Results 41 to 50 of about 3,631,373 (391)
C24H25NO5, triclinic, P1̄, a = 9.2625(8) Å, b = 10.5974(10) Å, c = 11.7431(11) Å, α = 77.836(8)°, β = 87.564(8)°, γ = 66.951(9)°, V = 1035.83(17) Å3, Z = 2, Rgt(F) = 0.0404, wRref(F2) = 0.0985, T = 107.5 K.
Tan Hong-Bo, Meng Jiang-Ping
doaj +1 more source
Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus [PDF]
Autophosphorylation of calcium/calmodulin-dependent protein kinase II (CaMKII) at threonine-286 produces Ca2+-independent kinase activity and has been proposed to be involved in induction of long-term potentiation by tetanic stimulation in the ...
Harris, Kristen M.+4 more
core +2 more sources
C27H22BrClN2O5, triclinic, P1̄, a = 6.8549(4) Å, b = 13.2863(12) Å, c = 14.3690(13) Å, α = 85.944(7)°, β = 84.882(6)°, γ = 89.932(6)°, V = 1300.18(18) Å3, Z = 2, Rgt(F) = 0.0655, wRref(F2) = 0.1841, T = 293(2) K.
Meng Jiang Ping, Lei Jie
doaj +1 more source
Aurora-A kinase, a key mitosis regulator, is expressed in a cell cycle-dependent manner and has an essential role in maintaining chromosomal stability and the normal progression of the cell through mitosis.
Omeima Abdullah
doaj +1 more source
Differential regulation of anti-inflammatory genes by p38 MAP kinase and MAP kinase kinase 6. [PDF]
BackgroundConventional p38α inhibitors have limited efficacy in rheumatoid arthritis, possibly because p38 blockade suppresses the counter-regulatory mechanisms that limit inflammation.
Boyle, David L+3 more
core +3 more sources
Metabolic Kinases Moonlighting as Protein Kinases [PDF]
Protein kinases regulate every aspect of cellular activity, whereas metabolic enzymes are responsible for energy production and catabolic and anabolic processes. Emerging evidence demonstrates that some metabolic enzymes, such as pyruvate kinase M2 (PKM2), phosphoglycerate kinase 1 (PGK1), ketohexokinase (KHK) isoform A (KHK-A), hexokinase (HK), and ...
Zhimin Lu, Zhimin Lu, Tony Hunter
openaire +2 more sources
The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src [PDF]
The transmembrane receptor 'ROR2' resembles members of the receptor tyrosine kinase family of signalling receptors in sequence but its' signal transduction mechanisms remain enigmatic.
A Schambony+32 more
core +5 more sources
Prokaryotic Diacylglycerol Kinase and Undecaprenol Kinase [PDF]
Prokaryotic diacylglycerol kinase (DAGK) and undecaprenol kinase (UDPK) are the lone members of a family of multispan membrane enzymes that are very small, lack relationships to any other family of proteins—including water soluble kinases—and exhibit an unusual structure and active site architecture.
Charles R. Sanders, Wade D. Van Horn
openaire +3 more sources
Annotation matters: validating the discovery of cancer drivers
Advanced sequencing techniques have helped unveil numerous new, potential cancer driver mutations. However, manual curation and analysis of gene and protein annotation are essential to verify such discoveries.
Marta Rodríguez-Martínez+1 more
doaj +1 more source
Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R [PDF]
Background: Vaccinia virus gene B1R encodes a erine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia virus protein H5R, proteins that become phosphorylated during infection.
Beaud, G.+4 more
core +3 more sources