Results 11 to 20 of about 137,265 (305)
Long non-coding RNAs in cutaneous biology and keratinocyte carcinomas [PDF]
, 2022 Long non-coding RNAs (lncRNAs) are a largely uncharacterized group of non-coding RNAs with diverse regulatory roles in various biological processes. Recent observations have elucidated the functional roles of lncRNAs in cutaneous biology, e.g.
Nissinen Liisa +2 more
core +1 more source
Living with Keratinocytes [PDF]
Stem Cell Reports, 2018 A feature distinguishing human hematopoietic and epithelial stem cells from other equally fascinating stem cells is perhaps their easier translation into a clinical setting. We have devoted nearly our entire scientific career in trying to turn our understanding of epithelial stem cell biology into something that could help people suffering from ...
Pellegrini, Graziella, De Luca, Michele
openaire +3 more sources
Characterisation of apoptotic responses in human keratinocytes expressnig alpha-6 integrin and CD44 [PDF]
, 2010 PhDa6 integrin has previously been proposed as a human keratinocyte stem cell markers. CD44-positive cells in epithelial tumours have been identified as potential cancer stem cells (CSCs) and display increased survival following chemotherapy ...
Wray, Helen
core +4 more sources
Primary Cilia in the Skin: Functions in Immunity and Therapeutic Potential
Frontiers in Cell and Developmental Biology, 2021 The skin is the biggest organ and provides a physical and immunological barrier against pathogen infection. The distribution of primary cilia in the skin of mice has been reported, but which cells in human skin have them has not, and we still know very ...
Manami Toriyama +5 more
doaj +1 more source
Acta Dermato-Venereologica, 2020 Although it is known that psoriatic dermal-derived mesenchymal stem cells (DMSCs) dysregulate keratinocyte proliferation, the biological activity profile of keratinocytes influenced by psoriatic DMSCs remain unknown. In the present study, we assessed the
Junqin Li +13 more
doaj +1 more source
Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion. [PDF]
, 2013 Desmosomes provide intercellular adhesive strength required for integrity of epithelial and some non-epithelial tissues. Within the epidermis, the cadherin-type adhesion molecules desmoglein (Dsg) 1-4 and desmocollin (Dsc) 1-3 build the adhesive core of ...
Bettina Kempf +23 more
core +2 more sources
Frontiers in Immunology, 2021 Rosacea is a common chronic inflammatory condition that mainly affects the central face. However, the molecular background of the normal central face and the transcriptional profiling and immune cell composition of rosacea lesions remain largely unknown.
Zhili Deng +41 more
doaj +1 more source
Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema
BMC Pulmonary Medicine, 2005 Background Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair. We hypothesized that excessive alveolar destruction observed in lung emphysema involves impaired expression of hepatocyte and keratinocyte ...
Marchal Joëlle +8 more
doaj +1 more source
Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes
Frontiers in Microbiology, 2020 Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as arboviruses, enteroviruses, herpes viruses, human papillomaviruses, or vaccinia virus.
Céline Chessa +9 more
doaj +1 more source
SAGE Open Medicine, 2016 Objectives: The composition of the medical costs incurred by people treated for basal cell and squamous cell carcinomas (hereafter keratinocyte cancers) is not adequately understood.
David Rowell +3 more
doaj +1 more source