Results 11 to 20 of about 45,578 (261)

mutation: a benign genetic cause of proteinuria? [PDF]

open access: yesChildhood Kidney Diseases, 2023
Proteinuria is an important risk factor for renal and cardiovascular disease. It is associated with a risk for glomerulonephritis, chronic kidney disease, and end-stage renal disease.
Hyun Kyung Lee
doaj   +1 more source

Iron Is Filtered by the Kidney and Is Reabsorbed by the Proximal Tubule [PDF]

open access: yesFrontiers in Physiology, 2021
The aim of this study was to determine the iron (Fe) concentration profile within the lumen of the S2 renal proximal convoluted tubule (PCT) and to resolve whether this nephron segment transported Fe. To do this, we performed in vivo renal micropuncture on Wistar rats, collected PCT tubular fluid from superficial nephrons, and measured Fe concentration.
Wareing, Mark, Smith, Craig P.
openaire   +3 more sources

Morphological description and histological structure of the Hedgehog Kidney (Hemiechinus auritus)

open access: yesTikrit Journal of Pure Science, 2023
This study was aimed to recognize the morphological description and histological structure of the kidney in hedgehog (Hemiechinus auritus). The morphological results showed that the kidney has a small bean shape and reddish brown color.
Thekra Atta   +4 more
doaj   +1 more source

Expression of Bcl-2 and Bax in mouse renal tubules during kidney development. [PDF]

open access: yesPLoS ONE, 2012
Bcl-2 and Bax play an important role in apoptosis regulation, as well as in cell adhesion and migration during kidney morphogenesis, which is structurally and functionally related to mitochondria.
Xiao-Feng Song   +4 more
doaj   +1 more source

Stx2 Induces Differential Gene Expression and Disturbs Circadian Rhythm Genes in the Proximal Tubule

open access: yesToxins, 2022
Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown.
Fumiko Obata   +4 more
doaj   +1 more source

Bioengineered Cystinotic Kidney Tubules Recapitulate a Nephropathic Phenotype

open access: yesCells, 2022
Nephropathic cystinosis is a rare and severe disease caused by disruptions in the CTNS gene. Cystinosis is characterized by lysosomal cystine accumulation, vesicle trafficking impairment, oxidative stress, and apoptosis. Additionally, cystinotic patients
Elena Sendino Garví   +2 more
doaj   +1 more source

Fine Structure of the Trunk Kidney and Distribution of Its Secreted Exosomes in the Adult Zebrafish

open access: yesShiyan dongwu yu bijiao yixue, 2023
Objective To observe the fine structure of the trunk kidney in zebrafish, and to identify its secreted exosomes.Methods The microstructure and ultrastructure of the trunk kidney in zebrafish were observed by light microscopy and electron microscopy, and ...
LIN Jinxing   +5 more
doaj   +1 more source

Mechanosensory function of microvilli of the kidney proximal tubule [PDF]

open access: yesProceedings of the National Academy of Sciences, 2004
Normal variations in glomerular filtration induce proportional changes in proximal tubule Na + reabsorption. This “glomerulotubular balance” derives from flow dependence of Na + uptake across luminal cell membranes; however, the underlying physical ...
Zhaopeng, Du   +5 more
openaire   +2 more sources

Visualization of Calcium Dynamics in Kidney Proximal Tubules [PDF]

open access: yesJournal of the American Society of Nephrology, 2015
Intrarenal changes in cytoplasmic calcium levels have a key role in determining pathologic and pharmacologic responses in major kidney diseases. However, cell-specific delivery of calcium-sensitive probes in vivo remains problematic. We generated a transgenic rat stably expressing the green fluorescent protein-calmodulin-based genetically encoded ...
Szebényi, Kornélia   +13 more
openaire   +3 more sources

The kidney of the Nodularia freshwater mussel has a larger filtration-size and counter-current system with improved water excretion compared with the seawater mussel Mytilus

open access: yesBiology Open, 2021
Histological studies and magnetic resonance imaging were employed to analyze the kidney structure and function of the freshwater mussel, Nodularia douglasiae. The Nodularia kidney consists of proximal, intermediate and distal tubules.
Eriko Seo   +2 more
doaj   +1 more source

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