Results 121 to 130 of about 2,276,672 (229)
CNS Neuroscience &Therapeutics, Volume 31, Issue 11, November 2025.Both pharmacological blockade and genetic knockdown of astrocytic connexin43 channels in the preBötzinger complex induce a high‐frequency breathing pattern, thereby enhancing respiratory motor output. This effect is mediated by astrocytic activation and subsequent ATP release, which activates P2Y1 receptors on somatostatin‐expressing preBötzinger ...
Xue Zhao +11 more
wiley +1 more source
Caractérisation des canaux potassiques du tubule contourné proximal et des propriétés régulatrices des canaux chlorure de la membrane basolatérale des cellules intercalaires du tubule connecteur [PDF]
, 2015 A 10 pS chloride channel at the basolateral side of connecting duct intercalated cells shares properties with the cloned ClC-K2 channel. Patch-clamp experiments show that its activity and the number of active channels increase with (i) membrane ...
Pinelli, Laurent
core +2 more sources
Characterization of Ion Channels Involved in the Proliferative Response of Femoral Artery Smooth Muscle Cells [PDF]
, 2010 31 páginas, 6 figuras, adicionales 6 figuras y 3 tablas.[Objective]: Vascular smooth muscle cells (VSMCs) contribute significantly to occlusive vascular diseases by virtue of their ability to switch to a noncontractile, migratory, and proliferating ...
Barquín, Leire +7 more
core +1 more source
Kaohsiung Journal of Medical Sciences, 2015 The inwardly rectifying K+ current [IK(IR)] allows large inward K+ currents at potentials negative to K+ equilibrium potential (EK) and it becomes small outward K+ currents at those positive to EK. How changes of such currents enriched in glial cells can
Sheng-Nan Wu +4 more
doaj +1 more source
Control of Glutamate Transport by Extracellular Potassium: Basis for a Negative Feedback on Synaptic Transmission. [PDF]
, 2017 Glutamate and K+, both released during neuronal firing, need to be tightly regulated to ensure accurate synaptic transmission. Extracellular glutamate and K+ ([K+]o) are rapidly taken up by glutamate transporters and K+-transporters or channels ...
Chatton, J.Y. +3 more
core +1 more source
Aloin Inhibits Müller Cells Swelling in a Rat Model of Thioacetamide-Induced Hepatic Retinopathy
Molecules, 2018 Swelling of retinal Müller cells is implicated in retinal edema and neuronal degeneration. Müller cell swelling is observed in patients with liver failure and is referred to as hepatic retinopathy. In the present study, we evaluated the effects
Eunsoo Jung, Junghyun Kim
doaj +1 more source
Connexins and gap junctions in the inner ear - it's not just about K(+) recycling [PDF]
, 2014 Normal development, function and repair of the sensory epithelia in the inner ear are all dependent on gap junctional intercellular communication.
Forge, A, Jagger, DJ
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Frontiers in Bioscience-LandmarkBackground: Hypokalemia induces abnormal spontaneous pacemaker activities of cardiomyocytes, which is strongly associated with fatal cardiac arrhythmias caused by hypokalemia. However, the mechanism remains unclear.
Jinhua Lv +3 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2018 Inwardly rectifying potassium channels (Kir) have been historically associated to several cardiovascular disorders. In particular, loss-of-function mutations in the Kir2.1 channel have been reported in cases affected by Andersen-Tawil syndrome while gain-
Anna Binda +7 more
doaj +1 more source
Developmental maturation of astrocytes and pathogenesis of neurodevelopmental disorders [PDF]
, 2013 Recent studies have implicated potentially significant roles for astrocytes in the pathogenesis of neurodevelopmental disorders. Astrocytes undergo a dramatic maturation process following early differentiation from which typical morphology and important ...
Haruki Higashimori +2 more
core +1 more source