Results 111 to 120 of about 2,756 (195)

Association of KISS1R gene polymorphism (rs397515615) with idiopathic female infertility in the northern of Iran [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām
Introduction:  Mutations in the KISS1R gene are among the most critical potential causes of infertility. This gene plays a role in the regulation of the hypothalamus-pituitary-gonadal (HPG) axis and is used in the regulation of reproductive cycles and ...
Peghah Yousefkhah, HamidReza Vaziri, Tooba Mirzapour   +2 more
doaj  

Sensitivities of mRNA expression levels of Kiss1 and its receptor, Kiss1r, to nutritional status are changed during the developmental period in female rats

, 2010
Decreased activity of kisspeptin, the product of the hypothalamic Kiss1 gene, is the major cause of the suppression of reproductive function in subnutritional conditions.
Riyo Kinouchi, Shinobu Fujisawa, Toshiyuki Yasui, Takeshi Iwasa, Masahiro Murakami, Minoru Irahara, Toshiya Matsuzaki, Ganbat Gereltsetseg, Akira Kuwahara   +8 more
core   +1 more source

Kisspeptin a potential therapeutic target in treatment of both metabolic and reproductive dysfunction

Journal of Diabetes
Kisspeptins (KPs) are proteins that were first recognized to have antimetastatic action. Later, the critical role of this peptide in the regulation of reproduction was proved.
Joanna Helena Sliwowska, Nicola Elizabeth Woods, Abdullah Rzgallah Alzahrani, Elpiniki Paspali, Rothwelle Joseph Tate, Valerie Anne Ferro   +5 more
doaj   +1 more source

Assessing the effectiveness of preventing placenta-associated complications in patients with burdened obstetric history and circulating antiphospholipid antibodies

Акушерство, гинекология и репродукция
Introduction. The role of antiphospholipid antibody (APA) carriage in the pathogenesis of pregnancy failure is one of the most recently debated issues.
D. R. Eremeeva, M. S. Zainulina
doaj   +1 more source

KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion [PDF]

, 2011
KISS1 and its receptor, KISS1R, have both been found to be expressed in central nervous system, but few data are present in the literature about their distribution in peripheral nervous structures.
Montella, Andrea Costantino Mario, Ruciński, Marcin, Macchi, Veronica, Porzionato, Andrea, De Caro, Raffaele, Fenu, Grazia, Malendowicz, Ludwik K.   +6 more
core  

KISS1R wt Allele [PDF]

, 2020
openaire   +1 more source

Normosmic idiopathic hypogonadotropic hypogonadism due to a novel homozygous nonsense c.C969A (p.Y323X) mutation in the KISS1R gene in three unrelated families

, 2015
PubMedID: 25262569Objective: The spectrum of genetic alterations in cases of hypogonadotropic hypogonadism continue to expand. However, KISS1R mutations remain rare.
Cesur Y., Ozbek M.N., Dogan M., Demirbilek H., Temiz F., Demir K., Kotan L.D.   +6 more
core   +1 more source

Presence of two alternative splice isoforms of the kisspeptin-1 receptor (kiss1r) in a modern teleost, the Senegalese sole (Solea senegalensis)

, 2013
1st World Conference on Kisspeptin Signaling in the Brain, 8-11 October 2008, CórdobaThe KISSPEPTIN-1 receptor (KISS1R) and its ligands (KISSPEPTINS) are implicated in the regulation of the onset of puberty.
Piferrer, Francesc, Viñas, Jordi, Mechaly, Alejandro S.   +2 more
core  

KISS1 and KISS1R expression in primary and metastatic colorectal cancer.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 2019
Kisspeptins are produced by the KISS1 gene and have tumor-suppressing and anti-metastatic properties. Our aim was to study the expression of KISS1 and its receptor, KISS1R, in colorectal cancer.KISS1 and KISS1R expression was detected using immunohistochemistry in malignant tissue samples from 66 patients (34 men, 32 women) with colorectal ...
Spyridon, Matthaiou, Ioannis D, Kostakis, Stylianos, Kykalos, Nikolaos, Machairas, Eleftherios, Spartalis, Evangelia, Ntikoudi, Maria, Lambropoulou, Anastasios, Karayiannakis, Nikolaos, Machairas   +8 more
openaire   +1 more source

Design and Synthesis of Short-length KISS1R Agonists for the Functional Analysis of an Orphan G Protein-coupled Receptor KISS1R

Design and Synthesis of Short-length KISS1R Agonists for the Functional Analysis of an Orphan G Protein-coupled Receptor KISS1R
学位の種別: 論文博士 審査委員会委員 : （主査）東京大学教授 大和田 智彦, 東京大学教授 金井 求, 東京大学教授 浦野 泰照, 東京大学准教授 花岡 健二郎, 東京大学准教授 石川 ...
openaire   +1 more source