Results 221 to 230 of about 73,145 (294)

Advanced Glycation End Products Mediate Epigenetic Alteration of H3K27me3 in Renal Proximal Tubular Cells: Potential Role in Metabolic Memory. [PDF]

Cells
Ludewig L, Bondeva T, Liebisch M, Ihle J, Loeffler I, Wolf G.   +5 more
europepmc   +1 more source

Kidney disease impairs tendon function in rats

The Journal of Physiology, Volume 604, Issue 3, Page 1113-1136, 1 February 2026.
Abstract figure legend This study demonstrates for the first time that tendon strength is reduced in a rodent model of chronic kidney disease (8 weeks of 0.25% adenine feeding) and confirms concurrent dysfunction in muscle and bone. These findings provide novel characterization of multiple tissues, paving the way for future investigations into the ...
Christopher M. T. Hayden, Natalie K. Gilmore, Benjamin Osipov, Sarah E. Brashear, Marc Gorge, Juang‐Yu Jen, Lucas R. Smith, Blaine A. Christiansen, Baback Roshanravan, Keith Baar   +9 more
wiley   +1 more source

Histopathological Scoring of Renal Injury in an Experimental Model of Acute Pancreatitis Caused by <i>Karwinskia humboldtiana</i> Fruit: Exploring Its Potential Utility in the Treatment of Pancreatic Cancer. [PDF]

Pharmaceuticals (Basel)
Esparza-Rodríguez N, Solís-Flores NJ, Medellín-Zapata GG, Segoviano-Ramírez JC, Carcaño-Díaz K, Ortega-Martínez M, Jaramillo-Rangel G, García-Juárez J.   +7 more
europepmc   +1 more source

Hypertension and age‐related focal global glomerulosclerosis are associated with biomarkers for cellular senescence

Physiological Reports, Volume 14, Issue 3, February 2026.
Abstract Arterionephrosclerosis is characterized by focal global glomerulosclerosis (FGGS), which is a constant feature of aging and hypertension. FGGS begins as normal‐appearing glomeruli that undergo tuft contraction (TC) and progress to global glomerulosclerosis (GGS).
Michael D. Hughson, Alaa A. Ali, Yusuke Okabayashi, Victor G. Puelles, John F. Bertram   +4 more
wiley   +1 more source

Proximal Tubule‐Specific Genetic Deficiency of PPARα Worsens Systemic Lipid and Glucose Metabolism During Fasting

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Proximal tubule‐specific PPARα knockout mouse (PPARαΔKPT) showed decreased lipid and glucose metabolism in the kidney during fasting. Metabolism in the other organs was increased, presumably as a means of compensating for the impaired kidney metabolism.
Daiki Aomura, Takayuki Nimura, Kosuke Yamaka, Yosuke Yamada, Makoto Harada, Takero Nakajima, Takefumi Kimura, Koji Hashimoto, Hiroyuki Kanno, Motoko Yanagita, Frank J. Gonzalez, Naoki Tanaka, Yuji Kamijo   +12 more
wiley   +1 more source

Ultrastructural and Immunohistochemical Study on the Nephrotoxicity Following Intravitreal Administration of the Antifungal Agents Voriconazole and Micafungin in New Zealand White Rabbits. [PDF]

Int J Mol Sci
Karachrysafi S, Karakousis VA, Liatsos A, Kavvadas D, Ioannou D, Anastasiadou P, Kofidou E, Karampatakis V, Sioga A, Raikos N, Papamitsou T.   +10 more
europepmc   +1 more source

Using spatial proteomics to enhance cell type assignments in histology images. [PDF]

Cell Rep Methods
Dayao MT, Mayer AT, Trevino AE, Bar-Joseph Z.   +3 more
europepmc   +1 more source

Cage-Farming Causes Histopathological Alterations in the Renal Tissues of the Rainbow Trout <i>Oncorhynchus mykiss</i> (Walbaum, 1792). [PDF]

Int J Mol Sci
Ugrin M, Fernandez Godoy M, Restović I, Hrabar J, Kević N, Bočina I.   +5 more
europepmc   +1 more source

AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids. [PDF]

Signal Transduct Target Ther
Gupta N, Zhang K, Sabbisetti V, Shu J, Morizane R.   +4 more
europepmc   +1 more source