Light chain proximal tubulopathy with lambda restriction presenting as acute kidney injury [PDF]
Journal of Nephropathology, 2021 Monoclonal gammopathies can produce a variety of glomerular, tubular, vascular and interstitial lesions. The spectrums of renal lesions produced by these monoclonal gammopathies include AL/AH amyloidosis, light chain cast nephropathy or myeloma kidney ...
Asha Thomas +4 more
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Immunohistochemical localization of catalase in geese (anser anser) kidney [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 The aim of this study is to observe the histologic structure of kidney tissue of geese and to determine the immunohistochemical localization of catalase in it. Six female geese were used in our study.
Serap KORAL TAŞÇI +4 more
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Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]
, 2014 Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Dunn, Kadeshia +3 more
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Fructose Acutely Stimulates NHE3 Activity in Kidney Proximal Tubule [PDF]
Kidney and Blood Pressure Research, 2012 Fructose causes a sodium-sensitive hypertension and acutely reduces the urinary Na+ excretion, suggesting that it may regulate the activity of renal tubular sodium transporters. NHE3 is highly expressed in proximal tubule (PT), along with proteins that mediate fructose transport and metabolism.
Gabriella D, Queiroz-Leite +6 more
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Mechanosensory function of microvilli of the kidney proximal tubule [PDF]
Proceedings of the National Academy of Sciences, 2004 Normal variations in glomerular filtration induce proportional changes in proximal tubule Na + reabsorption. This “glomerulotubular balance” derives from flow dependence of Na + uptake across luminal cell membranes; however, the underlying physical mechanism is unknown. Our hypothesis is that
Zhaopeng, Du +5 more
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Kidney Proximal Tubule GLUT2—More than Meets the Eye
Cells, 2022 Tubulopathy plays a central role in the pathophysiology of diabetic kidney disease (DKD). Under diabetic conditions, the kidney proximal tubule cells (KPTCs) are exposed to an extensive amount of nutrients, most notably glucose; these nutrients deteriorate KPTCs function and promote the development and progression of DKD.
Majdoleen Ahmad +6 more
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Histological Characteristics of the Kidney in Mongolian Gerbils of Different Ages
Shiyan dongwu yu bijiao yixue, 2023 ObjectiveTo explore the histological characteristics of the kidney in Mongolian gerbils of different ages.MethodsTen Mongolian gerbils of 2, 6, and 12 months old (half male and half female) were selected.
LU Lingqun +4 more
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Colocalization of GLUT2 glucose transporter, sodium/glucose cotransporter, and gamma-glutamyl transpeptidase in rat kidney with double-peroxidase immunocytochemistry. [PDF]
, 1992 Glucose is reabsorbed from the glomerular filtrate in the proximal segment of the renal tubule in two stages. The first stage is uphill transport across the brush border membrane by Na(+)-glucose cotransport and the second stage is downhill transport ...
Cramer, SC +3 more
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Scientific Reports, 2018 Fibroblast growth factor 23 (FGF23) plays critical roles in phosphate handling and vitamin D metabolism in the kidney. However, the effector cells of FGF23 in the kidney remain unclear.
Ai Takeshita +4 more
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Sex-Specific Computational Models of Kidney Function in Patients With Diabetes
Frontiers in Physiology, 2022 The kidney plays an essential role in homeostasis, accomplished through the regulation of pH, electrolytes and fluids, by the building blocks of the kidney, the nephrons.
Sangita Swapnasrita +3 more
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