Editorial: Ketone bodies: friend or foe? [PDF]
Frontiers in EndocrinologyFelix Sternberg +5 more
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Ketogenic Diet and Ketone Bodies as Clinical Support for the Treatment of SARS-CoV-2—Review of the Evidence [PDF]
Viruses, 2023 One of the proposed nutritional therapies to support drug therapy in COVID-19 is the use of a ketogenic diet (KD) or ketone bodies. In this review, we summarized the evidence from tissue, animal, and human models and looked at the mechanisms of action of
Izabela Bolesławska +3 more
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Early Detection of Elevated Ketone Bodies in Type 1 Diabetes Using Insulin and Glucose Dynamics Across Age Groups: Model Development Study [PDF]
JMIR DiabetesBackgroundDiabetic ketoacidosis represents a significant and potentially life-threatening complication of diabetes, predominantly observed in individuals with type 1 diabetes (T1D).
Simon Cichosz, Clara Bender
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Ketone Bodies in Neurological Diseases: Focus on Neuroprotection and Underlying Mechanisms
Frontiers in Neurology, 2019 There is growing evidence that ketone bodies, which are derived from fatty acid oxidation and usually produced in fasting state or on high-fat diets have broad neuroprotective effects.
Huajun Yang +14 more
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Ketogenic diet versus ketoacidosis: what determines the influence of ketone bodies on neurons?
Neural Regeneration Research, 2018 Glucose is the main energy substrate for neurons, however, at certain conditions, e.g. in starvation, these cells could also use ketone bodies. This approach is used in clinical conditions as the ketogenic diet.
Sergei V Fedorovich +2 more
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Ketone Bodies Mediate Antiseizure Effects
Pediatric Neurology Briefs, 2015 Investigators from The Barrow Neurological Institute, Creighton University, University of Kentucky and the University of Calgary Faculty of Medicine investigated the effect of ketone bodies and the ketogenic diet on epileptic Kcna1-null mice.
Jena M. Krueger, Douglas R. Nordli
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Exploring the role of ketone bodies in the diagnosis and treatment of psychiatric disorders [PDF]
Frontiers in Psychiatry, 2023 In recent times, advances in the field of metabolomics have shed greater light on the role of metabolic disturbances in neuropsychiatric conditions. The following review explores the role of ketone bodies and ketosis in both the diagnosis and treatment ...
Naomi Elyse Omori +3 more
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Ketone Body Metabolism in the Ischemic Heart [PDF]
Frontiers in Cardiovascular Medicine, 2021 Ketone bodies have been identified as an important, alternative fuel source in heart failure. In addition, the use of ketone bodies as a fuel source has been suggested to be a potential ergogenic aid for endurance exercise performance.
Stephen C. Kolwicz
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Elevation of hypothalamic ketone bodies induces a decrease in energy expenditures and an increase risk of metabolic disorder [PDF]
Molecular MetabolismObjective: Ketone bodies (such as β-hydroxybutyrate or BHB) have been recently proposed as signals involved in brain regulation of energy homeostasis and obesity development. However, the precise role of ketone bodies sensing by the brain, and its impact
Lionel Carneiro +4 more
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Ketone Bodies after Cardiac Arrest: A Narrative Review and the Rationale for Use [PDF]
CellsCardiac arrest survivors suffer the repercussions of anoxic brain injury, a critical factor influencing long-term prognosis. This injury is characterised by profound and enduring metabolic impairment.
Filippo Annoni +11 more
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