Results 221 to 230 of about 6,579 (265)
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Atherosclerosis, 2005
The dynamic regulation of intravascular thrombus formation is central to our understanding of both acute and chronic atherosclerotic events. The initiation, modification and resolution of thrombus associated with eroded or unstable coronary plaques is critically dependent on the efficacy of endogenous fibrinolysis, a process that is itself reliant upon
Nicholas L M, Cruden, David E, Newby
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The dynamic regulation of intravascular thrombus formation is central to our understanding of both acute and chronic atherosclerotic events. The initiation, modification and resolution of thrombus associated with eroded or unstable coronary plaques is critically dependent on the efficacy of endogenous fibrinolysis, a process that is itself reliant upon
Nicholas L M, Cruden, David E, Newby
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D. The kinin system A history and review of the kinin system
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1969Abstract The first two plasma systems, clotting and fibrinolysis, we have so far dealt with in this meeting emerged largely from an analysis of clinically obvious end-results. The kinin system differs in two respects: first, it emerged largely from studies of laboratory artifacts which suggested that a number of pharmacologically ...
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1992
Apparent affinities of kinin agonists and antagonists were determined in terms of pD2 and pA2 respectively, on three isolated smooth muscles: rabbit jugular vein (Rb.J.V.), rabbit aorta (Rb.A.) and guinea pig ileum (G.P.I.). Both kinin agonists and antagonists were evaluated for their ability to induce the release of histamine from rat mastocytes.
D, Regoli +3 more
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Apparent affinities of kinin agonists and antagonists were determined in terms of pD2 and pA2 respectively, on three isolated smooth muscles: rabbit jugular vein (Rb.J.V.), rabbit aorta (Rb.A.) and guinea pig ileum (G.P.I.). Both kinin agonists and antagonists were evaluated for their ability to induce the release of histamine from rat mastocytes.
D, Regoli +3 more
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Kinins and Cardiovascular Diseases
Current Pharmaceutical Design, 2006Kinins are synthesized from their precursors by different enzymes and participate in the regulation of cardiovascular function through bradykinin (BK) B1 and B2 receptors. They modulate blood coagulation by exerting antithrombotic and profibrinolytic actions.
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Kinins, Receptors, Antagonists
1986Kinins are potent myotropic agents acting on a variety of smooth muscle preparations: isolated arteries, veins, intestines, tracheae, urinary bladders, uteri, etc. In these tissues, kinins activate at least two different receptor types, B1 and B2. B1 and B2 receptors for kinins have been identified by measuring the order of potency of agonists and the ...
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