Results 21 to 30 of about 25,295 (209)
Spectrophotometric method for the determination of ketoconazole based on amplification reactions
Journal of Pharmaceutical Analysis, 2012 This paper describes a sensitive spectrophotometric method developed for determination of Ketoconazole (KC) in tablets based on amplification reactions. Ketoconazole was oxidized with periodate, resulting in formation of KC2+ and iodate ions.
Shaligram S. Rane, P. Padmaja
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Drug Analytical Research, 2020 We developed and validated a stability-indicating method for the simultaneous determination of allopurinol and ketoconazole in the pharmaceutical form of capsules. A Dionex® liquid chromatograph equipped with a diode array detector (DAD) and InertSustain®
Patrícia Espinosa dos Santos +3 more
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Frontiers in Endocrinology, 2022 IntroductionTwenty-four-hour urinary free cortisol (24h-UFC) is the most used test for follow-up decision-making in patients with Cushing syndrome (CS) under medical treatment.
Arturo Vega-Beyhart +17 more
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A novel formulation of ketoconazole entrapped in alginate with anionic polymer beads for solubility enhancement: Preparation and characterization [PDF]
Pharmacia, 2023 Ketoconazole has low solubility in intestinal pH, whereas drug absorption is largest in the small intestine, which can reduce the bioavailability of the drug.
Viviane Annisa +3 more
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Multifactorial Mechanisms of Tolerance to Ketoconazole in Candida albicans
Microbiology Spectrum, 2021 Candida albicans is a prevalent opportunistic human fungal pathogen for which treatment is limited to only four main classes of antifungal drugs, with the azole and echinocandin classes being used most frequently.
Yi Xu +6 more
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Journal of Toxicology, 2017 Oral ketoconazole was recently the subject of regulatory safety warnings because of its association with increased risk of inducing hepatic injury. However, the relative hepatotoxicity of antifungal agents has not been clearly established.
Star Khoza, Ishmael Moyo, Denver Ncube
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Microbiologia Medica, 2021 Background Increase in resistance to conventional antifungals renders the need for antifungal sensitivity testing in Dermatophytes. The present study aimed at determining the prevalence of dermatophytic infections and their susceptibility ...
Dharmendra Singh +4 more
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Enhanced Interaction between Warfarin and High-Dose Ketoconazole: A Case Report
Case Reports in Medicine, 2009 This case describes the increased anticoagulation effect associated with the use of high-dose ketoconazole. A 59-year-old man treated with warfarin for aortic valve replacement was prescribed high-dose ketoconazole and hydrocortisone for the treatment ...
Cynthia A. Jackevicius, Mannhu N. Ton
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Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer
British Journal of Clinical Pharmacology, EarlyView.Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog +8 more
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Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks
British Journal of Clinical Pharmacology, EarlyView.The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou +2 more
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