaptations following eccentric exercise training, likely due to its low expression in skeletal muscle.
Ganjayi MS, Frank SW, Krauss TA, York ML, Bloch RJ, Baumann CW.   +5 more
europepmc   +3 more sources

Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18. [PDF]

J Biol Chem, 2016
Keratins 8/18 (K8/18) are phosphoglycoproteins and form the major intermediate filament network of simple epithelia. The three O-GlcNAcylation (Ser , Ser , and Ser ) and two phosphorylation (Ser and Ser ) serine sites on K18 are well characterized.
Kakade PS, Budnar S, Kalraiya RD, Vaidya MM.   +3 more
europepmc   +6 more sources

The relationship between keratin 18 and epithelial-derived tumors: as a diagnostic marker, prognostic marker, and its role in tumorigenesis [PDF]

Frontiers in Oncology
As a structural protein, keratin is mainly expressed in epithelial cells and skin appendages to provide mechanical support and external resistance. The keratin family has a total of 54 members, which are divided into type I and type II.
Jiazhi Yan, Aiwei Yang, Shuo Tu
doaj   +2 more sources

Cell Death and Prognosis of Mortality in Alcoholic Hepatitis Patients Using Plasma Keratin-18. [PDF]

Gene Expr, 2017
Alcoholic liver disease encompasses the progressive stages of liver dysfunction that culminates in alcoholic cirrhosis (AC) and in severe cases alcoholic hepatitis (AH). Currently, prognostic scores have limited specificity and sensitivity. Plasma keratin-18 (K18) levels are elevated during liver disease and may be biomarkers of outcome.
Woolbright BL, Bridges BW, Dunn W, Olson JC, Weinman SA, Jaeschke H.   +5 more
europepmc   +4 more sources

Keratin 18 attenuates estrogen receptor α-mediated signaling by sequestering LRP16 in cytoplasm [PDF]

BMC Cell Biology, 2009
Background Oncogenesis in breast cancer is often associated with excess estrogen receptor α(ERα) activation and overexpression of its coactivators. LRP16 is both an ERα target gene and an ERα coactivator, and plays a crucial role in ERα activation and ...
Si Yiling, Chen Meixia, Zhao Yali, Yin Xiaoyun, Wu Zhiqiang, Meng Yuanguang, Yang Jie, Fu Xiaobing, Han Weidong   +8 more
doaj   +3 more sources