Results 81 to 90 of about 127,828 (193)

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue   +7 more
wiley   +1 more source

Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud [PDF]

open access: yes, 1995
Mice homozygous for the recessive limb deformity (ld) mutation display both limb and renal defects. The limb defects, oligodactyly and syndactyly, have been traced to improper differentiation of the apical ectodermal ridge (AER) and shortening of the ...
Chan, David C.   +2 more
core  

Actinidia spp. (Kiwifruit): A Comprehensive Review of Its Nutraceutical Potential in Disease Mitigation and Health Enhancement

open access: yesFood Frontiers, EarlyView.
Nutraceutical Potential in Disease Mitigation and Health Enhancement of Actinidia spp. (Kiwifruit) ABSTRACT This review offers an in‐depth exploration of the Actinidia species (kiwifruit) nutritional composition, the pivotal role of its primary bioactive compounds, and their potential applications across the aforementioned health concerns. Furthermore,
Allah Rakha   +7 more
wiley   +1 more source

What Does Iron Mean to an Oligodendrocyte?

open access: yesGlia, EarlyView.
ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions. The brain has the highest rate of energy consumption, and within the brain, oligodendrocytes have the highest level of oxidative metabolism per volume. Oligodendrocytes also stain the strongest for iron.
Quinn W. Wade, James R. Connor
wiley   +1 more source

Urinary Peptide Levels in Patients with Chronic Renal Failure [PDF]

open access: yes, 2010
Introduction: Peptide levels in urine are found to be decreased in renal failure. In the current study urinary peptide levels were determined in chronic renal failure (CRF) patients.
M, Supriya   +3 more
core  

Genetic Variability in Cisplatin Metabolism in Kidney Injury in Patients With Head and Neck Squamous Cell Carcinoma Undergoing Definitive Chemoradiotherapy

open access: yesHead &Neck, EarlyView.
ABSTRACT Background This study investigated the roles of single nucleotide variants (SNVs) in genes of CDDP metabolism and their association with kidney dysfunction in patients with head and neck squamous cell carcinoma (HNSCC). Methods A total of 109 patients with locally advanced HNSCC, treated with CDDP, had renal function evaluated by serum ...
Ericka Francislaine Dias Costa   +4 more
wiley   +1 more source

The influence of microbiome‐derived amino acids metabolites in shaping the glioma immunosuppressive microenvironment

open access: yesInterdisciplinary Medicine, EarlyView.
Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma   +10 more
wiley   +1 more source

Cloning of mouse integrin alphaV cDNA and role of the alphaV-related matrix receptors in metanephric development. [PDF]

open access: yes, 1996
Metanephrogenesis has been a long-standing model to study cell-matrix interactions. A number of adhesion molecules, including matrix receptors (i.e., integrins), are believed to be involved in such interactions.
Kanwar, YS   +6 more
core  

Ruthenium Nanozyme@Magnesium silicate nanosheets encapsuled in microneedle patches promote repair of radiation‐induced skin defects by remodeling pathological environment

open access: yesInterdisciplinary Medicine, EarlyView.
In this work, we introduce a novel composite microneedle (MN) patch that integrates ruthenium‐loaded magnesium silicate nanosheets (MSR) as a multifaceted therapeutic platform with oxidative stress mitigation, ROS generation inhibition and cellular signaling pathways restoration for treating RISD.
Zhongyi Sun   +11 more
wiley   +1 more source

High-resolution laser ablation-inductively coupled plasma-mass spectrometry imaging of cisplatin-induced nephrotoxic side effects [PDF]

open access: yes, 2016
Cuyckens, Filip   +5 more
core   +1 more source

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