Results 31 to 40 of about 57,314 (316)
A novel formulation of ketoconazole entrapped in alginate with anionic polymer beads for solubility enhancement: Preparation and characterization [PDF]
Pharmacia, 2023 Ketoconazole has low solubility in intestinal pH, whereas drug absorption is largest in the small intestine, which can reduce the bioavailability of the drug.
Viviane Annisa +3 more
doaj +3 more sources
Effects of Ketoconazole and Rifampicin on the Pharmacokinetics of Nintedanib in Healthy Subjects
European journal of drug metabolism and pharmacokinetics, 2018 Nintedanib is a substrate for p-glycoprotein which can impact bioavailability. We investigated the effects of ketoconazole, a p-glycoprotein inhibitor, and rifampicin, a p-glycoprotein inducer, on the pharmacokinetics of nintedanib.
D. Luedtke +4 more
semanticscholar +1 more source
Multifactorial Mechanisms of Tolerance to Ketoconazole in Candida albicans
Microbiology Spectrum, 2021 Candida albicans is a prevalent opportunistic human fungal pathogen for which treatment is limited to only four main classes of antifungal drugs, with the azole and echinocandin classes being used most frequently.
Yi Xu +6 more
doaj +1 more source
Journal of Microbiology and Biotechnology, 2018 Malassezia pachydermatis is a commensal yeast found on the skin of dogs. However, M. pachydermatis is also considered an opportunistic pathogen and is associated with various canine skin diseases including otitis externa and atopic dermatitis, which ...
Minchul Kim +5 more
semanticscholar +1 more source
Quantification of voriconazole in plasma by liquid chromatography-tandem mass spectrometry [PDF]
, 2005 A convenient liquid chromatography-tandem mass spectrometry method for the quantification of the triazole antifungal agent voriconazole in plasma samples is described. Fenbuconazole is used as an internal standard.
Boyd +16 more
core +1 more source
Trakya University Journal of Natural Sciences, 2020 Application of combination studies with essential oils and standard antifungal drugs may reduce adverse effects of synthetic drugs and serve as alternative approach against various pathologies including candidiasis.
Fatih Demirci +3 more
doaj +1 more source
Microbiologia Medica, 2021 Background Increase in resistance to conventional antifungals renders the need for antifungal sensitivity testing in Dermatophytes. The present study aimed at determining the prevalence of dermatophytic infections and their susceptibility ...
Dharmendra Singh +4 more
doaj +1 more source
Enhanced Interaction between Warfarin and High-Dose Ketoconazole: A Case Report
Case Reports in Medicine, 2009 This case describes the increased anticoagulation effect associated with the use of high-dose ketoconazole. A 59-year-old man treated with warfarin for aortic valve replacement was prescribed high-dose ketoconazole and hydrocortisone for the treatment ...
Cynthia A. Jackevicius, Mannhu N. Ton
doaj +1 more source
Study The Effect of Ketoconazole and Vitamin E on Some Arabi Ram Sperm Characteristics [PDF]
Basrah Journal of Veterinary Research, 1970 Experiment aims to investigate the effect of ketoconazole on certain sperm characteristic of Arabi rams .fifteen adult rams were randomly assigned in 3 groups, 5 animals in each group which treated daily as the ...
Khairi G. Alrikabi
doaj +1 more source
Edoxaban drug–drug interactions with ketoconazole, erythromycin, and cyclosporine
British Journal of Clinical Pharmacology, 2016 Aims Edoxaban, a novel factor Xa inhibitor, is a substrate of cytochrome P450 3 A4 (CYP3A4) and the efflux transporter P‐glycoprotein (P‐gp). Three edoxaban drug–drug interaction studies examined the effects of P‐gp inhibitors with varying degrees of ...
D. Parasrampuria +5 more
semanticscholar +1 more source