Results 131 to 140 of about 44,237 (280)

Performance Evaluation of a New HRD Assay (HRDsig) in Ovarian Carcinomas in Australia

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
In this study we have evaluated the performance of a new HRD assay (HRDsig) against two accredited HRD assays, as well as against commercial controls and inter‐laboratory comparison samples. HRDsig has demonstrated a high concordance rate for determining HRD status in ovarian carcinomas.
Pranav Dorwal   +11 more
wiley   +1 more source

On the possibility of yet a third kinetochore system in the protist phylum Euglenozoa

open access: yesmBio
Transmission of genetic material from one generation to the next is a fundamental feature of all living cells. In eukaryotes, a macromolecular complex called the kinetochore plays crucial roles during chromosome segregation by linking chromosomes to ...
Corinna Benz   +6 more
doaj   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Predictors of systemic sclerosis patients with interstitial lung disease progression: A retrospective study

open access: yesRheumatology &Autoimmunity, EarlyView.
The final systemic sclerosis patients with interstitial lung disease (SSc‐ILD) progression prediction model was composed of 6 significant risk factors: male, type 2 diabetes mellitus, pericardial effusion, anti‐Ro52, hypoproteinemia, and elevated C‐reactive protein. Our model demonstrated excellent prognostic utility.
Xi Cao   +6 more
wiley   +1 more source

Taxonomy and dated molecular phylogeny of Allium oreophilum sensu lato (A. subg. Porphyroprason) uncover a surprising number of cryptic taxa

open access: yesTAXON, EarlyView.
Abstract Allium oreophilum, hitherto the representative of the monotypic A. subg. Porphyroprason from the second evolutionary lineage of Allium, is studied in detail. Over about 150 years, A. oreophilum was regarded as a somewhat polymorphous species with two synonyms, all described in the 19th century.
Nikolai Friesen   +13 more
wiley   +1 more source

Upregulation of ST3GAL5 predicts suppression of malignant biological behavior in bladder cancer

open access: yesUroPrecision, EarlyView.
Abstract Background Bladder cancer (BLCA) is the most prevalent malignancy in the urinary tract system, while ST3GAL5 is a protein‐coding gene that catalyzes the formation of ganglioside monosialodihexosylganglioside 3 (GM3) synthase. GM3 synthase has been reported to significantly influence the malignant process of various cancers.
Song Ou‐Yang   +3 more
wiley   +1 more source

The Prevalence and Severity of Pain in Patients With Systemic Sclerosis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT We investigated pain prevalence and severity in systemic sclerosis (SSc) and patient–physician perceptions. This was an internet‐based survey that compared perceptions of pain type, location, severity, associated factors between patients with SSc and physicians, and pain treatment prescription patterns in Japan in March 2023.
Sei‐ichiro Motegi   +6 more
wiley   +1 more source

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