Regulation of adult stem cell function by ketone bodies [PDF]
Frontiers in Cell and Developmental Biology, 2023 Adult stem cells play key roles in tissue homeostasis and regeneration. Recent evidence suggests that dietary interventions can significantly impact adult stem cell function. Some of these effects depend on ketone bodies. Adult stem cells could therefore
Ole Emil Andersen +5 more
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Ketone Bodies in Cardiovascular Disease [PDF]
JACC: Basic to Translational ScienceSummary: Evidence for the potential of ketone bodies (KBs) in the treatment of cardiovascular disease is growing rapidly. In addition to serving as sources of myocardial fuel, KBs exert an array of pleiotropic activities via multiple mechanisms.
Azariyas A. Challa, MD, PhD +4 more
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Oxaloacetate and Ketone Bodies Synergistically Promote Myoblast Differentiation in L6 Cells [PDF]
MoleculesMalnutrition and aging are major factors that inhibit myoblast differentiation, leading to a decline in muscle function and contributing to sarcopenia development.
Yuji Onuki +4 more
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Early Detection of Elevated Ketone Bodies in Type 1 Diabetes Using Insulin and Glucose Dynamics Across Age Groups: Model Development Study [PDF]
JMIR DiabetesBackgroundDiabetic ketoacidosis represents a significant and potentially life-threatening complication of diabetes, predominantly observed in individuals with type 1 diabetes (T1D).
Simon Cichosz, Clara Bender
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Elevation of hypothalamic ketone bodies induces a decrease in energy expenditures and an increase risk of metabolic disorder [PDF]
Molecular MetabolismObjective: Ketone bodies (such as β-hydroxybutyrate or BHB) have been recently proposed as signals involved in brain regulation of energy homeostasis and obesity development. However, the precise role of ketone bodies sensing by the brain, and its impact
Lionel Carneiro +4 more
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Ketone Bodies after Cardiac Arrest: A Narrative Review and the Rationale for Use [PDF]
CellsCardiac arrest survivors suffer the repercussions of anoxic brain injury, a critical factor influencing long-term prognosis. This injury is characterised by profound and enduring metabolic impairment.
Filippo Annoni +11 more
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Ketone Bodies Preserve Mitochondria Through Epigenetics∗ [PDF]
JACC: Basic to Translational Science, 2023 Risa Mukai, PhD +1 more
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Editorial: Ketone bodies: friend or foe? [PDF]
Frontiers in EndocrinologyFelix Sternberg +5 more
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Urine ketone bodies and adverse outcomes in patients with acute ischemic stroke or TIA
Atherosclerosis Plus, 2022 Background and aims: Urine ketone bodies have been considered as predictors of stroke in diabetic patients, however, the role of urine ketone bodies in the prognosis of stroke has not been investigated well.
Anxin Wang +7 more
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Beta-Hydroxybutyrate: A Dual Function Molecular and Immunological Barrier Function Regulator
Frontiers in Immunology, 2022 Ketone bodies are crucial intermediate metabolites widely associated with treating metabolic diseases. Accumulating evidence suggests that ketone bodies may act as immunoregulators in humans and animals to attenuate pathological inflammation through ...
Jiancheng Qi +11 more
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