Results 51 to 60 of about 74,447 (392)
Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]
20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
A Osaka+52 more
core +4 more sources
Feathers are hallmark avian integument appendages, although they were also present on theropods. They are composed of flexible corneous materials made of α- and β-keratins, but their genomic organization and their functional roles in feathers have not ...
C. Ng+14 more
semanticscholar +1 more source
Effects of the CDK-inhibitor CYC202 on p38 MAPK, ERK1/2 and c-Myc activities in papillomavirus type 16 E6- and E7-transformed human keratinocytes [PDF]
In the present study, we have investigated the effect of the chemical CDK-inhibitor CYC202 on E6 and E7-transformed keratinocytes, in which the function of the cellular cell cycle inhibitor p21Cip1 is abrogated by the viral genes.
Atanasova, Ganka+4 more
core +2 more sources
Clitoral development in the mouse and human. [PDF]
The goal of this report is (a) to provide the first detailed description of mouse clitoral development, and (b) to compare mouse and human clitoral development.
Baskin, Laurence+4 more
core +1 more source
Isolation and primary cultures of human intrahepatic bile ductular epithelium [PDF]
A technique for the isolation of human intrahepatic bile ductular epithelium, and the establishment of primary cultures using a serum- and growth-factor-supplemented medium combined with a connective tissue substrata is described.
A. E. Sirica+24 more
core +1 more source
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Expression of cytokeratins 5/6 and cytokeratin 17 in invasive breast carcinoma [PDF]
Background/Aim. Cytokeratins (CK) 5/6 and 17, myoepithelial markers, are also expressed in a proportion of breast carcinomas. Breast carcinomas expressing basal epithelium cytokeratins constitute a tumor subgroup that shows common but heterogeneous ...
Ivković-Kapicl Tatjana+4 more
doaj +1 more source
Regional variation in the flexural properties of the equine hoof wall [PDF]
The equine hoof wall is a hard, keratinous structure that transmits forces generated when the hoof connects the ground to the skeleton of the horse. During locomotion the hoof capsule is known to deform, resulting in an inward curvature of the dorsal ...
A M Goodman+23 more
core +1 more source
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Rational design of water‐soluble, homotypic keratins self‐assembly with enhanced bioactivities
Recombinant keratins possess strong hemostatic and wound healing properties but suffer from poor water solubility that restricts their bioactivities in biomedical applications. Herein, we report the rational design and synthesis of water‐soluble keratins
Jie Chen+8 more
doaj +1 more source