Very‐low‐carbohydrate diet enhances human T‐cell immunity through immunometabolic reprogramming
EMBO Molecular Medicine, 2021 Very‐low‐carbohydrate diet triggers the endogenous production of ketone bodies as alternative energy substrates. There are as yet unproven assumptions that ketone bodies positively affect human immunity.
Simon Hirschberger +14 more
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Measurement of β-hydroxybutyrate in cats with nonketotic diabetes mellitus, diabetic ketosis, and diabetic ketoacidosis [PDF]
, 2011 Diabetic ketoacidosis (DKA) is a life-threatening complication of diabetes mellitus (DM). The standard method of detection of ketone bodies is the dipstick method, which detects semiquantitatively acetoacetate, but not β-hydroxybutyrate (β-HB).
Kohn, Barbara +2 more
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Blood Ketone Bodies and Breath Acetone Analysis and Their Correlations in Type 2 Diabetes Mellitus
Diagnostics, 2019 Analysis of volatile organic compounds in the breath for disease detection and monitoring has gained momentum and clinical significance due to its rapid test results and non-invasiveness, especially for diabetes mellitus (DM). Studies have suggested that
V. Saasa +3 more
semanticscholar +1 more source
The depolarizing action of GABA in cultured hippocampal neurons is not due to the absence of ketone bodies. [PDF]
PLoS ONE, 2011 Two recent reports propose that the depolarizing action of GABA in the immature brain is an artifact of in vitro preparations in which glucose is the only energy source. The authors argue that this does not mimic the physiological environment because the
Jaylyn Waddell +3 more
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Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. [PDF]
, 2017 Glutamate is the dominant excitatory neurotransmitter in the brain, but under conditions of metabolic stress it can accumulate to excitotoxic levels.
Andreyev, Alexander Y +12 more
core +1 more source
Circulation: Heart Failure, 2018 Background: Deranged energy metabolism contributes to the pathophysiology of heart failure (HF). Recent studies showed diminished free fatty acid (FFA) oxidation in experimental HF models with a shift towards oxidation of ketone bodies.
G. Voros +7 more
semanticscholar +1 more source
Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention
Nutrients, 2019 An increasing amount of evidence suggests that migraines are a response to a cerebral energy deficiency or oxidative stress levels that exceed antioxidant capacity.
Elena C. Gross +4 more
semanticscholar +1 more source
Detection of Subclinical Ketosis in Dairy Cows [PDF]
Pakistan Veterinary Journal, 2012 Ketosis is a common metabolic disorder frequently observed in dairy cows during the early lactation period. It is characterized by increased levels of ketone bodies in the blood, urine, and milk.
Zhigang Zhang, Guowen Liu1, Hongbin Wang, Xiaobing Li1 and Zhe Wang1*
doaj
Metabolism of ketone bodies in pregnant sheep [PDF]
British Journal of Nutrition, 1982 1. A combination of isotope-dilution and arteriovenous-difference techniques was used to determine the significance of ketones to energy homoeostasis in fasted pregnant ewes.2. There was incomplete interconversion of D(−) 3-hydroxybutyrate (3HB) and acetoacetate (AcAc) and therefore neither entry rate nor oxidation of total ketone bodies could be ...
Pethick, D.W., Lindsay, D.B.
openaire +3 more sources
Effect of dietary fish oil on blood levels of free fatty acids, ketone bodies and triacylglycerol in humans [PDF]
, 1994 Although the reduction of serum triacylglycerol concentrations by dietary fish oil is a well-known effect, the exact mechanism of this effect has not been previously studied in human subjects.
Dagnelie, P.C. (Pieter) +3 more
core +1 more source