Results 81 to 90 of about 222,067 (306)
PharmaceuticalsBackground: This study aimed to evaluate the anti-inflammatory and antioxidant effects of AS632 and AS633, two topical formulations composed of natural plant-derived ingredients, for potential use in arthritis therapy.
Thi Xoan Hoang +3 more
doaj +1 more source
In Vitro Comparative Skin Irritation Induced by Nano and Non-Nano Zinc Oxide
Nanomaterials, 2017 This study was designed to determine whether nano-sized ZnO has the potential to cause acute cutaneous irritation using cultured HaCaT keratinocytes and a human skin equivalent as in vitro models, compared to non-nanomaterials.
Maria Pilar Vinardell +3 more
doaj +1 more source
Melanoma in the Eyes of Mechanobiology
Frontiers in Cell and Developmental Biology, 2020 Skin is the largest organ of the human body with several important functions that can be impaired by injury, genetic or chronic diseases. Among all skin diseases, melanoma is one of the most severe, which can lead to death, due to metastization ...
M. Manuela Brás +9 more
doaj +1 more source
Stromal control of oncogenic traits expressed in response to the overexpression of GLI2, a pleiotropic oncogene. [PDF]
, 2009 Hedgehog signaling is often activated in tumors, yet it remains unclear how GLI2, a transcription factor activated by this pathway, acts as an oncogene. We show that GLI2 is a pleiotropic oncogene.
Albertson, DG +6 more
core
Role of FGFR2b expression and signaling in keratinocyte differentiation. Sequential involvement of PKCδ and PKCα [PDF]
, 2018 The tumor suppressor epithelial isoform of the fibroblast growth factor receptor 2 (FGFR2b) induces human keratinocyte early differentiation. Moreover, protein kinases C (PKCs) are known to regulate the differentiation program in several cellular ...
Belleudi, Francesca +4 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess +3 more
wiley +1 more source
Pemphigus—A Disease of Desmosome Dysfunction Caused by Multiple Mechanisms
Frontiers in Immunology, 2018 Pemphigus is a severe autoimmune-blistering disease of the skin and mucous membranes caused by autoantibodies reducing desmosomal adhesion between epithelial cells.
Volker Spindler, Jens Waschke
doaj +1 more source
Studies on the induction of pregnancy and the number of fetuses during pregnancy in rats
Journal of Animal Reproduction and Biotechnology, 2020 This study used adult wistar-based rats to observe the sexual cycle as a morphological characteristic of vaginal epithelial cells by vaginal smearing, and investigated the fetal number through mating with male rats of the same strain.
Seung-Hee Choi +6 more
doaj +1 more source
Switch from alpha v beta 5 to alpha v beta 6 integrin expression protects squamous cell carcinomas from anoikis [PDF]
, 2004 Stratified squamous epithelia express the alphavbeta5 integrin, but in squamous cell carcinomas (SCCs) there is down-regulation of alphavbeta5 and up-regulation of alphavbeta6.
Janes, SM, Watt, FM
core
Advanced Materials, EarlyView.This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi +12 more
wiley +1 more source