Results 161 to 170 of about 3,771,587 (392)

Bruton’s tyrosine kinase inhibition effectively protects against human IgE-mediated anaphylaxis [PDF]

, 2020
Melanie C. Dispenza, Rebecca A. Krier-Burris, Krishan D. Chhiba, Bradley J. Undem, Piper A. Robida, Bruce S. Bochner   +5 more
openalex   +1 more source

Retinal Delivery of the Protein Kinase C-β Inhibitor Ruboxistaurin Using Non-Invasive Nanoparticles of Polyamidoamine Dendrimers [PDF]

, 2022
Rehab A. Alshammari, Fadilah Sfouq Aleanizy, Amal Aldarwesh, Fulwah Yahya Alqahtani, Wael A. Mahdi, Bushra T. AlQuadeib, Qamraa H. Alqahtani, Nazrul Haq, Faiyaz Shakeel, Hosam Gharib Abdelhady, Ibrahim A. Alsarra   +10 more
openalex   +1 more source

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.

New England Journal of Medicine, 2010
E. Kwak, Y. Bang, D. Camidge, A. Shaw, B. Solomon, Robert G. Maki, Sai-Hong Ignatius Ou, B. Dezube, P. Jänne, Daniel, B. Costa, M. Varella-Garcia, W. Kim, Thomas J. Lynch, P. Fidias, Hannah Stubbs, J. Engelman, V. Lecia, Sequist, Weiwei Tan, L. Gandhi, M. Mino‐Kenudson, Greg C. Wei, S. M. Shreeve, M. Ratain, Jeffrey, Settleman, James G. Christensen, D. Haber, K. Wilner, R. Salgia, Geoffrey I. Shapiro, J. Clark, A. Iafrate   +33 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The C4 hydroxyl group of phorbol esters is not necessary for protein kinase C binding

, 2001
Minoru Tanaka, Kazuhiro Irie, Yu Nakagawa, Yoshimasa Nakamura, Hajime Ohigashi, Paul A. Wender   +5 more
openalex   +1 more source

IL-26 mediates epidermal growth factor receptor-tyrosine kinase inhibitor resistance through endoplasmic reticulum stress signaling pathway in triple-negative breast cancer cells [PDF]

, 2021
Takumi Itoh, Ryo Hatano, Yoshiya Horimoto, Taketo Yamada, Dan Song, Haruna Otsuka, Yûki Shirakawa, Shuji Mastuoka, Noriaki Iwao, Thomas M. Aune, Nam H. Dang, Yutaro Kaneko, Ko Okumura, Chikao Morimoto, Kei Ohnuma   +14 more
openalex   +1 more source

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions.

Endocrine reviews, 2001
G. Pearson, Fred L Robinson, T. Gibson, Bing-e Xu, M. Karandikar, K. Berman, M. Cobb   +6 more
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Global Effects of Kinase Inhibitors on Signaling Networks Revealed by Quantitative Phosphoproteomics [PDF]

, 2009
Cuiping Pan, Jesper V. Olsen, Henrik Daub, Matthias Mann   +3 more
openalex   +1 more source

Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 [PDF]

, 2020
openaire   +1 more source