Results 61 to 70 of about 1,061,703 (360)

Signaling pathways of chronic kidney diseases, implications for therapeutics

open access: yesSignal Transduction and Targeted Therapy, 2022
Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) deposition.
Q. Yuan, B. Tang, Chun Zhang
semanticscholar   +1 more source

Hyperglycemia and Hyperlipidemia Act Synergistically to Induce Renal Disease in LDL Receptor-Deficient BALB Mice [PDF]

open access: yes, 2004
Diabetic nephropathy is the leading cause of end-stage renal disease in Western countries, but only a portion of diabetic patients develop diabetic nephropathy.
Alpers, Charles E.   +6 more
core   +1 more source

Alcian blue as a kidney staining in diabetic mice

open access: yesJurnal Teknologi Laboratorium, 2022
One of the complications of Diabetes Mellitus (DM) is damage to the kidneys. Using L. plantarum, it can reduce glucose levels so that it is also possible to repair damaged kidney structures.
Sri Sinto Dewi   +3 more
doaj   +1 more source

The role of zinc in renal pathological changes in diabetic status [PDF]

open access: yes, 2015
Diabetes mellitus (DM) was the 8th leading cause of death in 2011, resulting in 1.4 million deaths worldwide. One of the complications of DM is chronic kidney disease, which accounts for nearly 44% of all new cases of kidney failure in the US in 2011 ...
Fernando, Julie, Zhou, Shaobo
core   +1 more source

Non-Albumin Proteinuria (NAP) as a Complementary Marker for Diabetic Kidney Disease (DKD)

open access: yesLife, 2021
Diabetic kidney disease (DKD) is one of the most common forms of chronic kidney disease. Its pathogenic mechanism is complex, and it can affect entire structures of the kidney.
Jaehyun Bae   +2 more
doaj   +1 more source

Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]

open access: yes, 2014
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad   +6 more
core   +2 more sources

Somatostatin-like immunoreactivity in the glomerulus of rat kidney

open access: yesKidney International, 1983
It has been shown that somatostatin inhibits the antidiuretic action of vasopressin in toad urinary bladder in vitro and in dogs and rats in vivo. The presence of somatostatin-like immunoreactivity (SLI) in the urinary bladder and kidney of the toad has suggested the possibility that somatostatin may act as a local paracrine hormone modulating the ...
Kurokawa, Kiyoshi   +3 more
openaire   +2 more sources

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

MLP-UNet: Glomerulus Segmentation

open access: yesIEEE Access, 2023
Glomerulus segmentation in kidney tissue segments is a crucial nephropathology process used to diagnose renal diseases effectively. This study proposes a novel and robust application of MLP (Multi-Layer Perceptron) based architectures for the ...
Franchis N Saikia   +5 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

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