Results 31 to 40 of about 108,825 (100)

Basal Cell Carcinoma in Patients over 80 Years Presenting for Surgical Excision: Clinical Characteristics and Surgical Outcomes

open access: yesCurrent Oncology
Background. Complete basal cell carcinoma (BCC) excision remains the most common treatment modality. However, its clinical characteristics and the surgical outcomes achieved in patients over 80 years—often with several medical comorbidities and ...
Konstantinos Seretis   +5 more
doaj   +1 more source

MicroRNA-221-3p Targets THBS1 to Promote Wound Healing in Diabetes

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2023
Keyan Hu,1,2,* Xueying Liu,1,* Hongfeng Chang,1 Yi Zhang,1 Hui Zhou,3 Lei Liu,1 Xin Zhang,1 Ziying Jiao,4 Bing Shen,4 Qiu Zhang1 1Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’
Hu K   +9 more
doaj  

Design of an Integrated Microvascularized Human Skin-on-a-Chip Tissue Equivalent Model

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Tissue-engineered skin constructs have been under development since the 1980s as a replacement for human skin tissues and animal models for therapeutics and cosmetic testing.
Christian F. E. Jones   +6 more
doaj   +1 more source

miR-21 Promotes Keratinocyte Migration and Re-epithelialization During Wound Healing

open access: yesInternational Journal of Biological Sciences, 2011
MicroRNAs involved in keratinocyte migration and wound healing are largely unknown. Here, we revealed the indispensable role of miR-21 in keratinocyte migration and in re-epithelialization during wound healing in mice.
Xue Yang, Jun Wang, Shui-Long Guo, Kai-Ji Fan, Jun Li, You-Liang Wang, Yan Teng, Xiao Yang
doaj  

Single-Cell Transcriptomics Reveals Spatial and Temporal Turnover of Keratinocyte Differentiation Regulators

open access: yesFrontiers in Genetics, 2019
Keratinocyte differentiation requires intricately coordinated spatiotemporal expression changes that specify epidermis structure and function. This article utilizes single-cell RNA-seq data from 22,338 human foreskin keratinocytes to reconstruct the ...
Alex Finnegan   +9 more
doaj   +1 more source

Keratinocytes can modulate and directly initiate nociceptive responses

open access: yeseLife, 2015
How thermal, mechanical and chemical stimuli applied to the skin are transduced into signals transmitted by peripheral neurons to the CNS is an area of intense study.
Kyle M Baumbauer   +9 more
doaj   +1 more source

Geniposidic Acid from Eucommia ulmoides Oliver Staminate Flower Tea Mitigates Cellular Oxidative Stress via Activating AKT/NRF2 Signaling

open access: yesMolecules, 2022
Eucommia ulmoides Oliver staminate flower (ESF) tea enjoys a good reputation in folk medicine and displays multiple bioactivities, such as antioxidant and antifatigue properties. However, the underlying biological mechanisms remain largely unknown.
Shuo Cheng   +6 more
doaj   +1 more source

Fabrication of Human Keratinocyte Cell Clusters for Skin Graft Applications by Templating Water-in-Water Pickering Emulsions

open access: yesBiomimetics, 2019
Most current methods for the preparation of tissue spheroids require complex materials, involve tedious physical steps and are generally not scalable. We report a novel alternative, which is both inexpensive and up-scalable, to produce large quantities ...
Sevde B. G. Celik   +5 more
doaj   +1 more source

Honey and Chamomile Activate Keratinocyte Antioxidative Responses via the KEAP1/NRF2 System

open access: yesClinical, Cosmetic and Investigational Dermatology, 2020
Tatsuya Ogawa, 1 Yosuke Ishitsuka, 1 Yoshiyuki Nakamura, 1 Naoko Okiyama, 1 Rei Watanabe, 1, 2 Yasuhiro Fujisawa, 1 Manabu Fujimoto 1, 2 1Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan; 2Department of ...
Ogawa T   +6 more
doaj  

Immune Control by TRAF6-Mediated Pathways of Epithelial Cells in the EIME (Epithelial Immune Microenvironment)

open access: yesFrontiers in Immunology, 2019
In the protective responses of epithelial tissues, not only immune cells but also non-immune cells directly respond to external agents. Epithelial cells can be involved in the organization of immune responses through two phases.
Teruki Dainichi   +5 more
doaj   +1 more source

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