Results 251 to 260 of about 40,318 (318)

Clinical Laboratory Experience With Prenatal cfDNA Screening in Triplet Pregnancies

Prenatal Diagnosis, Volume 45, Issue 6, Page 705-712, June 2025.
ABSTRACT Objective Prenatal cfDNA screening is the most sensitive and specific screen for common aneuploidies in singleton and twin pregnancies and has been endorsed by several professional societies as a first‐tier screen or contingent screen. However, data for triplet pregnancies is lacking, as these pregnancies are relatively uncommon and obtaining ...
Erica Soster, Brittany Dyr, Samantha Caldwell, Savannah Moore, Eyad Almasri, Hany Magharyous, Juan‐Sebastian Saldivar, Phillip Cacheris   +7 more
wiley   +1 more source

AURKA controls oocyte spindle assembly checkpoint and chromosome alignment by HEC1 phosphorylation. [PDF]

Life Sci Alliance
Blengini CS, Tang S, Mendola RJ, Garrisi GJ, Swain JE, Schindler K.   +5 more
europepmc   +1 more source

Proportion of parental genomes in hybrids Allium cepa × A. roylei determines which one becomes dominant

The Plant Genome, Volume 18, Issue 2, June 2025.
Abstract Interspecific hybridization leads to complex interactions between the parental genomes, often in the form of genome dominance, where one genome prevails over the other. This phenomenon has been attributed to differential chromosome behavior during meiotic division and may involve either female or male meiosis, or both.
David Kopecký, Martin Duchoslav, Olga Scholten, Jana Kneřová, Marek Szecówka   +4 more
wiley   +1 more source

KIF2C condensation concentrates PLK1 and phosphorylated BRCA2 on kinetochore microtubules in mitosis. [PDF]

Nucleic Acids Res
Skobelkina A, Julien M, Jeannin S, Miron S, Egger T, Chaaban R, Bouvignies G, Alghoul E, Ghouil R, Friel C, Busso D, Cañas JC, Theillet FX, Le Bars R, Carreira A, Constantinou A, Basbous J, Zinn-Justin S.   +17 more
europepmc   +1 more source

The SUV39 Family of H3K9 Methyltransferases in Skeletal Muscle Stem Cells

FASEB BioAdvances, Volume 7, Issue 6, June 2025.
The SUV39 family members are well known for methylating the Lysine 9 of the histone H3 (H3K9) in order to compact the chromatin and contributing to gene repression. We describe their active role in proliferating and differentiating muscle stem cells, how they prevent from inflammation and fibrosis during muscle regeneration and the future avenues ...
Pauline Garcia, Slimane Ait‐Si‐Ali, Fabien Le Grand   +2 more
wiley   +1 more source

HIV-1 Vif disrupts phosphatase feedback regulation at the kinetochore, leading to a pronounced pseudo-metaphase arrest. [PDF]

Elife
Ghone D, Evans EL, Bandini M, Stephenson KG, Sherer NM, Suzuki A.   +5 more
europepmc   +1 more source

Elevated Serum Immunoglobulin G1 Levels and Left Ventricular Diastolic Dysfunction in Anti‐Centromere Antibody–Positive Patients With Lower Extremity Arterial Disease: A Cross‐Sectional Study

The Journal of Dermatology, Volume 52, Issue 6, Page 1070-1077, June 2025.
ABSTRACT This cross‐sectional pilot study investigated the clinical characteristics of anti‐centromere antibody (ACA)–positive patients with below‐the‐knee arterial disease. Sixteen ACA‐positive patients (mean age 69 ± 10 years; 94% women) underwent contrast‐enhanced computed tomography evaluation, with arterial damage scored using the Global Limb ...
Tatsuya Shiraki, Hidetaka Kioka, Ikuko Ueda‐Hayakawa, Mitsuyoshi Takahara, Kyoko Tonomura, Aya Maekawa, Yorihisa Kotobuki, Yukihiro Enchi, Minako Ueda, Kosuke Takahari, Yasuharu Takeda, Daisuke Nakamura, Isamu Mizote, Tomohito Ohtani, Manabu Fujimoto, Yasushi Sakata   +15 more
wiley   +1 more source

Aurora B/AIR-2 regulates sister centromere resolution and CENP-A/HCP-3 organization to prevent merotelic attachments. [PDF]

J Mol Cell Biol
Wang Y, Yu Wong CY, Yuen KWY.
europepmc   +1 more source

Efficacy and Safety of Rituximab in Connective Tissue Disease‐Associated Thrombotic Thrombocytopenic Purpura/Thrombotic Microangiopathy

International Journal of Rheumatic Diseases, Volume 28, Issue 6, June 2025.
ABSTRACT Introduction This study examined the efficacy and safety of Rituximab (RTX) treatment in connective tissue disease (CTD)‐associated thrombocytopenic purpura (TTP) and thrombotic microangiopathy (TMA), using historical controls as comparators.
Naoaki Ohkubo, Shingo Nakayamada, Shunsuke Fukuyo, Yusuke Miyazaki, Yoshino Inoue, Hiroaki Tanaka, Yasuyuki Todoroki, Yoshiya Tanaka   +7 more
wiley   +1 more source

An Auxin Inducible Degradation System to Study Mklp2 Functions in MDCK Epithelial Cells

Biology of the Cell, Volume 117, Issue 6, June 2025.
This manuscript details the generation of an MDCK cell line in which the kinesin Mklp2 (KIF20A) is targeted at the endogenous level with an auxin inducible degradation (AID) tag and a GFP tag. This new tool facilitates the study of Mklp2 endogenous localization and constitutes a highly specific system for exploring Mklp2 functions at different stages ...
Morgane Rodriguez, Valérie Simon, Bénédicte Delaval, Benjamin Vitre   +3 more
wiley   +1 more source