Results 91 to 100 of about 222,067 (306)

Rigidity of silicone substrates controls cell spreading and stem cell differentiation. [PDF]

, 2016
The dependences of spreading and differentiation of stem cells plated on hydrogel and silicone gel substrates on the rigidity and porosity of the substrates have recently been a subject of some controversy.
Groisman, Alex, Gutierrez, Edgar, Lee, Sin-Ae, Ronan, Edward, Tkachenko, Eugene, Vertelov, Grigory   +5 more
core   +2 more sources

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Staphylococcus epidermidis-induced Interleukin-1 Beta and Human Beta-defensin-2 Expression in Human Keratinocytes is Regulated by the Host Molecule A20 (TNFAIP3)

Acta Dermato-Venereologica, 2018
Staphylococcus epidermidis is an abundant skin commensal capable of activating cutaneous defense responses, such as induction of cytokines and antimicrobial peptides. To permanently colonize human skin and prevent inflammation S.
Maren Simanski, Anna-Sophie Erkens, Franziska Rademacher, Jürgen Harder   +3 more
doaj   +1 more source

The JNK Signaling Pathway in Inflammatory Skin Disorders and Cancer

Cells, 2020
The c-Jun N-terminal kinases (JNKs), with its members JNK1, JNK2, and JNK3, is a subfamily of (MAPK) mitogen-activated protein kinases. JNK signaling regulates a wide range of cellular processes, including cell proliferation, differentiation, survival ...
Manel B. Hammouda, Amy E. Ford, Yuan Liu, Jennifer Y. Zhang   +3 more
doaj   +1 more source

Visualisation of tissue kallikrein, kininogen and kinin receptors in human skin following trauma and in dermal diseases [PDF]

, 2004
During dermal injury and inflammation the serine proteases kallikreins cleave endogenous, multifunctional substrates (kininogens) to form bradykinin and kallidin.
Bhoola, Kanti D., Naidoo, Strinivasen, Neuhof, Christiane, Neuhof, Heinz, Sander, Christian, Schremmer-Danninger, Elisabeth, Snyman, Celia, Valeske, Klaus   +7 more
core   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Photobiomodulation of 450 nm Blue Light on Human Keratinocytes, Fibroblasts, and Endothelial Cells: An In Vitro and Transcriptomic Study on Cells Involved in Wound Healing and Angiogenesis

Biomedicines
Background: Blue light (BL) irradiation has been shown to induce photobiomodulation (PBM) in cells. Here, we investigate its influence on cell types involved in wound healing.
Jingbo Shao, Sophie Clément, Christoph Reissfelder, Patrick Téoule, Norbert Gretz, Feng Guo, Sabina Hajizada, Stefanie Uhlig, Katharina Mößinger, Carolina de la Torre, Carsten Sticht, Vugar Yagublu, Michael Keese   +12 more
doaj   +1 more source

HPV-18 transformed cells fail to arrest in G1 in response to quercetin treatment [PDF]

, 2005
Previous work with primary human keratinocytes demonstrated that quercetin, a potent mutagen found in high levels in bracken fern (Pteridium aquilinum), arrested cells in G1 with concomitant elevation of the cyclin-dependent kinase inhibitor (cdki ...
Alonso-Amelot, Beniston, Beniston, Bjeldanes, Cairney, Campo, Chang, Connolly, Cooper, Davies, de Villiers, Dell, Fazal, Galpin, Gillison, Hawley-Nelson, Hirayama, Ishidate, Jackson, Jones, M.S. Campo, Marliere, Nakayasu, O’Connor, Pecoraro, Pecoraro, Pennie, Plaumann, R.G. Beniston, Stanley, Suzuk, Suzuki, Syrjanen, Thierry, Togawa, Villalobos-Salazar, zur Hausen, zur Hausen   +37 more
core   +1 more source

Mechanically Robust MXene‐Metal Polyphenol Network Hybrid Interfaces for Multifunctional Protection of Keratin Fibers

Advanced Materials Interfaces, EarlyView.
Hair keratin fibers inevitably deteriorate under UV exposure, heat, and dryness. A robust composite coating assembles delaminated Ti3C2 MXene nanosheets onto keratin surfaces through biocompatible metal‐polyphenol networks of EGCG. This hybrid layer simultaneously screens UV, dissipates heat, reinforces mechanical strength, suppresses static charge ...
Juyeon Kang, Bomin Kim, Minkyoung Kim, Juyeon Park, Saehan Choi, Won Jun Lee, Heewon Kim, Yoonsung Nam, Jongwon Shim   +8 more
wiley   +1 more source

CONTRASTING EFFECTS OF AN MDM2 FUNCTIONAL POLYMORPHISM ON TUMOR PHENOTYPES [PDF]

, 2017
Cancer predisposition by the cooperation of genetic variants, such as single nucleotide polymorphisms (SNPs), may be of much greater significance to public health than previously appreciated.
Ortiz, Guadalupe J, IV
core   +2 more sources