The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506: Clinical significance and comparison with cyclosporine [PDF]
, 1993 The histopathological changes in 51 renal allograft biopsies from patients immunosuppressed with FK506 were compared with those seen in 30 needle biopsies obtained from patients on cyclosporine.
Demetris, AJ +4 more
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Biionic potentials in the proximal tubule of Necturus kidney [PDF]
The Journal of Physiology, 1973 1. Biionic potentials were studied in the proximal tubule of the doubly perfused Necturus kidney and subsequently analysed by means of an equivalent electrical circuit.2. Luminal membrane resistance was found to be at least 3 times greater than peritubular membrane resistance.3.
openaire +3 more sources
Solvent drag measurement of transcellular and basolateral membrane NaCl reflection coefficient in kidney proximal tubule. [PDF]
, 1991 The NaCl reflection coefficient in proximal tubule has important implications for the mechanisms of near isosmotic volume reabsorption. A new fluorescence method was developed and applied to measure the transepithelial (sigma NaClTE) and basolateral ...
Fushimi, K, Shi, LB, Verkman, AS
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Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane [PDF]
, 2012 Despite being engineered to avoid renal clearance, many cationic polymer (polycation)-based siRNA nanoparticles that are used for systemic delivery are rapidly eliminated from the circulation.
Andrews +26 more
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Enhancement of HGF-induced tubulogenesis by endothelial cell-derived GDNF [PDF]
, 2019 学位記番号 ...
Nakasatomi, Masao +2 more
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An emerging protagonist: Sodium Glucose Co-transporters (SGLTs) as a burgeoning target for the treatment of diabetes mellitus [PDF]
, 2012 Contemporary therapies to rationalize the hyperglycaemia in type 2 diabetes mellitus (T2DM) generally involve insulin-dependent mechanisms and lose their effectiveness as pancreatic b-cell function decreases to a greater extent. The kidney emerges out as
Danish Ahmed +3 more
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Continuous growth of proximal tubular kidney epithelial cells in hormone-supplemented serum-free medium. [PDF]
, 1982 An epithelial cell line from pig kidney (LLC-PK1) with properties of proximal tubular cells can be maintained indefinitely in hormone-supplemented serum-free medium. Continuous growth requires the presence of seven factors: transferrin, insulin, selenium,
Chuman, L +3 more
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Clinical review: Biomarkers of acute kidney injury: where are we now? [PDF]
, 2012 The recognition that acute kidney injury (AKI) is a significant independent risk factor for morbidity and mortality has resulted in a substantial number of publications over the past 5 years or more.
Forni, LG, Ostermann, M, Philips, BJ
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MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy [PDF]
, 2017 Renal fibrosis is a common complication of diabetic nephropathy and is a major cause of end-stage renal disease. Despite the suggested link between renal fibrosis and microRNA (miRNA) dysregulation in diabetic nephropathy, the identification of the ...
Benigni, Ariela +11 more
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Urine metabolomic analysis to detect metabolites associated with the development of contrast induced nephropathy. [PDF]
, 2016 ObjectiveContrast induced nephropathy (CIN) is a result of injury to the proximal tubules. The incidence of CIN is around 11% for imaging done in the acute care setting.
Diercks, Deborah B +3 more
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