Results 151 to 160 of about 21,873 (185)

Human KIR sequences 2003

Immunogenetics, 2003
We have compiled the nucleotide sequences and their amino acid translations from a total of 89 Killer Immunoglobulin-like Receptor (KIR) alleles, derived from 17 different KIR genes. The alignments use the KIR3DL2*001 allele as a reference sequence. Each of the KIR sequences included in these alignments has been checked and where discrepancies have ...
C A, Garcia, J, Robinson, L A, Guethlein, P, Parham, J A, Madrigal, S G E, Marsh   +5 more
openaire   +2 more sources

KIR genotype distribution among patients with chronic lymphocytic leukemia: Is there a role for KIR 2DS4 and KIR 2DS5 genes?

Gene Reports, 2016
Abstract Introduction The function of natural killer (NK) cells is regulated by different antigen receptors including killer immunoglobulin-like receptors (KIR). In addition to their important role in fighting infection, natural killer cells produce cytotoxicity against some cancer cells. Studies demonstrated that NK cells have a reduced function in
R. Hoteit, A. Bazarbachi, A. Antar, Z. Salem, D. Shammaa, R. Mahfouz   +5 more
openaire   +1 more source

KIR and KIR ligand polymorphism: a new area for clinical applications?

Tissue Antigens, 2013
AbstractKiller immunoglobulin‐like receptors (KIRs) play an essential role in the regulation of natural killer (NK) activity, allowing NK cells to sense and respond to human leukocyte antigen (HLA) class I downregulation, an important hallmark for viral infections and tumor transformation.
FALCO, MICHELA, MORETTA, ALESSANDRO, MORETTA, LORENZO, BOTTINO, CRISTINA   +3 more
openaire   +2 more sources

KIR Genes and Their Role in Spondyloarthropathies

2009
Cellular activity of natural killer cells (NK cells) is defined by the balance between activating and inhibitory signals coming from their receptors. With respect to this response, killer immunoglobulin-like receptors (KIR) are unique because of their diversity and capacity to recognize specific human leukocyte antigen (HLA) class I allotypes.
Roberto, Díaz-Peña, Miguel Angel, Blanco-Gelaz, Carlos, López-Larrea   +2 more
openaire   +2 more sources

KIR Receptors as Key Regulators of NK Cells Activity in Health and Disease

Cells, 2021
Maciej Zielinski, Hanna Zielinska, Anna Dukat-Mazurek   +2 more
exaly  

KIR

1997
A. Neil Barclay, Marion H. Brown, S.K. Alex Law, Andrew J. McKnight, Michael G. Tomlinson, P. Anton van der Merwe   +5 more
openaire   +1 more source

Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes

Immunogenetics, 2002
Markus Uhrberg, Peter Parham, Peter Wernet   +2 more
exaly  

The expanded cattle KIR genes are orthologous to the conserved single-copy KIR3DX1 gene of primates

Immunogenetics, 2007
Lisbeth A Guethlein, Laurent Abi-Rached, John A Hammond   +2 more
exaly  

Short KIR Haplotypes in Pygmy Chimpanzee (Bonobo) Resemble the Conserved Framework of Diverse Human KIR Haplotypes

Journal of Experimental Medicine, 2001
Raja Rajalingam, Erin J Adams, Lisbeth A Guethlein   +2 more
exaly  

KIR

2008
openaire   +1 more source