Thoracic Cancer, 2019 Background The Ki‐67 labeling index (LI) is a well‐known prognostic factor for primary breast cancer, but its clinical significance for metachronous axillary lymph node (ALN) recurrence has not been well documented.
Naoya Ishibashi +7 more
doaj +1 more source
A cytohistological study of Ki-67 expression in ovarian tumors
Indian Journal of Pathology and Microbiology, 2011 Background and Objective: The study was conducted to evaluate the diagnostic accuracy of imprint cytology in ovarian neoplasms, and to investigate the biological significance of Ki-67 antigen expression in benign and malignant ovarian tumors and ...
Monisha Choudhury +2 more
doaj +1 more source
Ki-67: more than a proliferation marker [PDF]
Chromosoma, 2018 Ki-67 protein has been widely used as a proliferation marker for human tumor cells for decades. In recent studies, multiple molecular functions of this large protein have become better understood. Ki-67 has roles in both interphase and mitotic cells, and its cellular distribution dramatically changes during cell cycle progression.
Xiaoming, Sun, Paul D, Kaufman
openaire +2 more sources
Hypoxia and hyperglycaemia determine why some endometrial tumours fail to respond to metformin [PDF]
, 2020 High expression of Ki67, a proliferation marker, is associated with reduced endometrial cancer-specific survival. Pre-surgical metformin reduces tumour Ki-67 expression in some women with endometrial cancer. Metformin's anti-cancer activity may relate to
Crosbie, EJ +9 more
core +2 more sources
Metallothionein immunoexpression in non-syndromic and syndromic keratocystic odontogenic tumour [PDF]
, 2015 Background: To commpare the metallothionein (MT) immunoexpression in non-syndromic and syndromic keratocystic odontogenic tumour (KOT), to correlate MT with cellular proliferation, and to evaluate the influence of inflammation in MT.
Aguiar, Maria Cássia Ferreira +5 more
core +1 more source
Ki-67 expression in pulmonary tumors [PDF]
Translational Lung Cancer Research, 2016 Ki-67 was introduced more than two decades ago as a measure of the tumor proliferative fraction , in the need for a useful marker that might help clinicians to guide therapy and predict the prognosis of patients with cancer (1). Although several methods have been used to determine the tumor proliferative fraction in the research setting, the only ...
openaire +2 more sources
The cell proliferation antigen Ki-67 organises heterochromatin
eLife, 2016 Antigen Ki-67 is a nuclear protein expressed in proliferating mammalian cells. It is widely used in cancer histopathology but its functions remain unclear. Here, we show that Ki-67 controls heterochromatin organisation.
Michal Sobecki +20 more
doaj +1 more source
Comparison of the value of PCNA and Ki-67 as markers of cell proliferation in ameloblastic tumors [PDF]
, 2012 Objectives: The aim of this study was to compare among PCNAand Ki-67 as the most reliable immunohisto chemical marker for evaluating cell proliferation in ameloblastic tumors.
Bologna-Molina, Ronell +4 more
core +1 more source
The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation. [PDF]
, 2016 Nucleolar protein interacting with the FHA domain of pKi-67 (NIFK) is a Ki-67-interacting protein. However, its precise function in cancer remains largely uninvestigated.
Chang, Hong-Tai +17 more
core +2 more sources
Impact of GLUT1 and Ki-67 expression on early-stage lung adenocarcinoma diagnosed according to a new international multidisciplinary classification [PDF]
, 2013 High expression levels of glucose transporter isoform 1 (GLUT1) and Ki-67 are reportedly associated with malignancy-related clinicopathological factors in malignant tumors. Recently, a new histological IASLC/ATS/ERS classification for lung adenocarcinoma
Asano +55 more
core +1 more source