Results 91 to 100 of about 202,716 (285)

Developing the Quantitative Histopathology Image Ontology : A case study using the hot spot detection problem [PDF]

, 2017
Interoperability across data sets is a key challenge for quantitative histopathological imaging. There is a need for an ontology that can support effective merging of pathological image data with associated clinical and demographic data.
Doyle, Scott, Gurcan, Metin, James, A., John, Overton, N., Tomaszewski, Ruttenberg, Alan, Smith, Barry   +6 more
core  

Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model. [PDF]

, 2016
Inhibitors of BRAFV600E kinase are currently under investigations in preclinical and clinical studies involving BRAFV600E glioma. Studies demonstrated clinical response to such individualized therapy in the majority of patients whereas in some patients ...
Berger, Mitchel S, Daynac, Mathieu, Grossauer, Stefan, James, C David, Koeck, Katharina, McMahon, Martin, Meyers, Ian D, Murphy, Nicole E, Nicolaides, Theodore P, Petritsch, Claudia K, Phillips, Joanna J, Truffaux, Nathalene, Truong, Albert Y   +12 more
core   +1 more source

Carcinoembryonic antigen, α-fetoprotein, and Ki67 as biomarkers and prognostic factors in intrahepatic cholangiocarcinoma: A retrospective cohort study.

Annals of Hepatology, 2020
INTRODUCTION AND OBJECTIVE The purpose of this study was to investigate the expression levels and prognostic roles of α-fetoprotein (AFP), carcinoembryonic antigen (CEA), and Ki67 in tumor tissues of intrahepatic cholangiocarcinoma (ICC) patients ...
Zeyuan Qiang, Wen‐hua Zhang, S. Jin, Kunfu Dai, Yu-ting He, L. Tao, Hailing Yu   +6 more
semanticscholar   +1 more source

Proliferating trichilemmal cyst: The value of ki67 immunostaining

International Journal of Trichology, 2013
A proliferating trichilemmal cyst (PTC) is an uncommon, rapidly-reproducing cutaneous epithelial cyst, differentiating from the isthmic portion of the outer hair root sheath. It is usually described as a benign tumor, but malignant transformation has been reported and is then denominated as a malignant proliferating trichilemmal tumor.
Rangel-Gamboa, Lucia, Reyes-Castro, Magdalena, Dominguez-Cherit, Judith, Vega-Memije, Elisa   +3 more
openaire   +3 more sources

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma. [PDF]

, 2015
Medulloblastoma (MB) is a highly malignant brain tumor that occurs primarily in children. Although surgery, radiation and high-dose chemotherapy have led to increased survival, many MB patients still die from their disease, and patients who survive ...
Berezov, A, Brun, SN, Conway, EM, Crawford, JR, Esparza, LA, Garcia, G, Grant, GA, Greene, MI, Huang, J-M, Levy, ML, Li, X-N, Markant, SL, Nakano, I, Pavlyukov, MS, Smith, LH, Terry, D, Wang, Q, Wechsler-Reya, RJ   +17 more
core   +2 more sources

p53, ER, and Ki67 Expression in Canine Mammary Carcinomas and Correlation With Pathological Variables and Prognosis

Veterinary Pathology-Supplement, 2020
Using immunohistochemistry, 170 canine mammary carcinomas were evaluated for p53, ER (estrogen receptor), and Ki67. Of the 170 tumors, 89 were grade I (52.3%), 36 were grade II (21.2%), and 45 were grade III (26.4%).
B. Brunetti, B. Bacci, C. Angeli, C. Benazzi, L. V. Muscatello   +4 more
semanticscholar   +1 more source

A comparative study between Ki67 positive versus Ki67 negative females with breast cancer: Cross sectional study

Annals of Medicine and Surgery, 2020
The prognosis of breast cancer depends on several clinical and pathological parameters most importantly the clinical stage, other factors predicting the outcome are hormone receptors like estrogen and progesterone receptors. Expression of Ki67 also have been shown to affect the outcome.This retrospective study included 278 female patients diagnosed and
openaire   +2 more sources

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. [PDF]

, 2020
Copper levels are known to be elevated in inflamed and malignant tissues. But the mechanism underlying this selective enrichment has been elusive. In this study, we report a axis by which inflammatory cytokines, such as IL-17, drive cellular copper ...
Bao, Shideng, Bulek, Katarzyna, Cai, Gang, Chang, Christopher J, Chen, Xing, Fox, Paul L, Huang, Emina, Jackson, Mark W, Jia, Shang, Kalady, Matthew F, Li, Xiaoxia, Liao, Yun, Pizarro, Theresa T, Sen, Ganes C, Stark, George R, Tang, Fangqiang, Zhao, Junjie   +16 more
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