Results 51 to 60 of about 134,704 (353)

Pkd2 dosage influences cellular repair responses following ischemia-reperfusion injury [PDF]

, 2009
Autosomal dominant polycystic kidney disease (ADPKD) results from mutations in either PKD1 or PKD2 and accounts for 10% of all patients on renal replacement therapy. The kidney disease phenotype is primarily characterized by cyst formation, but there are
Haylor, J.L., McDaid, J.P., Ong, A.C.M., Prasad, S., Tam, F.W.K.   +4 more
core   +2 more sources

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

Advanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers, Erik J. Slootweg, Ferdinand C. O. Los, Patricia Y. W. Dankers   +3 more
wiley   +1 more source

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism

Scientific Reports, 2018
Fibroblast growth factor 23 (FGF23) plays critical roles in phosphate handling and vitamin D metabolism in the kidney. However, the effector cells of FGF23 in the kidney remain unclear.
Ai Takeshita, Kazuki Kawakami, Kenryo Furushima, Masayasu Miyajima, Kazushige Sakaguchi   +4 more
doaj   +1 more source

MDM2 prevents spontaneous tubular epithelial cell death and acute kidney injury [PDF]

, 2016
Murine double minute-2 (MDM2) is an E3-ubiquitin ligase and the main negative regulator of tumor suppressor gene p53. MDM2 has also a non-redundant function as a modulator of NF-kB signaling. As such it promotes proliferation and inflammation.
Anders, Hans-Joachim, Ebrahim, Martrez, Endlich, Nicole, Fleckinger, Kristina, Kotb, Ahmed M, Li, Moying, Liapis, Helen, Molnar, Jakob, Popper, Bastian, Siegerist, Florian, Thomasova, Dana   +10 more
core   +2 more sources

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Knockdown of TMEM30A in renal tubular epithelial cells leads to reduced glucose absorption

BMC Nephrology, 2023
The kidney reabsorbs large amounts of glucose through Na+-glucose cotransporter 2 (SGLT2). P4-ATPase acts together with the β-subunit TMEM30A to mediate the asymmetric distribution of phosphatidylserine (PS), phosphatidylethanolamine (PE), and other ...
Sipei Chen, Xinrou Song, Qiong Xiao, Li Wang, Xianjun Zhu, Yang Zou, Guisen Li   +6 more
doaj   +1 more source

A study of the lipoid content of the kidney tubule [PDF]

American Journal of Anatomy, 1920
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openaire   +2 more sources

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Morfometría de cortes histológicos de los túbulos renales normales en una muestra de humanos adultos

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Fundamento: los túbulos renales normales se han descrito por morfometría, lo que permite “reconstruir” en tercera dimensión la forma y el tamaño del espécimen estudiado.Objetivo: caracterizar la magnitud de los túbulos renales normales en humanos adultos,
Miosotis de Lourdes Fernández Lastre, Iraldo Mederos Pérez, Yardelys Rego Juhe, Sandor Varela Iraola, Tamara Caraballoso Recio   +4 more
doaj  

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury. [PDF]

, 2019
Acute kidney injury (AKI) can be fatal and is a well-defined risk factor for the development of chronic kidney disease. Group 2 innate lymphoid cells (ILC2s) are innate producers of type-2 cytokines and are critical regulators of homeostasis in ...
Cameron, Guy JM, Cautivo, Kelly M, Deshpande, Aniruddh V, Foster, Paul S, Hansbro, Philip M, Jiang, Simon H, Loering, Svenja, McKenzie, Andrew NJ, Molofsky, Ari B, Starkey, Malcolm R   +9 more
core   +4 more sources