Results 71 to 80 of about 163,612 (298)

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Asymmetric Migration of Human Keratinocytes under Mechanical Stretch and Cocultured Fibroblasts in a Wound Repair Model [PDF]

, 2013
Keratinocyte migration during re-epithelization is crucial in wound healing under biochemical and biomechanical microenvironment. However, little is known about the underlying mechanisms whereby mechanical tension and cocultured fibroblasts or ...
Gao YX(高宇欣), Luo XD, Long M(龙勉), Liu XF(刘晓锋), Sun SJ(孙树津), Kang YY(康英永), Long, MA (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Natl Micrograv Lab, Beijing 100080, Peoples R China, Chen L, Chen J(陈娟), Lü DY(吕东媛), Huo B(霍波)   +10 more
core   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Eggplant Phenolamides: 2-Nonenal Scavenging and Skin Protection Against Aging Odor

Molecules
Eggplants are high in polyphenols, making them a powerful antioxidant food that is beneficial for health and has excellent anti-aging effects. As metabolism slows down with aging, lipid peroxides are generated, with 2-nonenal being the main cause of old ...
Hye Mi Kim, Ji Hoon Kim, Je-Seung Jeon, Chul Young Kim   +3 more
doaj   +1 more source

Keratinocyte growth factor: effects on keratinocytes and mechanisms of action

European Journal of Cell Biology, 2004
Keratinocyte growth factor (KGF) is a potent and specific mitogen for different types of epithelial cells, and it can protect these cells from various insults. Due to these properties, it is of particular importance for the repair of injured epithelial tissues, and it is currently therapeutically explored for the treatment of radiation- and ...
auf demKeller U, Krampert M, Kümin A, Braun S, Werner S   +4 more
openaire   +3 more sources

Use of in vitro human keratinocyte models to study the effect of cooling on chemotherapy drug-induced cytotoxicity [PDF]

, 2014
A highly distressing side-effect of cancer chemotherapy is chemotherapy-induced alopecia (CIA). Scalp cooling remains the only treatment for CIA, yet there is no experimental evidence to support the cytoprotective capacity of cooling. We have established
van den Hurk, Corina J., Komen, Manon M., Hussain, Omar, Dunnill, Christopher, Georgopoulos, Nikolaos T., Al-Tameemi, Wafaa, Collett, Andrew   +6 more
core   +1 more source

A Cryopreservation‐Based Supply Chain Strategy for Extrusion Bioprinting in Space

Advanced Materials Technologies, EarlyView.
Extrusion bioprinting on crewed space platforms requires a bioink that stays functional along the logistic chain. Here, cells and biomaterial ink travel separately, the cells cryopreserved and the ink cold stored, and are combined only minutes before printing.
Johannes Windisch, Max von Witzleben, Richard Frank Richter, Finn Dani, Constantin Greil, Sarah Duin, Anja Lode, Michael Gelinsky   +7 more
wiley   +1 more source

Refrigerated amniotic membrane maintains its therapeutic qualities for 48 hours

Frontiers in Bioengineering and Biotechnology
During wound healing, the migration of keratinocytes is critical for wound closure. The application of amniotic membrane (AM) on wounds with challenging contexts (e.g., chronification and diabetic foot ulcer) has proven very successful.
J. Stelling-Férez, J. Stelling-Férez, J. M. Puente-Cuadrado, V. Álvarez-Yepes, M. Alcaraz, M. Alcaraz, E. Tristante, I. Hernández-Mármol, I. Mompeán-Egea, A. M. García-Hernández, A. M. García-Hernández, F. J. Nicolás   +11 more
doaj   +1 more source

mSphere of Influence: Stromal Regulation of Epithelium Containing Viral Oncogenes

mSphere, 2019
Jason Bodily works in the field of tumor virology. In this mSphere of Influence article, he reflects on how “Inactivation of Rb in stromal fibroblasts promotes epithelial cell invasion” by Adam Pickard et al.
Jason Bodily
doaj   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source