Results 11 to 20 of about 29,891 (282)

Mendelian randomization study on the association of circulating ketone bodies with lung cancer and respiratory diseases. [PDF]

Sci Rep
Tang X, Zhuang H, Yu H.
europepmc   +3 more sources

Editorial: Ketone bodies: friend or foe? [PDF]

Frontiers in Endocrinology
Felix Sternberg, Felix Sternberg, Mitsunori Nomura, Min Xie, Kalina Duszka, Kalina Duszka   +5 more
doaj   +2 more sources

Urine ketone bodies and adverse outcomes in patients with acute ischemic stroke or TIA

Atherosclerosis Plus, 2022
Background and aims: Urine ketone bodies have been considered as predictors of stroke in diabetic patients, however, the role of urine ketone bodies in the prognosis of stroke has not been investigated well.
Anxin Wang, Xue Tian, Yingting Zuo, Qin Xu, Xia Meng, Pan Chen, Hao Li, Yongjun Wang   +7 more
doaj   +1 more source

Beta-Hydroxybutyrate: A Dual Function Molecular and Immunological Barrier Function Regulator

Frontiers in Immunology, 2022
Ketone bodies are crucial intermediate metabolites widely associated with treating metabolic diseases. Accumulating evidence suggests that ketone bodies may act as immunoregulators in humans and animals to attenuate pathological inflammation through ...
Jiancheng Qi, Linli Gan, Jing Fang, Jizong Zhang, Xin Yu, Hongrui Guo, Dongjie Cai, Hengmin Cui, Liping Gou, Junliang Deng, Zhisheng Wang, Zhicai Zuo   +11 more
doaj   +1 more source

Measuring ketone bodies for the monitoring of pathologic and therapeutic ketosis

Obesity Science & Practice, 2021
Background The ketone bodies β‐hydroxybutyrate (BOHB) and acetone are generated as a byproduct of the fat metabolism process. In healthy individuals, ketone body levels are ∼0.1 mM for BOHB and ∼1 part per million for breath acetone (BrAce). These levels
Joseph C. Anderson, Samer G. Mattar, Frank L. Greenway, Richard J. Lindquist   +3 more
doaj   +1 more source

Ketone body oxidation increases cardiac endothelial cell proliferation

EMBO Molecular Medicine, 2022
Blood vessel formation is dependent on metabolic adaption in endothelial cells. Glucose and fatty acids are essential substrates for ATP and biomass production; however, the metabolism of other substrates remains poorly understood.
Eva‐Maria Weis, Patrycja Puchalska, Alisa B Nelson, Jacqueline Taylor, Iris Moll, Sana S Hasan, Matthias Dewenter, Marco Hagenmüller, Thomas Fleming, Gernot Poschet, Agnes Hotz‐Wagenblatt, Johannes Backs, Peter A Crawford, Andreas Fischer   +13 more
doaj   +1 more source

Cardiac ketone body metabolism

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2020
The ketone bodies, d-β-hydroxybutyrate and acetoacetate, are soluble 4-carbon compounds derived principally from fatty acids, that can be metabolised by many oxidative tissues, including heart, in carbohydrate-depleted conditions as glucose-sparing energy substrates.
Azrul, Abdul Kadir, Kieran, Clarke, Rhys D, Evans   +2 more
openaire   +3 more sources

Ketogenic effects of medium chain triglycerides containing formula and its correlation to breath acetone in healthy volunteers: a randomized, double-blinded, placebo-controlled, single dose-response study

Frontiers in Nutrition, 2023
The efficacy of low-carbohydrate, high-fat diets, such as ketogenic diets, for cancer patients is of research interest. We previously demonstrated the efficacy of the ketogenic diet in a case study in which medium-chain triglycerides (MCTs) or MCT ...
Kentaro Nakamura, Keisuke Hagihara, Naoko Nagai, Ryuichiro Egashira, Mariko Takeuchi, Mai Nakano, Hitomi Saito, Misaki Moriguchi, Satoko Tonari, Hisako Fujii, Akimitsu Miyake, Yusuke Omae, Kinya Ashida   +12 more
doaj   +1 more source

Ketone bodies in epilepsy [PDF]

Journal of Neurochemistry, 2012
J. Neurochem.(2012)121, 28–35.AbstractSeizures that are resistant to standard medications remain a major clinical problem. One underutilized option for patients with medication‐resistant seizures is the high‐fat, low‐carbohydrate ketogenic diet. The diet received its name based on the observation that patients consuming this diet produce ketone bodies (
Melanie A, McNally, Adam L, Hartman
openaire   +2 more sources

Ketone Bodies in the Brain Beyond Fuel Metabolism: From Excitability to Gene Expression and Cell Signaling

Frontiers in Molecular Neuroscience, 2021
Ketone bodies are metabolites that replace glucose as the main fuel of the brain in situations of glucose scarcity, including prolonged fasting, extenuating exercise, or pathological conditions such as diabetes.
Darío García-Rodríguez, Alfredo Giménez-Cassina   +1 more
doaj   +1 more source