Results 261 to 270 of about 117,673 (373)

A coordinated kinase and phosphatase network regulates Stu2 recruitment to yeast kinetochores [PDF]

Michael G. Stewart, Joseph S. Carrier, Jacob A. Zahm, Stephen C. Harrison, Matthew P. Miller   +4 more
openalex   +1 more source

Contemporary hybridization among Arabis floodplain species creates opportunities for adaptation

New Phytologist, Volume 249, Issue 3, Page 1542-1557, February 2026.
Summary Hybridization between closely related species is increasingly recognized as a major source of biodiversity. Yet, whether it can create advantageous trait combinations while purging harmful alleles remains unknown. To address this question, we studied Arabis nemorensis and Arabis sagittata, two endangered species that currently hybridize in a ...
Neda Rahnamae, Lukas Metzger, Lea Hördemann, Kevin Korfmann, Abdul Saboor Khan, Yasar Özoglan, Craig I. Dent, Samija Amar, Raúl Y. Wijfjes, Tahir Ali, Gregor Schmitz, Benjamin Stich, Aurelien Tellier, Juliette de Meaux   +13 more
wiley   +1 more source

Cell line-matched reference enables high-precision functional genomics. [PDF]

Nat Commun
Corda L, Volpe E, Dallali H, Di Tommaso E, Colantoni A, Guarracino A, Chittoor SS, Capulli M, Tassone E, Giunta S.   +9 more
europepmc   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, Volume 158, Issue 2, Page 333-341, 15 January 2026.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure

, 2017
Christina Hung, Barbara Volkmar, James D. Baker, Johann Bauer, Emanuela Gussoni, Stefan Hainzl, Alfred Klausegger, José M. Lorenzo, Ivana Mihalek, Olaf Rittinger, Mustafa Tekin, Julia E. Dallman, Olaf A. Bodamer   +12 more
openalex   +2 more sources

Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture

International Journal of Cancer, Volume 158, Issue 2, Page 409-422, 15 January 2026.
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert, Claire Vargas, Sina Jasmin Wille, Karsten Rippe   +3 more
wiley   +1 more source

CENcyclopedia: dynamic landscape of kinetochore architecture throughout the cell cycle. [PDF]

Nat Commun
Chen YC, Kilic E, Wang E, Rossman W, Suzuki A.   +4 more
europepmc   +1 more source

Correction of microtubule–kinetochore attachment errors: Mechanisms and role in tumor suppression

, 2011
Robin M. Ricke, Jan M. van Deursen
openalex   +2 more sources

DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis [PDF]

, 2017
Fei Ye, Eunchai Kang, Chuan Yu, Xuyu Qian, Fadi Jacob, Cong Yu, Mao Mao, Randy Y.C. Poon, Ji‐Eun Kim, Hongjun Song, Guo‐li Ming, Mingjie Zhang   +11 more
openalex   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, Volume 600, Issue 1, Page 83-98, January 2026.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source