Results 21 to 30 of about 202,716 (285)

Synaptophysin-Ki67 double stain: a novel technique that improves interobserver agreement in the grading of well-differentiated gastrointestinal neuroendocrine tumors. [PDF]

, 2017
A common problem in the assessment of Ki67 proliferative index in well-differentiated gastrointestinal neuroendocrine tumors is distinguishing tumor from non-tumor.
Beckett, Laurel, Gandour-Edwards, Regina, Gui, Dorina, Li, Yueju, Matsukuma, Karen, Olson, Kristin A   +5 more
core   +1 more source

Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer

Journal of the National Cancer Institute, 2009
Background Gene expression profiling of breast cancer has identified two biologically distinct estrogen receptor (ER)-positive subtypes of breast cancer: luminal A and luminal B.
M. Cheang, S. Chia, D. Voduc, D. Gao, S. Leung, J. Snider, M. Watson, S. Davies, P. Bernard, J. Parker, C. Perou, M. Ellis, T. Nielsen   +12 more
semanticscholar   +1 more source

Ki67 Labelling Index predicts clinical outcome and survival in oral squamous cell carcinoma

Journal of Applied Oral Science, 2021
Objective To investigate the Ki 67 expression and its correlation with clinicopathological features and 3 years as well as 5 years survival rate in oral squamous cell carcinoma (OSCC).
A. Gadbail, S. Sarode, M. Chaudhary, S. Gondivkar, S. Tekade, M. Yuwanati, S. Patil   +6 more
semanticscholar   +1 more source

HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis [PDF]

, 2009
Penile verrucous carcinoma is a rare disease and little is known of its aetiology or pathogenesis. In this study we examined cell-cycle proteins expression and correlation with human papillomavirus infection in a series of 15 pure penile verrucous ...
A Ouban, AL Cubilla, AL Cubilla, AL Cubilla, AL Cubilla, AL Cubilla, AL Seixas, AS Masih, AS Narayana, B Kleter, C Dianzani, C Missero, Catherine Corbishley, CB Bunker, CL Haycox, Daniel M Berney, David M Prowse, DE Johnson, DM Prowse, E Ferreux, EF Velazquez, Elena Ktori, Elzbieta Stankiewicz, FT Kraus, GD Higgins, IB Roninson, Jack Cuzick, JC Noel, JR Nevins, KH Cuesta, KW Chan, KY Lam, KY Lam, L Gregoire, Laurence Ambroisine, LC Cubilla, LH Sobin, LL Villa, LV Ackerman, M Gualco, M Senba, M Serrano, M Wong, MA Rubin, MR Cupp, MT Kiyabu, Nicholas Watkin, PA Adegboyega, PA Hall, PH McKee, S Pilotti, Sakunthala C Kudahetti, SL Harris, T Sano, TH Cheung, VA Tron, VA Varma, Xiaoxi Zhang, Y Koyamatsu   +58 more
core   +1 more source

Ki67 is a Graded Rather than a Binary Marker of Proliferation versus Quiescence.

Cell Reports, 2018
Ki67 staining is widely used as a proliferation indicator in the clinic, despite poor understanding of this protein's function or dynamics. Here, we track Ki67 levels under endogenous control in single cells over time and find that Ki67 accumulation ...
Iain Miller, Mingwei Min, Chen Yang, Chengzhe Tian, Sara E. Gookin, Dylan Carter, S. Spencer   +6 more
semanticscholar   +1 more source

Dynamic changes in connexin expression correlate with key events in the wound healing process. [PDF]

, 2003
Wound healing is a complex process requiring communication for the precise co-ordination of different cell types. The role of extracellular communication through growth factors in the wound healing process has been extensively documented, but the role of
Becker, David L, Coutinho, Petula, Frank, Stefanie, Qiu, Cindy, Tamber, Kamaldeep   +4 more
core   +1 more source

Repurposing metformin for cancer treatment: current clinical studies. [PDF]

, 2016
In recent years, several studies have presented evidence suggesting a potential role for metformin in anti-cancer therapy. Preclinical studies have demonstrated several anticancer molecular mechanisms of metformin including mTOR inhibition, cytotoxic ...
Altman, Jessica K, Arya, Ayush, Carneiro, Benedito, Chae, Young Kwang, Chandra, Sunandana, Giles, Francis, Kalyan, Aparna, Kaplan, Jason, Malecek, Mary-Kate, Platanias, Leonidas, Shin, Daniel Sanghoon   +10 more
core   +1 more source

Low correlation between Ki67 assessed by qRT-PCR in Oncotype Dx score and Ki67 assessed by Immunohistochemistry [PDF]

Scientific Reports, 2022
AbstractBreast cancers expressing high levels of Ki67 are associated with poor outcomes. Oncotype DX test was designed for ER+/HER2− early-stage breast cancers to help adjuvant chemotherapy decision by providing a Recurrent Score (RS). RS measures the expression of 21 specific genes from tumor tissue, including Ki67.
Selmani, Zohair, Molimard, Chloé, Overs, Alexis, Bazan, Fernando, Chaigneau, Loic, Dobi, Erion, Meneveau, Nathalie, Mansi, Laura, Paillard, Marie-Justine, Meynard, Guillaume, Viot, Julien, Algros, Marie-Paule, Borg, Christophe, Feugeas, Jean-Paul, Pivot, Xavier, Prétet, Jean-Luc, Curtit, Elsa   +16 more
openaire   +5 more sources

Tumor-reactive immune cells protect against metastatic tumor and induce immunoediting of indolent but not quiescent tumor cells [PDF]

, 2016
Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppressor cells and poor immunogenicity of the tumor-expressing self-antigens.
Bear, Harry D., Graham, Laura, Idowu, Michael O., Keim, Rebecca, Manjili, Masoud H., Payne, Kyle K., Toor, Amir A., Wan, Wen, Wang, Xiang-Yang   +8 more
core   +2 more sources

Correlationship between Ki67, VEGF, and p53 and Hepatocellular Carcinoma Recurrence in Liver Transplant Patients

BioMed Research International, 2021
Background and Aims Patients with hepatocellular carcinoma (HCC) who undergo orthotopic liver transplantation (OLT) are at risk for posttransplant tumor recurrence.
Xia Zhang, Zhixian Wu, Yonghai Peng, Dongliang Li, Yi Jiang, Fan Pan, Yi Li, Yanhua Lai, Z. Cui, Kun Zhang   +9 more
semanticscholar   +1 more source