Results 51 to 60 of about 23,218 (270)

Thermally Programmable Two‐Port Non‐Hermitian Acoustic Metastructure for Broadband and Direction‐Dependent Absorption

Advanced Science, EarlyView.
A thermally programmable two‐port non‐Hermitian acoustic metastructure is presented, where temperature acts as a non‐geometric tuning variable. Thermal modulation reconfigures impedance matching and loss‐leakage coupling, enabling exceptional‐point driven, broadband, and direction‐dependent sound absorption without requiring geometric reconfiguration ...
Zichao Guo, Zhendong Li, Ziping Lei, Zirui Yang, Kexin Zeng, Zheng Fan, Zhonggang Wang   +6 more
wiley   +1 more source

Pricing Models for a Two-Period Manufacturing and Remanufacturing Process Under Carbon Cap and Trade Mechanism

IEEE Access, 2023
Under carbon cap and trade mechanism, collecting ratio and carbon cap seriously affect the decision of a manufacturer in a closed-loop supply chain. This paper constructs pricing models for manufacturing and remanufacturing products in the presence of ...
Kexin Lou
doaj   +1 more source

Reduced Serum Soluble L-Selectin Levels but Not PCSK9 May Be Associated With Generalized Anxiety Disorder: A Case-Control Study. [PDF]

J Clin Lab Anal
The study included 88 generalized anxiety disorder (GAD) patients and 88 age and sex‐matched healthy controls (HCs). A psychiatrist confirmed the GAD diagnosis, assessed symptom severity using the GAD‐7 scale, and evaluated controls based on the DSM‐5 criteria.
Munny FA, Pranto AH, Paul S, Haque MA, Sharmin R, Sultana S, Hossain MA, Islam MR.   +7 more
europepmc   +2 more sources

Phenotypic homozygous familial hypercholesterolemia successfully treated with proprotein convertase subtilisin/kexin type 9 inhibitors [PDF]

, 2023
Ryosuke Tani, Keiji Matsunaga, yuta toda, Tomoko Inoue, Hai Ying Fu, Tetsuo Minamino   +5 more
openalex   +1 more source

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng, Juping Sun, Junyu Liu, Yuqi Zhang, Wanwan Liu, Xiaobin Li, Han Wu, Juan Li, Jisong Zhang, Chanyuan Jin, Can Yang Zhang   +10 more
wiley   +1 more source

PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice[S]

Journal of Lipid Research, 2015
Proprotein convertase subtilisin kexin type 9 (PCSK9), the last member of the family of Proprotein Convertases related to Subtilisin and Kexin, regulates LDL-cholesterol by promoting the endosomal/lysosomal degradation of the LDL receptor (LDLR). Herein,
Anna Roubtsova, Ann Chamberland, Jadwiga Marcinkiewicz, Rachid Essalmani, Ali Fazel, John J. Bergeron, Nabil G. Seidah, Annik Prat   +7 more
doaj   +1 more source

Machine learning‐based prediction of elevated N terminal pro brain natriuretic peptide among US general population

ESC Heart Failure, Volume 12, Issue 2, Page 859-868, April 2025.
Abstract Aims Natriuretic peptide‐based pre‐heart failure screening has been proposed in recent guidelines. However, an effective strategy to identify screening targets from the general population, more than half of which are at risk for heart failure or pre‐heart failure, has not been well established.
Yuichiro Mori, Shingo Fukuma, Kyohei Yamaji, Atsushi Mizuno, Naoki Kondo, Kosuke Inoue   +5 more
wiley   +1 more source

Expanding the genotypic spectrum of PCSK1 deficiency: A novel mutation in severe neonatal diarrhea

JPGN Reports, EarlyView.
Abstract Among congenital diarrhea and enteropathies (CODEs), proprotein convertase subtilisin/kexin type 1 (PCSK1) deficiency is a rare monogenic disorder, associated with severe neonatal diarrhea and polyendocrinopathies. We report an 18‐day‐old male neonate, born to consanguineous parents, presenting with persistent watery diarrhea, metabolic ...
Eleonora Saraceno, Angelo Corso Faini, Silvia Deaglio, Marianna Pellegrini, Raffaele Buganza, Francesca Giuliani, Pier Luigi Calvo, Michele Pinon   +7 more
wiley   +1 more source

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

Lipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao, Nuan Wang, Di Shi, Hao Zhou, Dan Chen, Guofang Chen   +5 more
wiley   +1 more source

Evaluation of adropin indices and PCSK9 in non-diabetic men with severe obstructive sleep apnea

Türk Biyokimya Dergisi
We aimed to investigate the relationship among proprotein convertase subtilisin/kexin type 9 (PCSK9), adropin levels, inflammation, and sleep variables in non-diabetic males with severe obstructive sleep apnea (OSA).
Deniz Levent, Aral Hale, Akdoğan Özlem, Arslan Hilmi Furkan, Yiğit Enes   +4 more
doaj   +1 more source