Results 41 to 50 of about 3,631,373 (391)

Crystal structure of diethyl 2-(4-methoxyphenyl)-1-phenyl-1,2-dihydropyridine-3,5-dicarboxylate, C24H25NO5

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2019
C24H25NO5, triclinic, P1̄, a = 9.2625(8) Å, b = 10.5974(10) Å, c = 11.7431(11) Å, α = 77.836(8)°, β = 87.564(8)°, γ = 66.951(9)°, V = 1035.83(17) Å3, Z = 2, Rgt(F) = 0.0404, wRref(F2) = 0.0985, T = 107.5 K.
Tan Hong-Bo, Meng Jiang-Ping
doaj   +1 more source

Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus [PDF]

open access: yes, 1997
Autophosphorylation of calcium/calmodulin-dependent protein kinase II (CaMKII) at threonine-286 produces Ca2+-independent kinase activity and has been proposed to be involved in induction of long-term potentiation by tetanic stimulation in the ...
Harris, Kristen M.   +4 more
core   +2 more sources

Crystal structure of (E)-N-(2-(benzylamino)-2-oxo-1-(4-oxo-4H-chromen-3-yl)ethyl)-N-(4-bromophenyl)-3-chloroacrylamide hydrate, C27H22BrClN2O5

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2018
C27H22BrClN2O5, triclinic, P1̄, a = 6.8549(4) Å, b = 13.2863(12) Å, c = 14.3690(13) Å, α = 85.944(7)°, β = 84.882(6)°, γ = 89.932(6)°, V = 1300.18(18) Å3, Z = 2, Rgt(F) = 0.0655, wRref(F2) = 0.1841, T = 293(2) K.
Meng Jiang Ping, Lei Jie
doaj   +1 more source

Design, Synthesis, and Biochemical Evaluation of New Triazole Derivatives as Aurora-A Kinase Inhibitors

open access: yesMolecules, 2021
Aurora-A kinase, a key mitosis regulator, is expressed in a cell cycle-dependent manner and has an essential role in maintaining chromosomal stability and the normal progression of the cell through mitosis.
Omeima Abdullah
doaj   +1 more source

Differential regulation of anti-inflammatory genes by p38 MAP kinase and MAP kinase kinase 6. [PDF]

open access: yes, 2014
BackgroundConventional p38α inhibitors have limited efficacy in rheumatoid arthritis, possibly because p38 blockade suppresses the counter-regulatory mechanisms that limit inflammation.
Boyle, David L   +3 more
core   +3 more sources

Metabolic Kinases Moonlighting as Protein Kinases [PDF]

open access: yesTrends in Biochemical Sciences, 2018
Protein kinases regulate every aspect of cellular activity, whereas metabolic enzymes are responsible for energy production and catabolic and anabolic processes. Emerging evidence demonstrates that some metabolic enzymes, such as pyruvate kinase M2 (PKM2), phosphoglycerate kinase 1 (PGK1), ketohexokinase (KHK) isoform A (KHK-A), hexokinase (HK), and ...
Zhimin Lu, Zhimin Lu, Tony Hunter
openaire   +2 more sources

The deleted in brachydactyly B domain of ROR2 is required for receptor activation by recruitment of Src [PDF]

open access: yes, 2007
The transmembrane receptor 'ROR2' resembles members of the receptor tyrosine kinase family of signalling receptors in sequence but its' signal transduction mechanisms remain enigmatic.
A Schambony   +32 more
core   +5 more sources

Prokaryotic Diacylglycerol Kinase and Undecaprenol Kinase [PDF]

open access: yesAnnual Review of Biophysics, 2012
Prokaryotic diacylglycerol kinase (DAGK) and undecaprenol kinase (UDPK) are the lone members of a family of multispan membrane enzymes that are very small, lack relationships to any other family of proteins—including water soluble kinases—and exhibit an unusual structure and active site architecture.
Charles R. Sanders, Wade D. Van Horn
openaire   +3 more sources

Annotation matters: validating the discovery of cancer drivers

open access: yesMolecular & Cellular Oncology, 2020
Advanced sequencing techniques have helped unveil numerous new, potential cancer driver mutations. However, manual curation and analysis of gene and protein annotation are essential to verify such discoveries.
Marta Rodríguez-Martínez   +1 more
doaj   +1 more source

Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R [PDF]

open access: yes, 2000
Background: Vaccinia virus gene B1R encodes a erine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia virus protein H5R, proteins that become phosphorylated during infection.
Beaud, G.   +4 more
core   +3 more sources

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