Keratin as a Potential Prognostic Biomarker for Breast Cancer Progression: An Evidence-Synthesizing Narrative Review [PDF]
Astrid Feinisa Khairani,1 Karina Fitria Alhaq,2 Regina Indrasari Herriyanto,2 Mh Busra Fauzi,3 Nayla Majeda Alfarafisa1 1Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Faculty of Medicine,
Khairani AF +4 more
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Keratin-18 și MicroARN – biomarkerii leziunilor hepatice de origine medicamentoasă
Leziunile hepatice induse de medicamente (LHIM) sunt patologii care se dezvoltă independent de doza de medicament (pentru unele medicamente), calea sau durata administrării. Leziunile hepatice induse de medicamente fac parte din cauzele care stau la baza
Ana Veselovskaia, Anatolie Vişnevschi
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O‑GlcNAcylation Facilitates the Interaction between Keratin 18 and Isocitrate Dehydrogenases and Potentially Influencing Cholangiocarcinoma Progression [PDF]
Xiangfeng Meng +12 more
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Correction to “O‑GlcNAcylation Facilitates the Interaction between Keratin 18 and Isocitrate Dehydrogenases and Potentially Influencing Cholangiocarcinoma Progression” [PDF]
Xiangfeng Meng +12 more
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Intermediate filament (IntFil) genes arose during early metazoan evolution, to provide mechanical support for plasma membranes contacting/interacting with other cells and the extracellular matrix. Keratin genes comprise the largest subset of IntFil genes.
Minh Ho +6 more
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Acetaminophen (APAP) is a widely used drug, but overdose can cause severe acute liver injury. The first reports of APAP hepatotoxicity in humans were published in 1966, shortly after the development of alanine aminotransferase (ALT) and aspartate ...
Mitchell R. McGill, Steven C. Curry
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Keratin 18, Apoptosis, and Liver Disease in Children [PDF]
Keratins, a major component of epithelial cell intermediate filaments, provide structural support to the cell and are important for the maintenance of structural integrity. Beyond its role of structural integrity in hepatocytes, keratin 18 (K18) is a known marker of apoptosis and has been proposed as an indicator of progression in chronic liver ...
Yanci O, Mannery +2 more
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Spatiotemporal expression of zebrafish keratin 18 during early embryogenesis and the establishment of a keratin 18:RFP transgenic line [PDF]
Zebrafish cytokeratin 18 (K18) is one of the type I keratin genes expressed the earliest after amputation of the zebrafish fin, but its spatiotemporal expression during early development is unclear. Whole-mount in situ hybridization revealed that k18 was a maternally inherited gene and that its expression is restricted to the single layer of enveloping
Yun-Hsin, Wang +3 more
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Tumor suppression by RNA from C/EBPβ 3'UTR through the inhibition of protein kinase Cε activity. [PDF]
BACKGROUND: Since the end of last century, RNAs from the 3'untranslated region (3'UTR) of several eukaryotic mRNAs have been found to exert tumor suppression activity when introduced into malignant cells independent of their whole mRNAs.
Ying Wang, Da-Quan Sun, Ding-Gan Liu
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Characterization of Long-Term Cultured Murine Submandibular Gland Epithelial Cells. [PDF]
Human and rat salivary gland cell lines derived from tumors or genetic modification are currently available for research. Here, we attempted to culture and characterize long-term cultured cells spontaneously derived from wild type murine submandibular ...
Kazuhiro Ikeura +4 more
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