Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice
Advanced Science, EarlyView.Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu +14 more
wiley +1 more source
Rearrangement of rat kidney sialoglycans during postnatal morphogenesis and in streptozotocin-induced diabetic nephropathia [PDF]
Морфологія, 2009 9 lectins with different carbohydrate affinities (SNA, WGA, RCA, PNA, VAA, CABA-2, SJA, SBA, HPA) were used for histochemical investigation of rat kidney glycoconjugates during postnatal morphogenesis and in streptozotocin-induced diabetes mellitus ...
Ambarova N.O.
doaj
The kidney transcriptome and proteome defined by transcriptomics and antibody-based profiling.
PLoS ONE, 2014 To understand renal functions and disease, it is important to define the molecular constituents of the various compartments of the kidney. Here, we used comparative transcriptomic analysis of all major organs and tissues in the human body, in combination
Masato Habuka +9 more
doaj +1 more source
Sodium Movement across Single Perfused Proximal Tubules of Rat Kidneys [PDF]
, 1964 Gerhard Giebisch +4 more
openalex +1 more source
Bioprinted Organoids: An Innovative Engine in Biomedicine
Advanced Science, EarlyView.Bioprinted organoids refer to either the printing of stem cells into tissue shape and subsequent differentiate into organoids, or assembling induced organoids as bioinks to replicate native organ. It enables the creation of miniaturized organs with complex architectures and physiological functions, potentially enhancing reproducibility, throughput, and
Zhengwei Li +11 more
wiley +1 more source
Journal of Diabetes Research, 2018 The kidney is an insulin-sensitive organ involved in glucose homeostasis. One major effect of insulin is to induce glycogen storage in the liver and muscle.
Romina Bertinat +7 more
doaj +1 more source
Associations of CKD risk factors and longitudinal changes in urine biomarkers of kidney tubules among women living with HIV. [PDF]
BMC Nephrol, 2021 Muiru AN +15 more
europepmc +1 more source
A Microperfusion Study of Bicarbonate Accumulation in the Proximal Tubule of the Rat Kidney* [PDF]
, 1967 Norman Bank, Hagop S. Aynedjian
openalex +1 more source
Regulating Enzyme Activity via Microaggregates Mediated by Phase Separation
Advanced Science, EarlyView.An enzyme‐sequestration strategy for combating postoperative pancreatic fistula (POPF) is developed, employing a D‐peptide called DPMD to induce liquid–solid phase separation (LSPS) of pancreatic proteases. This LSPS‐driven microaggregate approach effectively isolates trypsin and chymotrypsin from their substrates, thereby reducing pancreatic fluid ...
Yang Wang +7 more
wiley +1 more source
LIPOPROTEIN GRANULES IN THE CORTICAL COLLECTING TUBULES OF MOUSE KIDNEY [PDF]
, 1961 Fritz Miller
openalex +1 more source