Results 1 to 10 of about 25,295 (209)
Impact of vaginal microbiota on the clinical efficacy and long-term recurrence of ketoconazole suppositories in treating severe vulvovaginal candidiasis: a secondary analysis of a multicentre randomised trial [PDF]
Frontiers in Cellular and Infection MicrobiologyObjectiveTo evaluate whether baseline vaginal-microbiota status influences the clinical cure rate and 30-day mycological recurrence of severe VVC after 6-day intravaginal ketoconazole therapy compared with miconazole nitrate.MethodsA prospective ...
Lan Mi, Dai Zhang
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مجلة علوم ذي قار, 2019 This study was performance to investigate the effect of over doses(high dose and long term) of antifungal ketoconazole on body weight, liver weight, Biochemical parameters (ALP, AST and ALT enzymes, as well as total protein and cholesterol ...
حسن عباس
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Indonesian Journal of Pharmacy, 2021 The use of radiopharmaceuticals for infection detection has gained increasing attention for their application in nuclear medicine. The administration of [99mTc]Tc-ketoconazole may altere pharmacological aspects including interaction data with some ...
Ahmad Kurniawan +4 more
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Dual effects of ketoconazole cis-enantiomers on CYP3A4 in human hepatocytes and HepG2 Cells. [PDF]
PLoS ONE, 2014 Antifungal drug ketoconazole causes severe drug-drug interactions by influencing gene expression and catalytic activity of major drug-metabolizing enzyme cytochrome P450 CYP3A4.
Aneta Novotná +6 more
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The combination of amoxicillin-clavulanic acid and ketoconazole in the treatment of Madurella mycetomatis eumycetoma and Staphylococcus aureus co-infection. [PDF]
PLoS Neglected Tropical Diseases, 2014 Eumycetoma is a chronic progressive disabling and destructive inflammatory disease which is commonly caused by the fungus Madurella mycetomatis. It is characterized by the formation of multiple discharging sinuses.
Najwa A Mhmoud +3 more
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The Effect of Insulin induced Hypoglycemia on ketoconazole Hepatototxicity in Rabbit [PDF]
The Medical Journal of Basrah University, 2015 Background: Hypoglycemia is one of the most common side effect of insulin treatment, it affect liver and can potentiate ketoconazole toxicity. Objectives: To measure effect of ketoconazole on liver enzymes, hypoglycemic oxidative stress and to evaluate
Nabeel A.J.Ali, Riyad H. Zayer Anaed
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Acta Veterinaria Scandinavica, 2021 Background Ketoconazole, an antifungal agent, adversely affects spermatogenesis in rodents, but knowledge on adverse effects of prolonged administration of ketoconazole on the fertility of male dogs is lacking.
Anna Domosławska, Sławomir Zduńczyk
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Ketoconazole inhibits the cellular uptake of anandamide via inhibition of FAAH at pharmacologically relevant concentrations. [PDF]
PLoS ONE, 2014 The antifungal compound ketoconazole has, in addition to its ability to interfere with fungal ergosterol synthesis, effects upon other enzymes including human CYP3A4, CYP17, lipoxygenase and thromboxane synthetase.
Emmelie Björklund +3 more
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Al-Azhar Assiut Medical Journal, 2022 Background and aim Pityriasis versicolor is a common chronic superficial fungal infection that manifests during or after puberty in hot humid temperatures.
Khaled M Tawfik +2 more
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