Results 121 to 130 of about 191,552 (354)

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source

Evaluation of Platelet-Derived Extracellular Vesicles in Gingival Fibroblasts and Keratinocytes for Periodontal Applications [PDF]

, 2022
Miquel Antich-Rosselló, Marta Munar‐Bestard, María Antonia Forteza‐Genestra, Javier Calvo, Antoni Gayà, Marta Monjo, Joana Maria Ramis   +6 more
openalex   +1 more source

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng, Heyan Huang, Xiangru Chen, Jie Fu, Zhiwei Sun, Mengjuan Tao, Jianwei Mao, Fei Zhang, Zhou Wan, Yuan Li, Dingan Wu, Chuchao Zhou, Yanqing Yang   +12 more
wiley   +1 more source

Critical role of keratinocytes in cutaneous immune responses

Exploration of Immunology
Keratinocytes play an integral role in the human epidermis, serving as a barrier between the internal and external environment. They are immune-competent cells involved in both innate and adaptive cutaneous immune responses, crucial for maintaining skin ...
Rakesh Kumar Gupta, Poonam Wasnik, Deepankar Mondal, Dhananjay Shukla   +3 more
doaj   +1 more source

Human adipose-derived stem cells cultured in keratinocyte serum free medium: Donor’s age does not affect the proliferation and differentiation capacities [PDF]

, 2013
Dah‐Ching Ding, Hsiang-Lan Chou, Wei‐Ting Hung, Hwan-Wun Liu, Tang‐Yuan Chu   +4 more
openalex   +1 more source

CARD14 is a Novel Regulator of MYC Expression and Function in Human Keratinocytes [PDF]

, 2023
Stanley B. DeVore, Matthew Schuetz, Henry Lujan, David Ohayon, Arjun Kothari, Hua He, Jennifer Hahn, Latha Satish, Andrew B. Herr, Jocelyn M. Biagini Myers, Lisa J. Martin, Dorothy M. Supp, Gurjit K. Khurana Hershey   +12 more
openalex   +1 more source

Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome. [PDF]

, 2020
Netherton syndrome (NS) is a monogenic skin disease resulting from loss of function of lymphoepithelial Kazal-type-related protease inhibitor (LEKTI-1).
Butcher, Anna M, Cau, Laura, Dupont, Christopher L, Gallo, Richard L, Horswill, Alexander R, Hovnanian, Alain, Kaul, Drishti, Khalil, Shadi, Sanford, James A, Wang, Yichen, Williams, Michael R, Zaramela, Livia S, Zengler, Karsten   +12 more
core  

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

A survey of multiple candidate probiotic bacteria reveals specificity in the ability to modify the effects of key wound pathogens

Microbiology Spectrum
We have evaluated the inhibitory effects of supernatants and lysates derived from several candidate probiotics, on the growth and biofilm formation of wound pathogens, and their ability to protect human primary epidermal keratinocytes from the toxic ...
Muna Alhubail, Andrew J. McBain, Catherine A. O'Neill   +2 more
doaj   +1 more source

Adhesion Molecules. I: Keratinocyte-Keratinocyte Interactions; Cadherins and Pemphigus

Journal of Investigative Dermatology, 1995
During the last few years, considerable progress has been made in our understanding of the structure and function of cadherins and of the pathophysiology of pemphigus. Cadherins are a multiple gene family of Ca(++)-dependent cell adhesion molecules with a typical single-spanning transmembrane structure.
openaire   +2 more sources