Results 11 to 20 of about 108,825 (100)

Keratinocytes contribute to normal cold and heat sensation

eLife, 2020
Keratinocytes are the most abundant cell type in the epidermis, the most superficial layer of skin. Historically, epidermal-innervating sensory neurons were thought to be the exclusive detectors and transmitters of environmental stimuli.
Katelyn E Sadler, Francie Moehring, Cheryl L Stucky   +2 more
doaj   +1 more source

Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema

BMC Pulmonary Medicine, 2005
Background Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair. We hypothesized that excessive alveolar destruction observed in lung emphysema involves impaired expression of hepatocyte and keratinocyte ...
Marchal Joëlle, Leçon-Malas Véronique, Boutten Anne, Bonay Marcel, Soler Paul, Fournier Michel, Leseche Guy, Dehoux Monique, Crestani Bruno   +8 more
doaj   +1 more source

A comparison of the direct medical costs for individuals with or without basal or squamous cell skin cancer: A study from Australia

SAGE Open Medicine, 2016
Objectives: The composition of the medical costs incurred by people treated for basal cell and squamous cell carcinomas (hereafter keratinocyte cancers) is not adequately understood.
David Rowell, Louisa G Gordon, Catherine M Olsen, David C Whiteman   +3 more
doaj   +1 more source

Emerging roles of keratinocytes in nociceptive transduction and regulation

Frontiers in Molecular Neuroscience, 2022
Keratinocytes are the predominant block-building cells in the epidermis. Emerging evidence has elucidated the roles of keratinocytes in a wide range of pathophysiological processes including cutaneous nociception, pruritus, and inflammation ...
Xiaohan Xu, Catherine Yu, Catherine Yu, Catherine Yu, Li Xu, Jijun Xu, Jijun Xu, Jijun Xu   +7 more
doaj   +1 more source

Effect of cold atmospheric microwave plasma (CAMP) on wound healing in canine keratinocytes

Frontiers in Cell and Developmental Biology, 2023
Cutaneous wound healing is a biological process that occurs upon skin injury and involves different mechanisms to repair tissue damage. Improper healing or prolonged curation period of wound lesions may induce unpleasant complications.
Pattawika Lertpatipanpong, Chanin Sillapachaiyaporn, Chanin Sillapachaiyaporn, Garam Oh, Yeong-Hun Kang, Cheol-Yong Hwang, Seung Joon Baek   +6 more
doaj   +1 more source

Cell Type-Specific Transcriptome Profiling Reveals a Role for Thioredoxin During Tumor Initiation

Frontiers in Immunology, 2022
Neutrophils in the tumor microenvironment exhibit altered functions. However, the changes in neutrophil behavior during tumor initiation remain unclear.
Benjamin G. Korte, Benjamin G. Korte, Morgan A. Giese, Morgan A. Giese, Gayathri Ramakrishnan, Gayathri Ramakrishnan, Stella Ma, David Bennin, Julie Rindy, Colin N. Dewey, Anna Huttenlocher, Anna Huttenlocher   +11 more
doaj   +1 more source

Dsg2 Upregulation as a Rescue Mechanism in Pemphigus

Frontiers in Immunology, 2020
In pemphigus vulgaris (PV), autoantibodies directed against the desmosomal cadherin desmoglein (Dsg) 3 cause loss of intercellular adhesion. It is known that Dsg3 interactions are directly inhibited by autoantibody binding and that Dsg2 is upregulated in
Anna M. Sigmund, Letyfee S. Steinert, Desalegn T. Egu, Franziska C. Bayerbach, Jens Waschke, Franziska Vielmuth   +5 more
doaj   +1 more source

Photo-Protective and Anti-Inflammatory Effects of Antidesma thwaitesianum Müll. Arg. Fruit Extract against UVB-Induced Keratinocyte Cell Damage

Molecules, 2022
The main cause of most skin cancers is damage from UVB from sunlight, which penetrate the skin surface and induce inflammation. For this reason, this study aims to identify natural products with photo-protection properties and their mode of action by ...
Sutthibhon Natewong, Cholticha Niwaspragrit, Piyanee Ratanachamnong, Papavee Samatiwat, Poommaree Namchaiw, Yamaratee Jaisin   +5 more
doaj   +1 more source

Photobiomodulation Controls Keratinocytes Inflammatory Response through Nrf2 and Reduces Langerhans Cells Activation

Antioxidants, 2023
Photobiomodulation (PBM) is rapidly gaining traction as a valuable tool in dermatology for treating many inflammatory skin conditions using low levels of visible light or near-infrared radiation. However, the physiological regulatory pathways responsible
Sara Salman, Cyprien Guermonprez, Laurent Peno-Mazzarino, Elian Lati, Audrey Rousseaud, Lieve Declercq, Saadia Kerdine-Römer   +6 more
doaj   +1 more source

Subunit-Specific Reactivity of Autoantibodies Against Laminin-332 Reveals Direct Inflammatory Mechanisms on Keratinocytes

Frontiers in Immunology, 2021
Laminin-332 pemphigoid is a rare and severe autoimmune blistering disease, caused by IgG autoantibodies targeting laminin-332 in the dermal-epidermal basement zone.
Lei Bao, Jing Li, Farzan Solimani, Farzan Solimani, Dario Didona, Payal M. Patel, Xiaoguang Li, Hua Qian, Norito Ishii, Takashi Hashimoto, Takashi Hashimoto, Michael Hertl, Kyle T. Amber, Kyle T. Amber   +13 more
doaj   +1 more source