Results 211 to 220 of about 45,578 (261)

Targeting YAP1‐Mediated Tubular Cell Senescence to Attenuate Maladaptive Repair and Fibrotic Transition After Acute Kidney Injury

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
YAP1 mediates tubular cell senescence and drives maladaptive repair following AKI, promoting the AKI to CKD transition. Single‐cell RNA‐seq reveals sustained YAP1 overexpression, fibroblast activation, and pro‐fibrotic tubular cell shift. Senolytic agents or verteporfin (YAP1/TEAD1 inhibitor) suppress YAP1 activity, reduce renal senescence, alleviate ...
Zhibo Zhao, Huiping An, Yonghou Sang, Si Chen, Jinxiu Zhou, Tingting Zhang, Junhu Li, Xiaoshuang Zhou   +7 more
wiley   +1 more source

From glucosuria to dialysis: a case report of osmotic nephropathy due to an SGLT2 inhibitor. [PDF]

BMC Nephrol
Castellanos-de la Hoz J, Molano-Triviño A, González-García YF, Espinosa Saltaren LM, Zúñiga-Rodríguez E.   +4 more
europepmc   +1 more source

Renal tubular lysozyme in tubulointerstitial diseases and renal sarcoidosis. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Sanada S, Sato M.
europepmc   +1 more source

Co-induction of stromal and epithelial progenitors for renal regeneration. [PDF]

Innovation (Camb)
Vincent T, Nademi S, Namestnikov M, Cohen-Zontag O, Dekel B, Freedman BS.   +5 more
europepmc   +1 more source

The effects of elevated phosphate on the kidney - damaging the gatekeeper. [PDF]

Pflugers Arch
Mitchell T, Verma V, Fajol A, Faul C.
europepmc   +1 more source

Modulation of PKCα/ETS1 by klotho restores CYB5R4-dependent mitochondrial function in proximal tubular epithelial cells to attenuate the progression of diabetic kidney disease. [PDF]

Cardiovasc Diabetol
Gan C, Zhou X, Qiu L, Chen D, Shi Y, Yang Q, Jiang H, Xiao H, Chen W, Yang X, Chen Y, Wang M, Yang H, Jiang W, Li Q.   +14 more
europepmc   +1 more source

Osmotic nephropathy as a potentially underrecognized cause of acute kidney injury during SGLT2 inhibitor therapy: a case report and literature review. [PDF]

CEN Case Rep
Murata A, Tanaka M, Takayoshi M, Matsuyama Y, Sato R, Ishida Y, Teragaki M, Iwanari S, Ikeda M, Takeoka H.   +9 more
europepmc   +1 more source

THE BASE OF THE PROXIMAL CONVOLUTED TUBULE CELLS OF RAT KIDNEY [PDF]

Journal of Cell Biology, 1957
The three dimensional arrangement of the compartments on the base of proximal convoluted tubule cells of rat kidney is described. An extracellular basal labyrinth is found to be enclosed by these compartments. The compartments with their mitochondria and the basal labyrinth are regarded as forming a functional unit.
H Ruska, Moore Dan H, Ruska Helmut
exaly   +3 more sources

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Lipids in the Proximal Tubules of the Kidney in Diabetic Coma

The American Journal of Forensic Medicine and Pathology, 2000
Vacuolization of the renal tubular epithelial cells (the Armanni-Ebstein lesion) associated with diabetic hyperglycemia is usually regarded as an accumulation of glycogen. In a case of death of diabetic coma, the vacuoles were stained strongly for lipids.
Thomsen, J.L., Hansen, T.P.
openaire   +2 more sources

Secretion of tetraethylammonium by proximal tubules of rabbit kidneys

American Journal of Physiology-Renal Physiology, 1983
The secretory transport of tetraethylammonium (TEA) was investigated in perfused and nonperfused isolated S1, S2, and S3 segments of proximal tubules from rabbit kidneys. In the perfused tubules the transepithelial net secretory flux and in nonperfused tubules the TEA cellular uptake were saturable (Km = 67 microM, Vmax = 2,480 fmol X min-1 X mm-1 in ...
C, Schäli, L, Schild, J, Overney, F, Roch-Ramel   +3 more
openaire   +2 more sources