Results 21 to 30 of about 45,578 (261)

Proximal Tubule p53 in Cold Storage/Transplantation-Associated Kidney Injury and Renal Graft Dysfunction

open access: yesFrontiers in Medicine, 2021
Kidney injury associated with cold storage/transplantation is a primary factor for delayed graft function and poor outcome of renal transplants. p53 contributes to both ischemic and nephrotoxic kidney injury, but its involvement in kidney cold storage ...
Xiaohong Xiang   +8 more
doaj   +1 more source

Light chain proximal tubulopathy with lambda restriction presenting as acute kidney injury [PDF]

open access: yesJournal of Nephropathology, 2021
Monoclonal gammopathies can produce a variety of glomerular, tubular, vascular and interstitial lesions. The spectrums of renal lesions produced by these monoclonal gammopathies include AL/AH amyloidosis, light chain cast nephropathy or myeloma kidney ...
Asha Thomas   +4 more
doaj   +1 more source

Immunohistochemical localization of catalase in geese (anser anser) kidney [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2019
The aim of this study is to observe the histologic structure of kidney tissue of geese and to determine the immunohistochemical localization of catalase in it. Six female geese were used in our study.
Serap KORAL TAŞÇI   +4 more
doaj   +1 more source

Cell Volume Regulation in the Proximal Tubule of Rat Kidney [PDF]

open access: yesBulletin of Mathematical Biology, 2017
We developed a dynamic model of a rat proximal convoluted tubule cell in order to investigate cell volume regulation mechanisms in this nephron segment. We examined whether regulatory volume decrease (RVD), which follows exposure to a hyposmotic peritubular solution, can be achieved solely via stimulation of basolateral K[Formula: see text] and ...
Aurélie Edwards, Anita T. Layton
openaire   +3 more sources

Histological Characteristics of the Kidney in Mongolian Gerbils of Different Ages

open access: yesShiyan dongwu yu bijiao yixue, 2023
ObjectiveTo explore the histological characteristics of the kidney in Mongolian gerbils of different ages.MethodsTen Mongolian gerbils of 2, 6, and 12 months old (half male and half female) were selected.
LU Lingqun   +4 more
doaj   +1 more source

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism

open access: yesScientific Reports, 2018
Fibroblast growth factor 23 (FGF23) plays critical roles in phosphate handling and vitamin D metabolism in the kidney. However, the effector cells of FGF23 in the kidney remain unclear.
Ai Takeshita   +4 more
doaj   +1 more source

Histological, Ultrastructural, and Biochemical Study of the Reno-Protective Effects of Uncaria Tomentosa and L-arginine Against Fipronil-Induced Nephrotoxicity in Male Albino Rats [PDF]

open access: yesThe Egyptian Journal of Histology, 2023
Introduction: Fipronil induces vulnerable effects on the kidney causing nephrotoxicity via oxidative stress. The purpose of this study was to compare the protective effects of Uncaria tomentosa versus L-arginine against fipronil induced nephrotoxicity ...
Nema Soliman   +3 more
doaj   +1 more source

Sex-Specific Computational Models of Kidney Function in Patients With Diabetes

open access: yesFrontiers in Physiology, 2022
The kidney plays an essential role in homeostasis, accomplished through the regulation of pH, electrolytes and fluids, by the building blocks of the kidney, the nephrons.
Sangita Swapnasrita   +3 more
doaj   +1 more source

Intratubular, Intracellular, and Mitochondrial Angiotensin II/AT1 (AT1a) Receptor/NHE3 Signaling Plays a Critical Role in Angiotensin II-Induced Hypertension and Kidney Injury

open access: yesFrontiers in Physiology, 2021
Hypertension is well recognized to be the most important risk factor for cardiovascular diseases, stroke, and end-stage kidney failure. A quarter of the world’s adult populations and 46% of the US adults develop hypertension and currently require ...
Xiao Chun Li   +3 more
doaj   +1 more source

The proximal tubule in the pathophysiology of the diabetic kidney

open access: yesAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2011
Diabetic nephropathy is a leading cause of end-stage renal disease. A better understanding of the molecular mechanism involved in the early changes of the diabetic kidney may permit the development of new strategies to prevent diabetic nephropathy. This review focuses on the proximal tubule in the early diabetic kidney, particularly on its exposure and
openaire   +3 more sources

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