Results 21 to 30 of about 203,911 (336)

Siah2 control of T-regulatory cells limits anti-tumor immunity. [PDF]

, 2020
Understanding the mechanisms underlying anti-tumor immunity is pivotal for improving immune-based cancer therapies. Here, we report that growth of BRAF-mutant melanoma cells is inhibited, up to complete rejection, in Siah2-/- mice.
Aifantis, Ioannis, Bosenberg, Marcus, Bradley, Linda M, Brown, Kevin, Dolgalev, Igor, Feng, Yongmei, Hockemeyer, Kathryn, Li, Yan, Marine, Jean-Christophe, Otero, Dennis C, Poźniak, Joanna, Rambow, Florian, Ronai, Ze'ev A, Scortegagna, Marzia, Tinoco, Roberto, Zhang, Tongwu   +15 more
core   +2 more sources

Ki67 assessment in invasive luminal breast cancer: a comparative study between different scoring methods

Histopathology, 2022
Ki67 reflects the proliferation activity in breast cancer (BC). However, an optimal method for its assessment in clinical settings has yet to be robustly defined.
Ayat G. Lashen, M. Toss, A. Green, N. Mongan, E. Rakha   +4 more
semanticscholar   +1 more source

Ki67 for evaluating the prognosis of gastrointestinal stromal tumors: A systematic review and meta-analysis

Oncology Letters, 2022
Overexpression of Ki67 is observed in tumor cells, and it has been suggested to be a marker for cancer prognosis. However, the relationship between Ki67 expression and the risk of recurrence of gastrointestinal stromal tumors (GISTs) remains poorly ...
Ji Li, Anzhe Wang, Xiao-dong Chen, H. Pan, Shi-Qiang Li   +4 more
semanticscholar   +1 more source

Long-term outcome and prognostic value of Ki67 after perioperative endocrine therapy in postmenopausal women with hormone-sensitive early breast cancer (POETIC): an open-label, multicentre, parallel-group, randomised, phase 3 trial

The Lancet Oncology, 2020
Summary Background Preoperative and perioperative aromatase inhibitor (POAI) therapy has the potential to improve outcomes in women with operable oestrogen receptor-positive primary breast cancer.
I. Smith, J. Robertson, L. Kilburn, M. Wilcox, A. Evans, C. Holcombe, K. Horgan, C. Kirwan, E. Mallon, M. Sibbering, A. Skene, R. Vidya, M. Cheang, J. Banerji, J. Morden, Kally Sidhu, A. Dodson, J. Bliss, M. Dowsett   +18 more
semanticscholar   +1 more source

Noninvasive Method for Predicting the Expression of Ki67 and Prognosis in Non-Small-Cell Lung Cancer Patients: Radiomics

Journal of Healthcare Engineering, 2022
Purpose In this study, we aimed to develop and validate a noninvasive method based on radiomics to evaluate the expression of Ki67 and prognosis of patients with non-small-cell lung cancer (NSCLC). Patients and Methods. A total of 120 patients with NSCLC
W. Yao, Yifeng Liao, Xiapeng Li, Feng Zhang, Haifeng Zhang, Baoli Hu, Xiaolong Wang, Li Li, Mei Xiao   +8 more
semanticscholar   +1 more source

Effects of neoadjuvant trastuzumab, pertuzumab and palbociclib on Ki67 in HER2 and ER-positive breast cancer

npj Breast Cancer, 2022
The crosstalk between estrogen and HER2 receptors and cell-cycle regulation sustains resistance to endocrine therapy of HER2- and hormone receptor-positive breast cancer.
L. Gianni, M. Colleoni, G. Bisagni, M. Mansutti, C. Zamagni, L. Del Mastro, S. Zambelli, G. Bianchini, A. Frassoldati, I. Maffeis, P. Valagussa, G. Viale   +11 more
semanticscholar   +1 more source

Differential challenges in salivary gland neoplasms [PDF]

Archives of Biological Sciences, 2021
Salivary gland tumors are neoplasms characterized by a high level of pleomorphism and histological overlap. One tumor may contain several cell types; therefore, it is necessary to include immunohistochemical staining, as well as morphometric analysis of ...
Živković Nikola, Kostić Miloš, Cvetanović Ana, Jovičić-Milentijević Maja, Spasić Milan, Petrović Milica, Trajković Miloš, Denčić Tijana, Krtinić Dane   +8 more
doaj   +1 more source

Synaptophysin-Ki67 double stain: a novel technique that improves interobserver agreement in the grading of well-differentiated gastrointestinal neuroendocrine tumors. [PDF]

, 2017
A common problem in the assessment of Ki67 proliferative index in well-differentiated gastrointestinal neuroendocrine tumors is distinguishing tumor from non-tumor.
Beckett, Laurel, Gandour-Edwards, Regina, Gui, Dorina, Li, Yueju, Matsukuma, Karen, Olson, Kristin A   +5 more
core   +1 more source

Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer

Journal of the National Cancer Institute, 2009
Background Gene expression profiling of breast cancer has identified two biologically distinct estrogen receptor (ER)-positive subtypes of breast cancer: luminal A and luminal B.
M. Cheang, S. Chia, D. Voduc, D. Gao, S. Leung, J. Snider, M. Watson, S. Davies, P. Bernard, J. Parker, C. Perou, M. Ellis, T. Nielsen   +12 more
semanticscholar   +1 more source

Ki67 Labelling Index predicts clinical outcome and survival in oral squamous cell carcinoma

Journal of Applied Oral Science, 2021
Objective To investigate the Ki 67 expression and its correlation with clinicopathological features and 3 years as well as 5 years survival rate in oral squamous cell carcinoma (OSCC).
A. Gadbail, S. Sarode, M. Chaudhary, S. Gondivkar, S. Tekade, M. Yuwanati, S. Patil   +6 more
semanticscholar   +1 more source