Results 31 to 40 of about 73,145 (294)
Axial differences in endocytosis along the kidney proximal tubule [PDF]
American Journal of Physiology-Renal Physiology, 2019 The proximal tubule (PT) reabsorbs filtered proteins via receptor-mediated endocytosis to prevent energetically inefficient wasting in the urine. Recent intravital imaging studies have suggested that protein reabsorption occurs in early (S1) segments, which have a very high capacity.
Polesel, Marcello, Hall, Andrew M
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Biochemical heterogeneity of arginine metabolism along kidney proximal tubules
Kidney International, 1996 By using an in vitro single tubule micromethod of high specificity, in four different species of mammals it has been observed that (a) arginine synthesis from citrulline (arginine synthase activity, E.C. 6.3.4.5 and E.C. 4.3.2.1) is restricted to the early portions of proximal convoluted tubules, whereas (b) urea production from arginine (arginase ...
Morel, François +2 more
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Changes in renal WT-1 expression preceding hypertension development [PDF]
, 2016 Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica +8 more
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Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]
, 2017 Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola +3 more
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Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis [PDF]
, 2017 Removal of renal mass stimulates anatomical and functional adaptations in the surviving nephrons, including elevations in single-nephron glomerular filtration rate (SNGFR) and tubular hypertrophy. A goal of this study is to assess the extent to which the
Edwards, Aurelie +2 more
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Frontiers in Physiology, 2021 Hypertension is well recognized to be the most important risk factor for cardiovascular diseases, stroke, and end-stage kidney failure. A quarter of the world’s adult populations and 46% of the US adults develop hypertension and currently require ...
Xiao Chun Li +3 more
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Cells, 2023 Autophagy is involved in the development of diabetic kidney disease (DKD), the leading cause of end-stage renal disease. The Fyn tyrosine kinase (Fyn) suppresses autophagy in the muscle. However, its role in kidney autophagic processes is unclear.
Ryota Uehara +7 more
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Redox BiologyThere is a large body of evidence implicating mitochondrial reactive oxygen species (ROS) overproduction and oxidative stress in the development of diabetic kidney disease and the deficiency of mitochondrial antioxidant systems in the kidney, such as ...
Inez A. Trambas +14 more
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Quantitative morphology of renal cortical structures during compensatory hypertrophy [PDF]
, 1998 The compensatory hypertrophy in different renal cortical structures was studied in rats 10 and 21 days after unilateral nephrectomy (UNX). Quantitative morphological/stereological analysis revealed significant increases in total renal cortical volume ...
Beck, Franz-X. +4 more
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Current Research in PhysiologyKidney Injury Molecule-1 (KIM-1) has emerged as a significant biomarker and mechanistic player in kidney pathology, particularly in acute kidney injury (AKI).
Ping L. Zhang, Ming-Lin Liu
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