Results 21 to 30 of about 29,891 (282)
Viruses, 2023 One of the proposed nutritional therapies to support drug therapy in COVID-19 is the use of a ketogenic diet (KD) or ketone bodies. In this review, we summarized the evidence from tissue, animal, and human models and looked at the mechanisms of action of
Izabela Bolesławska +3 more
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Ketone bodies: from enemy to friend and guardian angel
BMC Medicine, 2021 During starvation, fasting, or a diet containing little digestible carbohydrates, the circulating insulin levels are decreased. This promotes lipolysis, and the breakdown of fat becomes the major source of energy.
Hubert Kolb +5 more
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Archives of Medical Science – Atherosclerotic Diseases, 2021 Ketone bodies are low chain organic substances with four carbon atoms, with β-hydroxybutyric acid and acetone being the main ketone bodies in blood circulation. Under physiological conditions their levels are low while during conditions of oxidative stress, such as exercise, fasting state and acute illness, ketone body levels are increased.
Papazafiropoulou, Athanasia K. +2 more
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Molecular Metabolism, 2021 Objective: Throughout the last decade, interest has intensified in intermittent fasting, ketogenic diets, and exogenous ketone therapies as prospective health-promoting, therapeutic, and performance-enhancing agents.
David B. Stagg +6 more
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Ketogenic diet versus ketoacidosis: what determines the influence of ketone bodies on neurons?
Neural Regeneration Research, 2018 Glucose is the main energy substrate for neurons, however, at certain conditions, e.g. in starvation, these cells could also use ketone bodies. This approach is used in clinical conditions as the ketogenic diet.
Sergei V Fedorovich +2 more
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Ketone bodies as signaling metabolites [PDF]
Trends in Endocrinology & Metabolism, 2014 Traditionally, the ketone body β-hydroxybutyrate (βOHB) has been looked upon as a carrier of energy from liver to peripheral tissues during fasting or exercise. However, βOHB also signals via extracellular receptors and acts as an endogenous inhibitor of histone deacetylases (HDACs). These recent findings support a model in which βOHB functions to link
John C, Newman, Eric, Verdin
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Determination of 14C radioactivity in ketone bodies: a new, simplified method and its validation.
Journal of Lipid Research, 1980 A rapid and reproducible method for the assay of 14C radioactivity in ketone bodies is described, based on the heat lability of acetoacetate and the ability of beta-hydroxybutyrate to quantitatively bind to and elute from an ion exchange resin. Potential
J M Miles +3 more
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Food Chemistry: Molecular Sciences, 2021 Ketogenic diets consist of low carbohydrate/high fat, shifting energy reliance from glucose to ketone bodies. Ketone diester supplement to a standard diet (ketone ester) increases ketone bodies by adding a substance without altering other consumed foods.
LT Claire M. Modica +6 more
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Journal of Obesity & Metabolic Syndrome, 2020 Background : Ketone bodies are a well-known metabolite from the utilization of fatty acids in the fasting state. Some studies have demonstrated the metabolic benefits of urinary ketones in a specific population in whom ketone bodies were detected ...
Jong-Min Han, Nam-Seok Joo
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The Ketone Bridge Between the Heart and the Bladder: How Fast Should We Go? [PDF]
International Neurourology JournalMetabolic syndrome (MS) is associated with both cardiovascular and bladder dysfunction. Insulin resistance (IR) and central obesity, in particular, are the main risk factors. In these patients, vicious pathological cycles exacerbate abnormal carbohydrate
Gabriel Faria-Costa +8 more
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