Results 131 to 140 of about 134,704 (353)

WOx Nanosheets Enhance Acute Kidney Injury Therapy Through Geometry‐Improved Targeting and Antioxidant Properties

open access: yesAggregate, EarlyView.
Three representative WOx nanostructures, nanodot, nanowire, and nanosheet, have been bottom‐up synthesized to investigate the “structure‐function” correlations in the AKI treatment, the results of which demonstrated that nanosheet is the most promising candidate for AKI management among three geometries because of its intrinsic renal accumulation, long‐
Yi Wang   +11 more
wiley   +1 more source

Compound Heterozygous Variants in ZSWIM7 Gene Linked to Infertility and Its Role in Gonadal Development

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini   +8 more
wiley   +1 more source

PENGARUH ASPARTAM TERHADAP KADAR KREATININ SERUM DAN STRUKTUR HISTOLOGIS REN MENCIT (Mus Musculus L.) STRAIN SWISS [PDF]

open access: yes, 2007
Umi Barokah Irawati. 2006. THE EFFECT OF ASPARTAME TO THE SERUM CREATININE LEVEL AND HISTOLOGIC STRUCTURE OF KIDNEY IN MICE (Mus musculus L.) STRAIN SWISS. Departement of Biology. Faculty of Mathematics and Natural Science.
Irawati, Umi Barokah
core  

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

open access: yesAdvanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu   +3 more
wiley   +1 more source

Proximal tubular deletion of superoxide dismutase-2 reveals disparate effects on kidney function in diabetes

open access: yesRedox Biology
There is a large body of evidence implicating mitochondrial reactive oxygen species (ROS) overproduction and oxidative stress in the development of diabetic kidney disease and the deficiency of mitochondrial antioxidant systems in the kidney, such as ...
Inez A. Trambas   +14 more
doaj  

Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud [PDF]

open access: yes, 1995
Mice homozygous for the recessive limb deformity (ld) mutation display both limb and renal defects. The limb defects, oligodactyly and syndactyly, have been traced to improper differentiation of the apical ectodermal ridge (AER) and shortening of the ...
Chan, David C.   +2 more
core  

Efficacy and safety of dotinurad versus febuxostat for the treatment of gout: a randomised, multicentre, double‐blind, phase 3 trial in China

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicentre, randomised, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad
Jia Sun   +19 more
wiley   +1 more source

Home - About - Disclaimer - Privacy