Cell volume regulation in the proximal tubule of rat kidney proximal tubule cell volume regulation [PDF]
, 2017 We developed a dynamic model of a rat proximal convoluted tubule cell in order to investigate cell volume regulation mechanisms in this nephron segment.
Edwards, Aurelie, Layton, Anita T.
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Immunohistochemical localization of catalase in geese (anser anser) kidney [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 The aim of this study is to observe the histologic structure of kidney tissue of geese and to determine the immunohistochemical localization of catalase in it. Six female geese were used in our study.
Serap KORAL TAŞÇI +4 more
doaj +1 more source
Endothelin-1 Drives Epithelial-Mesenchymal Transition In Hypertensive Nephroangiosclerosis [PDF]
, 2016 BACKGROUND: Tubulointerstitial fibrosis, the final outcome of most kidney diseases, involves activation of epithelial mesenchymal transition (EMT). Endothelin‐1 (ET‐1) activates EMT in cancer cells, but it is not known whether it drives EMT in the kidney.
Belloni, Anna S +13 more
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miR-127 protects proximal tubule cells against ischemia/reperfusion : identification of Kinesin family member 3B as miR-127 target [PDF]
, 2012 Ischemia/reperfusion (I/R) is at the basis of renal transplantation and acute kidney injury. Molecular mechanisms underlying proximal tubule response to I/R will allow the identification of new therapeutic targets for both clinical settings.
Aguado-Fraile, Elia +9 more
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Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules
AAPS Journal, 2018 Proximal tubules in the kidney play a crucial role in reabsorbing and eliminating substrates from the body into the urine, leading to high local concentrations of xenobiotics.
M. Vormann +17 more
semanticscholar +1 more source
Histological Characteristics of the Kidney in Mongolian Gerbils of Different Ages
Shiyan dongwu yu bijiao yixue, 2023 ObjectiveTo explore the histological characteristics of the kidney in Mongolian gerbils of different ages.MethodsTen Mongolian gerbils of 2, 6, and 12 months old (half male and half female) were selected.
LU Lingqun +4 more
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MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury [PDF]
, 2016 Murine double minute-2 (MDM2) is an E3-ubiquitin ligase and the main negative regulator of tumor suppressor gene p53. MDM2 has also a non-redundant function as a modulator of NF-kB signaling. As such it promotes proliferation and inflammation.
Anders, Hans-Joachim +10 more
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Kidney regeneration: common themes from the embryo to the adult [PDF]
, 2013 The vertebrate kidney has an inherent ability to regenerate following acute damage. Successful regeneration of the injured kidney requires the rapid replacement of damaged tubular epithelial cells and reconstitution of normal tubular function ...
Cirio, Maria Cecilia +4 more
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Scientific Reports, 2018 Fibroblast growth factor 23 (FGF23) plays critical roles in phosphate handling and vitamin D metabolism in the kidney. However, the effector cells of FGF23 in the kidney remain unclear.
Ai Takeshita +4 more
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Changes in renal WT-1 expression preceding hypertension development [PDF]
, 2016 Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica +8 more
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