Results 1 to 10 of about 29,891 (282)

Ketone Bodies Preserve Mitochondria Through Epigenetics∗ [PDF]

JACC: Basic to Translational Science, 2023
[Figure: see text]
Risa Mukai, PhD, Junichi Sadoshima, MD, PhD   +1 more
doaj   +4 more sources

Regulation of adult stem cell function by ketone bodies [PDF]

Frontiers in Cell and Developmental Biology, 2023
Adult stem cells play key roles in tissue homeostasis and regeneration. Recent evidence suggests that dietary interventions can significantly impact adult stem cell function. Some of these effects depend on ketone bodies. Adult stem cells could therefore
Ole Emil Andersen, Ole Emil Andersen, Jens Vase Poulsen, Jean Farup, Jean Farup, Antoine de Morree   +5 more
doaj   +2 more sources

Ketone Bodies in Cardiovascular Disease [PDF]

JACC: Basic to Translational Science
Summary: Evidence for the potential of ketone bodies (KBs) in the treatment of cardiovascular disease is growing rapidly. In addition to serving as sources of myocardial fuel, KBs exert an array of pleiotropic activities via multiple mechanisms.
Azariyas A. Challa, MD, PhD, Bradford G. Hill, PhD, Matthew A. Nystoriak, PhD, Kara R. Gouwens, BS, Dinesh K. Kalra, MD   +4 more
doaj   +2 more sources

Ketone Bodies, Potential Therapeutic Uses [PDF]

IUBMB Life, 2001
AbstractKetosis, meaning elevation of D‐ β‐hydroxybutyrate ( R ‐3‐hydroxybutyrate) and acetoacetate, has been central to starving man's survival by providing nonglucose substrate to his evolutionarily hypertrophied brain, sparing muscle from destruction for glucose synthesis.
Richard L. Veech, Britton Chance, Yoshihiro Kashiwaya, Henry A. Lardy, George F. Cahill   +4 more
openalex   +4 more sources

Oxaloacetate and Ketone Bodies Synergistically Promote Myoblast Differentiation in L6 Cells [PDF]

Molecules
Malnutrition and aging are major factors that inhibit myoblast differentiation, leading to a decline in muscle function and contributing to sarcopenia development.
Yuji Onuki, Naoki Nanashima, Yutaro Sasaki, Akiko Kojima-Yuasa, Toshio Norikura   +4 more
doaj   +2 more sources

Ketone Bodies Mediate Antiseizure Effects

Pediatric Neurology Briefs, 2015
Investigators from The Barrow Neurological Institute, Creighton University, University of Kentucky and the University of Calgary Faculty of Medicine investigated the effect of ketone bodies and the ketogenic diet on epileptic Kcna1-null mice.
Jena M. Krueger, Douglas R. Nordli
doaj   +4 more sources

Early Detection of Elevated Ketone Bodies in Type 1 Diabetes Using Insulin and Glucose Dynamics Across Age Groups: Model Development Study [PDF]

JMIR Diabetes
BackgroundDiabetic ketoacidosis represents a significant and potentially life-threatening complication of diabetes, predominantly observed in individuals with type 1 diabetes (T1D).
Simon Cichosz, Clara Bender
doaj   +2 more sources

Elevation of hypothalamic ketone bodies induces a decrease in energy expenditures and an increase risk of metabolic disorder [PDF]

Molecular Metabolism
Objective: Ketone bodies (such as β-hydroxybutyrate or BHB) have been recently proposed as signals involved in brain regulation of energy homeostasis and obesity development. However, the precise role of ketone bodies sensing by the brain, and its impact
Lionel Carneiro, Rocco Bernasconi, Adriano Bernini, Cendrine Repond, Luc Pellerin   +4 more
doaj   +2 more sources

Ketone Bodies after Cardiac Arrest: A Narrative Review and the Rationale for Use [PDF]

Cells
Cardiac arrest survivors suffer the repercussions of anoxic brain injury, a critical factor influencing long-term prognosis. This injury is characterised by profound and enduring metabolic impairment.
Filippo Annoni, Elisa Gouvea Bogossian, Lorenzo Peluso, Fuhong Su, Anthony Moreau, Leda Nobile, Stefano Giuseppe Casu, Elda Diletta Sterchele, Lorenzo Calabro, Michele Salvagno, Mauro Oddo, Fabio Silvio Taccone   +11 more
doaj   +2 more sources

SAT-274 Ketone Bodies Impact Immune Cell Metabolism [PDF]

J Endocr Soc
Rachael Klein
europepmc   +3 more sources