Results 21 to 30 of about 3,241,173 (293)

Keratin as a Potential Prognostic Biomarker for Breast Cancer Progression: An Evidence-Synthesizing Narrative Review [PDF]

open access: yesBreast Cancer: Targets and Therapy
Astrid Feinisa Khairani,1 Karina Fitria Alhaq,2 Regina Indrasari Herriyanto,2 Mh Busra Fauzi,3 Nayla Majeda Alfarafisa1 1Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Faculty of Medicine,
Khairani AF   +4 more
doaj   +2 more sources

Keratin-18 și MicroARN – biomarkerii leziunilor hepatice de origine medicamentoasă

open access: yesBuletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2019
Leziunile hepatice induse de medicamente (LHIM) sunt patologii care se dezvoltă independent de doza de medicament (pentru unele medicamente), calea sau durata administrării. Leziunile hepatice induse de medicamente fac parte din cauzele care stau la baza
Ana Veselovskaia, Anatolie Vişnevschi
doaj   +1 more source

O‑GlcNAcylation Facilitates the Interaction between Keratin 18 and Isocitrate Dehydrogenases and Potentially Influencing Cholangiocarcinoma Progression [PDF]

open access: yesACS Central Science
Xiangfeng Meng   +12 more
doaj   +2 more sources

Correction to “O‑GlcNAcylation Facilitates the Interaction between Keratin 18 and Isocitrate Dehydrogenases and Potentially Influencing Cholangiocarcinoma Progression” [PDF]

open access: yesACS Central Science
Xiangfeng Meng   +12 more
doaj   +2 more sources

Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders

open access: yesHuman Genomics, 2022
Intermediate filament (IntFil) genes arose during early metazoan evolution, to provide mechanical support for plasma membranes contacting/interacting with other cells and the extracellular matrix. Keratin genes comprise the largest subset of IntFil genes.
Minh Ho   +6 more
doaj   +1 more source

The Evolution of Circulating Biomarkers for Use in Acetaminophen/Paracetamol-Induced Liver Injury in Humans: A Scoping Review

open access: yesLivers, 2023
Acetaminophen (APAP) is a widely used drug, but overdose can cause severe acute liver injury. The first reports of APAP hepatotoxicity in humans were published in 1966, shortly after the development of alanine aminotransferase (ALT) and aspartate ...
Mitchell R. McGill, Steven C. Curry
doaj   +1 more source

Keratin 18, Apoptosis, and Liver Disease in Children [PDF]

open access: yesCurrent Pediatric Reviews, 2011
Keratins, a major component of epithelial cell intermediate filaments, provide structural support to the cell and are important for the maintenance of structural integrity. Beyond its role of structural integrity in hepatocytes, keratin 18 (K18) is a known marker of apoptosis and has been proposed as an indicator of progression in chronic liver ...
Yanci O, Mannery   +2 more
openaire   +2 more sources

Spatiotemporal expression of zebrafish keratin 18 during early embryogenesis and the establishment of a keratin 18:RFP transgenic line [PDF]

open access: yesGene Expression Patterns, 2006
Zebrafish cytokeratin 18 (K18) is one of the type I keratin genes expressed the earliest after amputation of the zebrafish fin, but its spatiotemporal expression during early development is unclear. Whole-mount in situ hybridization revealed that k18 was a maternally inherited gene and that its expression is restricted to the single layer of enveloping
Yun-Hsin, Wang   +3 more
openaire   +2 more sources

Tumor suppression by RNA from C/EBPβ 3'UTR through the inhibition of protein kinase Cε activity. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Since the end of last century, RNAs from the 3'untranslated region (3'UTR) of several eukaryotic mRNAs have been found to exert tumor suppression activity when introduced into malignant cells independent of their whole mRNAs.
Ying Wang, Da-Quan Sun, Ding-Gan Liu
doaj   +1 more source

Characterization of Long-Term Cultured Murine Submandibular Gland Epithelial Cells. [PDF]

open access: yesPLoS ONE, 2016
Human and rat salivary gland cell lines derived from tumors or genetic modification are currently available for research. Here, we attempted to culture and characterize long-term cultured cells spontaneously derived from wild type murine submandibular ...
Kazuhiro Ikeura   +4 more
doaj   +1 more source

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