Results 71 to 80 of about 639,100 (318)
Invariant Natural Killer T Cells
Antibodies, 2013 Invariant Natural killer T cell (iNKT cells) are a subset of T cells, which are narrowly defined as a T cell lineage expressing a semi-invariant CD1d-restricted T cell Receptors (TCRs) composed by Vα24-Jα18/Vβ11 in human, and Vα14-Jα18/Vβ8,Vβ7, and Vβ2 ...
Antonella Cianferoni
doaj +1 more source
Estimating the number of serial killers that were never caught [PDF]
arXiv, 2021 Many serial killers commit tens of murders. At the same time inter-murder intervals can be decades long. This suggests that some serial killers can die of an accident or a disease, having been never caught. We use the distribution of the killers by the number of murders, the distribution of the length of inter-murder intervals and USA life tables to ...
arxiv
A team effort: natural killer cells on the first leg of the tumor immunity relay race [PDF]
, 2018 Recent work by Böttcher and colleagues defines a new role for Natural Killer cells in the anti-tumor immune response, arriving early into the tumor microenvironment before passing the baton to DC1 dendritic cells.
Duong, Ellen +2 more
core +1 more source
Natural Killer Cells in the Lungs
Frontiers in Immunology, 2019 The lungs, a special site that is frequently challenged by tumors, pathogens and other environmental insults, are populated by large numbers of innate immune cells. Among these, natural killer (NK) cells are gaining increasing attention. Recent studies have revealed that NK cells are heterogeneous populations consisting of distinct subpopulations with ...
Jingjing Cong +4 more
openaire +4 more sources
Natural Killer Cells in Psoriasis [PDF]
Journal of Innate Immunity, 2011 Psoriasis is one of the most common immune-mediated disorders. There is evidence that it is mediated by Th1 and, more recently, Th17 cells. The cytokine pattern, particularly the dominance of TNF-α, implicates the innate immune system in psoriasis pathogenesis. Of the many components of the innate immune system known to be involved in psoriatic lesions,
Brian Kirby +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Haematologica, 2009 The concept of tumor immunosurveillance has raised prospects for natural killer cell-based immunotherapy of human cancer. The cure of acute myeloid leukemia may depend on eradication of leukemic stem cells, the self-renewing component of leukemia ...
Ulrich Langenkamp +6 more
doaj +1 more source
A Bayesian Feature Allocation Model for Identification of Cell Subpopulations Using Cytometry Data [PDF]
arXiv, 2020 A Bayesian feature allocation model (FAM) is presented for identifying cell subpopulations based on multiple samples of cell surface or intracellular marker expression level data obtained by cytometry by time of flight (CyTOF). Cell subpopulations are characterized by differences in expression patterns of makers, and individual cells are clustered into
arxiv
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
Einstein (São Paulo), 2023 Objective To determine the role of the AKT pathway in the regulating of natural Killer-induced apoptosis of acute myeloid leukemia cells and to characterize the associated molecular mechanisms.
Sofia Mônaco Gama +7 more
doaj +1 more source