Results 61 to 70 of about 25,295 (209)

Ketoconazole induces reversible antifungal drug tolerance mediated by trisomy of chromosome R in Candida albicans

open access: yesFrontiers in Microbiology
BackgroundThe emergence of tolerance to antifungal agents in Candida albicans complicates the treatment of fungal infections. Understanding the mechanisms underlying this tolerance is crucial for developing effective therapeutic strategies.ObjectiveThis ...
Lijun Zheng   +3 more
doaj   +1 more source

Hydrogel of Ketoconazole and PAMAM Dendrimers: Formulation and Antifungal Activity

open access: yesMolecules, 2012
Ketoconazole (KET), an imidazole derivative with well-known antifungal properties, is lipophilic and practically insoluble in water, therefore its clinical use has some practical disadvantages.
Elzbieta Tryniszewska   +4 more
doaj   +1 more source

Treatment of Reactive Histiocytosis With Oclacitinib: A Retrospective Case Series of 10 Dogs

open access: yesVeterinary Dermatology, EarlyView.
Background: Canine reactive histiocytosis is a proliferative disorder of activated interstitial dendritic cells with cutaneous and systemic forms. An immune‐mediated aetiology is likely, and systemic immunomodulatory agents such as corticosteroids, tetracycline/niacinamide, ciclosporin, azathioprine and leflunomide have been employed for its management.
Christine L. Cain   +2 more
wiley   +1 more source

Effect of permeation enhancers on the penetration mechanism of transfersomal gel of ketoconazole

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2012
The aim of the present research work was to investigate the potential of transfersome formulations for transdermal delivery of Ketoconazole (KTZ). KTZ is a broad-spectrum antifungal agent that is active against a wide variety of fungi and yeasts.
Reshmy Rajan, Deepa T Vasudevan
doaj   +1 more source

Silk Fibroin Hydrogel-Assisted Controlled Release of Antifungal Drug Ketoconazole

open access: diamond, 2023
Tomal Chandro Roy   +3 more
openalex   +2 more sources

Effects of Ketoconazole On Clinical Recovery In Central Serous Chorioretinopathy [PDF]

open access: green, 2021
Yodpong Chantarasorn   +3 more
openalex   +1 more source

Efficacy and Tolerability of Metyrapone in Mild Autonomous Cortisol Secretion: Real‐World Findings From Clinical Practice

open access: yesClinical Endocrinology, Volume 104, Issue 3, Page 215-221, March 2026.
ABSTRACT Objective Mild autonomous cortisol secretion (MACS) is associated with increased cardiometabolic risk factors including hypertension, type 2 diabetes and dyslipidaemia. By using evening doses of metyrapone, a short‐acting 11‐β hydroxylase inhibitor, it has been shown that it is possible to reset the abnormal circadian cortisol rhythm in MACS ...
Simon Berry   +3 more
wiley   +1 more source

Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel   +9 more
wiley   +1 more source

Synergistic Antifungal Effects of Honokiol and Fluconazole Against Oral Candida: Implications for Managing Drug‐Resistant Infections

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Objectives Antifungal drug resistance poses a major challenge in treating oral Candida infections. This study aimed to evaluate the antifungal activity of Honokiol, alone and combined with Fluconazole, against oral Candida isolates, and to investigate its mechanism of action via ergosterol biosynthesis inhibition and cell wall disruption ...
Maribasappa Karched   +2 more
wiley   +1 more source

Ketoconazole Allergy [PDF]

open access: yesClinics, 2009
Ensina, Luis Felipe   +4 more
openaire   +4 more sources

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